ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

Katja Kaipio; Ping Chen; Pia Roering; Kaisa Huhtinen; Piia Mikkonen; Päivi Östling; Laura Lehtinen; Naziha Mansuri; Taina Korpela; Swapnil Potdar; Johanna Hynninen; Annika Auranen; Seija Grénman; Krister Wennerberg; Sampsa Hautaniemi; Olli Carpén

doi:10.1002/path.5356

ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

Katja Kaipio, Ping Chen, Pia Roering, Kaisa Huhtinen, Piia Mikkonen, Päivi Östling, Laura Lehtinen, Naziha Mansuri, Taina Korpela, Swapnil Potdar, Johanna Hynninen, Annika Auranen, Seija Grénman, Krister Wennerberg, Sampsa Hautaniemi, Olli Carpén

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Journal of Pathology
Volym	250
Utgåva	2
Sidor (från-till)	159-169
Antal sidor	11
ISSN	0022-3417
DOI	https://doi.org/10.1002/path.5356
Status	Publicerad - feb 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3122 Cancersjukdomar

Åtkomst av dokument

10.1002/path.5356

Kaipio_et_al-2019-The_Journal_of_PathologyAccepterat manuskript från författare, 2,2 MBLicens: !!Unspecified

Citera det här

Kaipio, K., Chen, P., Roering, P., Huhtinen, K., Mikkonen, P., Östling, P., Lehtinen, L., Mansuri, N., Korpela, T., Potdar, S., Hynninen, J., Auranen, A., Grénman, S., Wennerberg, K., Hautaniemi, S., & Carpén, O. (2020). ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors. Journal of Pathology, 250(2), 159-169. https://doi.org/10.1002/path.5356

Kaipio, Katja ; Chen, Ping ; Roering, Pia ; Huhtinen, Kaisa ; Mikkonen, Piia ; Östling, Päivi ; Lehtinen, Laura ; Mansuri, Naziha ; Korpela, Taina ; Potdar, Swapnil ; Hynninen, Johanna ; Auranen, Annika ; Grénman, Seija ; Wennerberg, Krister ; Hautaniemi, Sampsa ; Carpén, Olli. / ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors. I: Journal of Pathology. 2020 ; Vol. 250, Nr. 2. s. 159-169.

@article{e3fdadb77aa546b28d1dc454a43d337a,

title = "ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors",

keywords = "3122 Cancers, Ovarian cancer, stem-like cell, patient derived cell line, survival, drug sensitivity, CELLS, CONTRIBUTE, BMI-1, ovarian cancer, ALDEHYDE DEHYDROGENASE, MARKER, IDENTIFICATION, patient-derived cell line, MICROENVIRONMENT, EXPRESSION, EPITHELIAL OVARIAN, AURORA",

author = "Katja Kaipio and Ping Chen and Pia Roering and Kaisa Huhtinen and Piia Mikkonen and P{\"a}ivi {\"O}stling and Laura Lehtinen and Naziha Mansuri and Taina Korpela and Swapnil Potdar and Johanna Hynninen and Annika Auranen and Seija Gr{\'e}nman and Krister Wennerberg and Sampsa Hautaniemi and Olli Carp{\'e}n",

year = "2020",

month = feb,

doi = "10.1002/path.5356",

language = "English",

volume = "250",

pages = "159--169",

journal = "Journal of Pathology",

issn = "0022-3417",

publisher = "John Wiley & Sons Ltd. ",

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}

Kaipio, K, Chen, P, Roering, P, Huhtinen, K, Mikkonen, P , Östling, P, Lehtinen, L, Mansuri, N, Korpela, T, Potdar, S, Hynninen, J, Auranen, A, Grénman, S, Wennerberg, K , Hautaniemi, S & Carpén, O 2020, 'ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors', Journal of Pathology, vol. 250, nr. 2, s. 159-169. https://doi.org/10.1002/path.5356

ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors. / Kaipio, Katja; Chen, Ping; Roering, Pia; Huhtinen, Kaisa; Mikkonen, Piia ; Östling, Päivi; Lehtinen, Laura; Mansuri, Naziha; Korpela, Taina; Potdar, Swapnil; Hynninen, Johanna; Auranen, Annika; Grénman, Seija; Wennerberg, Krister ; Hautaniemi, Sampsa ; Carpén, Olli.

I: Journal of Pathology, Vol. 250, Nr. 2, 02.2020, s. 159-169.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

AU - Kaipio, Katja

AU - Chen, Ping

AU - Roering, Pia

AU - Huhtinen, Kaisa

AU - Mikkonen, Piia

AU - Östling, Päivi

AU - Lehtinen, Laura

AU - Mansuri, Naziha

AU - Korpela, Taina

AU - Potdar, Swapnil

AU - Hynninen, Johanna

AU - Auranen, Annika

AU - Grénman, Seija

AU - Wennerberg, Krister

AU - Hautaniemi, Sampsa

AU - Carpén, Olli

PY - 2020/2

Y1 - 2020/2

KW - 3122 Cancers

KW - Ovarian cancer

KW - stem-like cell

KW - patient derived cell line

KW - survival

KW - drug sensitivity

KW - CELLS

KW - CONTRIBUTE

KW - BMI-1

KW - ovarian cancer

KW - ALDEHYDE DEHYDROGENASE

KW - MARKER

KW - IDENTIFICATION

KW - patient-derived cell line

KW - MICROENVIRONMENT

KW - EXPRESSION

KW - EPITHELIAL OVARIAN

KW - AURORA

U2 - 10.1002/path.5356

DO - 10.1002/path.5356

M3 - Article

VL - 250

SP - 159

EP - 169

JO - Journal of Pathology

JF - Journal of Pathology

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IS - 2

ER -