Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens.

Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Sammanfattning


The antioxidative potential of the 70% methanolic extract of Ichnocarpus frutescens was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH), the hydrogen peroxide, the nitric oxide, the reducing power and the lipid peroxidation inhibition (thiobarbituric acid-reactive substances production) and the RBC membrane stabilization assays. The extract showed significant antioxidant activities in all these assays in a dose depended manner. The extracts exhibited remarkable activities in reactive oxygen species (ROS) scavenging which could be attributed to the high phenolic content of this extract. Moreover, Ichnocarpus frutescens extract showed strong reducing power and a notable capacity to suppress lipid peroxidation. Suppression of lipid peroxidation and nitric oxide scavenging would be the probable mechanism of the stabilization of the RBC membrane. In the DPPH radical scavenging assay the IC50 value of the extract was found to be 23.75 μg/mL. The extract was found to inhibit the nitric oxide radicals generated from sodium nitroprusside and the IC50 value was found to be 69.69 μg/mL, comparable to the IC50 value of 86.83 μg/mL for the positive control ascorbic acid..
Originalspråkengelska
TidskriftJournal of Natural Remedies
Volym8
Utgåva1
ISSN0972-5547
StatusPublicerad - 2008
MoE-publikationstypA1 Tidskriftsartikel-refererad

Vetenskapsgrenar

  • 119 Övrig naturvetenskap

Citera det här

Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker. (2008). Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens. Journal of Natural Remedies, 8(1).
Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker. . / Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens. I: Journal of Natural Remedies. 2008 ; Vol. 8, Nr. 1.
@article{1d49b23744184db7ab0f148c229cc180,
title = "Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens.",
abstract = "The antioxidative potential of the 70{\%} methanolic extract of Ichnocarpus frutescens was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH), the hydrogen peroxide, the nitric oxide, the reducing power and the lipid peroxidation inhibition (thiobarbituric acid-reactive substances production) and the RBC membrane stabilization assays. The extract showed significant antioxidant activities in all these assays in a dose depended manner. The extracts exhibited remarkable activities in reactive oxygen species (ROS) scavenging which could be attributed to the high phenolic content of this extract. Moreover, Ichnocarpus frutescens extract showed strong reducing power and a notable capacity to suppress lipid peroxidation. Suppression of lipid peroxidation and nitric oxide scavenging would be the probable mechanism of the stabilization of the RBC membrane. In the DPPH radical scavenging assay the IC50 value of the extract was found to be 23.75 μg/mL. The extract was found to inhibit the nitric oxide radicals generated from sodium nitroprusside and the IC50 value was found to be 69.69 μg/mL, comparable to the IC50 value of 86.83 μg/mL for the positive control ascorbic acid..",
keywords = "119 Other natural sciences, NATURAL PRODUCTS",
author = "Majumder, {Muntasir Mamun} and {Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker.}",
year = "2008",
language = "English",
volume = "8",
journal = "Journal of Natural Remedies",
issn = "0972-5547",
publisher = "Natural Remedies Private Limited",
number = "1",

}

Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker. 2008, 'Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens.', Journal of Natural Remedies, vol. 8, nr. 1.

Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens. / Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker. .

I: Journal of Natural Remedies, Vol. 8, Nr. 1, 2008.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

TY - JOUR

T1 - Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens.

AU - Majumder, Muntasir Mamun

AU - Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker.

PY - 2008

Y1 - 2008

N2 - The antioxidative potential of the 70% methanolic extract of Ichnocarpus frutescens was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH), the hydrogen peroxide, the nitric oxide, the reducing power and the lipid peroxidation inhibition (thiobarbituric acid-reactive substances production) and the RBC membrane stabilization assays. The extract showed significant antioxidant activities in all these assays in a dose depended manner. The extracts exhibited remarkable activities in reactive oxygen species (ROS) scavenging which could be attributed to the high phenolic content of this extract. Moreover, Ichnocarpus frutescens extract showed strong reducing power and a notable capacity to suppress lipid peroxidation. Suppression of lipid peroxidation and nitric oxide scavenging would be the probable mechanism of the stabilization of the RBC membrane. In the DPPH radical scavenging assay the IC50 value of the extract was found to be 23.75 μg/mL. The extract was found to inhibit the nitric oxide radicals generated from sodium nitroprusside and the IC50 value was found to be 69.69 μg/mL, comparable to the IC50 value of 86.83 μg/mL for the positive control ascorbic acid..

AB - The antioxidative potential of the 70% methanolic extract of Ichnocarpus frutescens was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH), the hydrogen peroxide, the nitric oxide, the reducing power and the lipid peroxidation inhibition (thiobarbituric acid-reactive substances production) and the RBC membrane stabilization assays. The extract showed significant antioxidant activities in all these assays in a dose depended manner. The extracts exhibited remarkable activities in reactive oxygen species (ROS) scavenging which could be attributed to the high phenolic content of this extract. Moreover, Ichnocarpus frutescens extract showed strong reducing power and a notable capacity to suppress lipid peroxidation. Suppression of lipid peroxidation and nitric oxide scavenging would be the probable mechanism of the stabilization of the RBC membrane. In the DPPH radical scavenging assay the IC50 value of the extract was found to be 23.75 μg/mL. The extract was found to inhibit the nitric oxide radicals generated from sodium nitroprusside and the IC50 value was found to be 69.69 μg/mL, comparable to the IC50 value of 86.83 μg/mL for the positive control ascorbic acid..

KW - 119 Other natural sciences

KW - NATURAL PRODUCTS

M3 - Article

VL - 8

JO - Journal of Natural Remedies

JF - Journal of Natural Remedies

SN - 0972-5547

IS - 1

ER -

Muntasir M. Majumder, Ehsanul H. Mazumder, M. Ashraful Alam, Raushanara Akter, Mustafizur Rahman, Satyajit D. Sarker. . Antioxidant and membrane stabilizing properties of Ichnocarpus frutescens. Journal of Natural Remedies. 2008;8(1).