Amphetamine enantiomers inhibit homomeric alpha 7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans

Daniel R. Garton; Sharmaine G. Ross; Rafael Maldonado-Hernandez; Matthias Quick; Jose A. Lasalde-Dominicci; Jose E. Lizardi-Ortiz

doi:10.1016/j.neuropharm.2018.10.032

Amphetamine enantiomers inhibit homomeric alpha 7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans

Daniel R. Garton, Sharmaine G. Ross, Rafael Maldonado-Hernandez, Matthias Quick, Jose A. Lasalde-Dominicci, Jose E. Lizardi-Ortiz

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Neuropharmacology
Volym	144
Sidor (från-till)	172-183
Antal sidor	12
ISSN	0028-3908
DOI	https://doi.org/10.1016/j.neuropharm.2018.10.032
Status	Publicerad - jan. 2019
Externt publicerad	Ja
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3112 Neurovetenskaper
3124 Neurologi och psykiatri
317 Farmaci

Åtkomst av dokument

10.1016/j.neuropharm.2018.10.032

1-s2.0-S0028390818308190-main-1Slutlig publicerad version, 1,13 MB

Citera det här

@article{a07d579f280b4ad9bbf565bea5a27213,

title = "Amphetamine enantiomers inhibit homomeric alpha 7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans",

keywords = "Alpha 7 nicotinic acetylcholine receptor, Amphetamine-type stimulant, Pharmacological characterization, In silico docking analysis, Amphetamine-induced locomotion, Alpha 7 upregulation, ACETYLCHOLINE-RECEPTORS, HIPPOCAMPAL-NEURONS, LOCOMOTOR-ACTIVITY, DOPAMINE RELEASE, BINDING-SITES, METHAMPHETAMINE, CARBAMYLCHOLINE, DISPOSITION, ANTAGONISTS, MODULATION, 3112 Neurosciences, 3124 Neurology and psychiatry, 317 Pharmacy",

author = "Garton, {Daniel R.} and Ross, {Sharmaine G.} and Rafael Maldonado-Hernandez and Matthias Quick and Lasalde-Dominicci, {Jose A.} and Lizardi-Ortiz, {Jose E.}",

year = "2019",

month = jan,

doi = "10.1016/j.neuropharm.2018.10.032",

language = "English",

volume = "144",

pages = "172--183",

journal = "Neuropharmacology",

issn = "0028-3908",

publisher = "Elsevier Scientific Publ. Co",

}

TY - JOUR

T1 - Amphetamine enantiomers inhibit homomeric alpha 7 nicotinic receptor through a competitive mechanism and within the intoxication levels in humans

AU - Garton, Daniel R.

AU - Ross, Sharmaine G.

AU - Maldonado-Hernandez, Rafael

AU - Quick, Matthias

AU - Lasalde-Dominicci, Jose A.

AU - Lizardi-Ortiz, Jose E.

PY - 2019/1

Y1 - 2019/1

KW - Alpha 7 nicotinic acetylcholine receptor

KW - Amphetamine-type stimulant

KW - Pharmacological characterization

KW - In silico docking analysis

KW - Amphetamine-induced locomotion

KW - Alpha 7 upregulation

KW - ACETYLCHOLINE-RECEPTORS

KW - HIPPOCAMPAL-NEURONS

KW - LOCOMOTOR-ACTIVITY

KW - DOPAMINE RELEASE

KW - BINDING-SITES

KW - METHAMPHETAMINE

KW - CARBAMYLCHOLINE

KW - DISPOSITION

KW - ANTAGONISTS

KW - MODULATION

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

KW - 317 Pharmacy

U2 - 10.1016/j.neuropharm.2018.10.032

DO - 10.1016/j.neuropharm.2018.10.032

M3 - Article

SN - 0028-3908

VL - 144

SP - 172

EP - 183

JO - Neuropharmacology

JF - Neuropharmacology

ER -