Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications (Book chapter)

M Terracciano, L. De Stefano, Helder Almeida Santos, N.M. Martucci, I. Ruggiero, I. Rendina, N. Migliaccio, A. Lamberti, I. Rea

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

Sammanfattning

Diatomite is a natural porous silica material of sedimentary origin, formed by remains of diatom skeletons called “frustules.” The abundance in many areas of the world and the peculiar physico-chemical properties made diatomite an intriguing material for several applications ranging from food production to pharmaceutics. However, diatomite is a material still rarely used in biomedical applications. In this chapter, the properties of diatom frustules reduced to nanoparticles, with an average diameter less than 350 nm, as potential drug vectors are described. Their biocompatibility, cellular uptake, and capability to transport molecules inside cancer cells are discussed. Preliminary studies of in vivo toxicity are also presented.
Originalspråkengelska
Titel på gästpublikationAlgae - Organisms for Imminent Biotechnology
RedaktörerNooruddin Thajuddin, Dharumadurai Dhanasekaran
Antal sidor25
FörlagINTECHopen
Utgivningsdatumjun 2016
Sidor211-235
ISBN (tryckt)978-953-51-2431-3
ISBN (elektroniskt)978-953-51-2432-0
DOI
StatusPublicerad - jun 2016
MoE-publikationstypA3 Del av bok eller annan forskningsbok

Vetenskapsgrenar

  • 221 Nanoteknologi
  • 318 Medicinsk bioteknologi
  • 317 Farmaci

Citera det här

Terracciano, M., De Stefano, L., Almeida Santos, H., Martucci, N. M., Ruggiero, I., Rendina, I., ... Rea, I. (2016). Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications (Book chapter). I N. Thajuddin, & D. Dhanasekaran (Red.), Algae - Organisms for Imminent Biotechnology (s. 211-235). INTECHopen. https://doi.org/10.5772/63191
Terracciano, M ; De Stefano, L. ; Almeida Santos, Helder ; Martucci, N.M. ; Ruggiero, I. ; Rendina, I. ; Migliaccio, N. ; Lamberti, A. ; Rea, I. . / Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications (Book chapter). Algae - Organisms for Imminent Biotechnology. redaktör / Nooruddin Thajuddin ; Dharumadurai Dhanasekaran. INTECHopen, 2016. s. 211-235
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Terracciano, M, De Stefano, L, Almeida Santos, H, Martucci, NM, Ruggiero, I, Rendina, I, Migliaccio, N, Lamberti, A & Rea, I 2016, Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications (Book chapter). i N Thajuddin & D Dhanasekaran (red), Algae - Organisms for Imminent Biotechnology. INTECHopen, s. 211-235. https://doi.org/10.5772/63191

Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications (Book chapter). / Terracciano, M; De Stefano, L. ; Almeida Santos, Helder; Martucci, N.M. ; Ruggiero, I. ; Rendina, I. ; Migliaccio, N. ; Lamberti, A. ; Rea, I. .

Algae - Organisms for Imminent Biotechnology. red. / Nooruddin Thajuddin; Dharumadurai Dhanasekaran. INTECHopen, 2016. s. 211-235.

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

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Terracciano M, De Stefano L, Almeida Santos H, Martucci NM, Ruggiero I, Rendina I et al. Chapter 9: Silica-based Nanovectors: From Mother Nature to Biomedical Applications (Book chapter). I Thajuddin N, Dhanasekaran D, redaktörer, Algae - Organisms for Imminent Biotechnology. INTECHopen. 2016. s. 211-235 https://doi.org/10.5772/63191