Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer

James H. A. Clubb; Tatiana V. Kudling; Camilla Heinioe; Saru Basnet; Santeri Pakola; Victor Cervera Carrascon; Joao Manuel Santos; Dafne C. A. Quixabeira; Riikka Havunen; Suvi Sorsa; Vincent Zheng; Tuula Salo; Leif Bäck; Katri Aro; Sanni Tulokas; Venla Loimu; Akseli Hemminki

doi:10.3389/fimmu.2022.794251

Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer

James H. A. Clubb, Tatiana V. Kudling, Camilla Heinioe, Saru Basnet, Santeri Pakola, Victor Cervera Carrascon, Joao Manuel Santos, Dafne C. A. Quixabeira, Riikka Havunen, Suvi Sorsa, Vincent Zheng, Tuula Salo, Leif Bäck, Katri Aro, Sanni Tulokas, Venla Loimu, Akseli Hemminki

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	794251
Tidskrift	Frontiers in Immunology
Volym	13
Antal sidor	17
ISSN	1664-3224
DOI	https://doi.org/10.3389/fimmu.2022.794251
Status	Publicerad - 7 mars 2022
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper
3122 Cancersjukdomar

Åtkomst av dokument

10.3389/fimmu.2022.794251

fimmu-13-794251Slutlig publicerad version, 11,7 MBLicens: CC BY

Citera det här

Clubb, J. H. A., Kudling, T. V., Heinioe, C., Basnet, S., Pakola, S., Cervera Carrascon, V., Santos, J. M., Quixabeira, D. C. A., Havunen, R., Sorsa, S., Zheng, V., Salo, T., Bäck, L., Aro, K., Tulokas, S., Loimu, V., & Hemminki, A. (2022). Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer. Frontiers in Immunology, 13, [794251]. https://doi.org/10.3389/fimmu.2022.794251

@article{656f446622fe4ab09bc5dae704b6e895,

title = "Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer",

keywords = "adenovirus, immune checkpoint inhibitor, head and neck cancer, immunotherapy, tertiary lymphoid neogenesis, TNFa, IL2, oncolytic virotherapy, SQUAMOUS-CELL CARCINOMA, INTRAEPITHELIAL NEOPLASIA GRADE-2, TNF-ALPHA, THERAPY, RECURRENT, IMMUNOTHERAPY, RESISTANCE, SURVIVAL, RISK, 3111 Biomedicine, 3122 Cancers",

author = "Clubb, {James H. A.} and Kudling, {Tatiana V.} and Camilla Heinioe and Saru Basnet and Santeri Pakola and {Cervera Carrascon}, Victor and Santos, {Joao Manuel} and Quixabeira, {Dafne C. A.} and Riikka Havunen and Suvi Sorsa and Vincent Zheng and Tuula Salo and Leif B{\"a}ck and Katri Aro and Sanni Tulokas and Venla Loimu and Akseli Hemminki",

year = "2022",

month = mar,

day = "7",

doi = "10.3389/fimmu.2022.794251",

language = "English",

volume = "13",

journal = "Frontiers in Immunology",

issn = "1664-3224",

publisher = "Frontiers Media",

}

Clubb, JHA, Kudling, TV, Heinioe, C, Basnet, S , Pakola, S, Cervera Carrascon, V, Santos, JM, Quixabeira, DCA, Havunen, R, Sorsa, S, Zheng, V , Salo, T , Bäck, L , Aro, K , Tulokas, S , Loimu, V & Hemminki, A 2022, 'Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer', Frontiers in Immunology, vol. 13, 794251. https://doi.org/10.3389/fimmu.2022.794251

Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer. / Clubb, James H. A.; Kudling, Tatiana V.; Heinioe, Camilla et al.

I: Frontiers in Immunology, Vol. 13, 794251, 07.03.2022.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Adenovirus Encoding Tumor Necrosis Factor Alpha and Interleukin 2 Induces a Tertiary Lymphoid Structure Signature in Immune Checkpoint Inhibitor Refractory Head and Neck Cancer

AU - Clubb, James H. A.

AU - Kudling, Tatiana V.

AU - Heinioe, Camilla

AU - Basnet, Saru

AU - Pakola, Santeri

AU - Cervera Carrascon, Victor

AU - Santos, Joao Manuel

AU - Quixabeira, Dafne C. A.

AU - Havunen, Riikka

AU - Sorsa, Suvi

AU - Zheng, Vincent

AU - Salo, Tuula

AU - Bäck, Leif

AU - Aro, Katri

AU - Tulokas, Sanni

AU - Loimu, Venla

AU - Hemminki, Akseli

PY - 2022/3/7

Y1 - 2022/3/7

KW - adenovirus

KW - immune checkpoint inhibitor

KW - head and neck cancer

KW - immunotherapy

KW - tertiary lymphoid neogenesis

KW - TNFa

KW - IL2

KW - oncolytic virotherapy

KW - SQUAMOUS-CELL CARCINOMA

KW - INTRAEPITHELIAL NEOPLASIA GRADE-2

KW - TNF-ALPHA

KW - THERAPY

KW - RECURRENT

KW - IMMUNOTHERAPY

KW - RESISTANCE

KW - SURVIVAL

KW - RISK

KW - 3111 Biomedicine

KW - 3122 Cancers

U2 - 10.3389/fimmu.2022.794251

DO - 10.3389/fimmu.2022.794251

M3 - Article

VL - 13

JO - Frontiers in Immunology

JF - Frontiers in Immunology

SN - 1664-3224

M1 - 794251

ER -