Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

Eva Ramsay; Manuela Ravina; Sanjay Sarkhel; Sarah Hehir; Neil R. Cameron; Tanja Ilmarinen; Heli Skottman; Jrgen Kjems; Arto Urtti; Marika Ruponen; Astrid Subrizi

doi:10.3390/pharmaceutics12070667

Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

Eva Ramsay, Manuela Ravina, Sanjay Sarkhel, Sarah Hehir, Neil R. Cameron, Tanja Ilmarinen, Heli Skottman, Jrgen Kjems, Arto Urtti, Marika Ruponen, Astrid Subrizi

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	667
Tidskrift	Pharmaceutics
Volym	12
Nummer	7
Antal sidor	17
ISSN	1999-4923
DOI	https://doi.org/10.3390/pharmaceutics12070667
Status	Publicerad - juli 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

317 Farmaci

Åtkomst av dokument

10.3390/pharmaceutics12070667

pharmaceutics-12-00667Slutlig publicerad version, 7,15 MBLicens: CC BY

Citera det här

@article{365dea3487fa4bdb9ff354ac2d998c55,

title = "Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models",

keywords = "siRNA delivery, polyplex, lipoplex, lipidoid, retinal pigment epithelium, physiologically relevant RPE cell model, melanin, melanosome, GENE DELIVERY, INTRACELLULAR TRAFFICKING, OXIDATIVE DAMAGE, INTERFERING RNA, IN-VITRO, INFLAMMATION, TRANSFECTION, MELANIN, DIFFERENTIATION, DEGENERATION, 317 Pharmacy",

author = "Eva Ramsay and Manuela Ravina and Sanjay Sarkhel and Sarah Hehir and Cameron, {Neil R.} and Tanja Ilmarinen and Heli Skottman and Jrgen Kjems and Arto Urtti and Marika Ruponen and Astrid Subrizi",

year = "2020",

month = jul,

doi = "10.3390/pharmaceutics12070667",

language = "English",

volume = "12",

journal = "Pharmaceutics",

issn = "1999-4923",

publisher = "MDPI",

number = "7",

}

TY - JOUR

T1 - Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

AU - Ramsay, Eva

AU - Ravina, Manuela

AU - Sarkhel, Sanjay

AU - Hehir, Sarah

AU - Cameron, Neil R.

AU - Ilmarinen, Tanja

AU - Skottman, Heli

AU - Kjems, Jrgen

AU - Urtti, Arto

AU - Ruponen, Marika

AU - Subrizi, Astrid

PY - 2020/7

Y1 - 2020/7

KW - siRNA delivery

KW - polyplex

KW - lipoplex

KW - lipidoid

KW - retinal pigment epithelium

KW - physiologically relevant RPE cell model

KW - melanin

KW - melanosome

KW - GENE DELIVERY

KW - INTRACELLULAR TRAFFICKING

KW - OXIDATIVE DAMAGE

KW - INTERFERING RNA

KW - IN-VITRO

KW - INFLAMMATION

KW - TRANSFECTION

KW - MELANIN

KW - DIFFERENTIATION

KW - DEGENERATION

KW - 317 Pharmacy

U2 - 10.3390/pharmaceutics12070667

DO - 10.3390/pharmaceutics12070667

M3 - Article

VL - 12

JO - Pharmaceutics

JF - Pharmaceutics

SN - 1999-4923

IS - 7

M1 - 667

ER -