Molecular and functional characterization of dextran production in Weissella spp. - Superior dextran producers for cereal applications (WISEDextran)



Funding: Academy of Finland
Collaboration: Dr. Kati Karina, Dr. Riikka Juvonen, VTT, Finland;
Prof. Arun Goyal, Indian Institute of Technology Guwahati (IITG), Guwahati, India
Project description:
The aim of the WISEDextran project is to improve understanding of the key-factors dictating dextran synthesis in the high-dextran producing Weissella strains to enable controlled and enhanced production of dextrans with tailored properties for diverse applications. The production, properties, and use for in vitro dextran synthesis of dexransucrases will be also studied. The project is divided in five workpackages: 1. Selection of high-dextran producing Weissella strains, 2. Molecular biology of dextran production, 3. Purification and characterization of dextransucrases, 4. Modelling of dextransucrase and dextran production, 5. Performance of Weissella spp. and dextransucrases in bran matrix, which will be carried out in a close collaboration between the consortium partners. The results will form the bases for the efficient industrial exploitation of Weissella species in future. The project also elucidates the hitherto unexplored ecological role of dextran synthesis in these bacteria.
Gällande start-/slutdatum01/01/201231/12/2014


  • 416 Livsmedelsvetenskap
  • 116 Kemi
  • 1182 Biokemi, cell- och molekylärbiologi



Rye bran as fermentation matrix boosts in situ dextran production by Weissella confusa compared to wheat bran

Kajala, I., Mäkelä, J., Coda, R., Shukla, S., Shi, Q., Maina, N. H., Juvonen, R., Ekholm, P., Goyal, A., Tenkanen, M. & Katina, K., apr 2016, I : Applied Microbiology and Biotechnology. 100, 8, s. 3499-3510 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Structure modelling and functional analysis of recombinant dextransucrase from Weissella confusa Cab3 expressed in Lactococcus lactis

Shukla, S., Vermaa, A., Kajala, I., Nyyssölä, A., Baruaha, R., Katina, K. K., Juvonen, R., Tenkanen, T. M. & Goyal, A., 2016, I : Preparative Biochemistry and Biotechnology. 46, 8, s. 822-832 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review