Classification of unknown primary tumors with a data-driven method based on a large microarray reference database

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Sammanfattning

We present a new method to analyze cancer of unknown primary origin (CUP) samples. Our method achieves good results with classification accuracy (88% leave-one-out cross validation for primary tumors from 56 categories, 78% for CUP samples), and can also be used to study CUP samples on a gene-by-gene basis. It is not tied to any a priori defined gene set as many previous methods, and is adaptable to emerging new information.
Bidragets titel på inmatningsspråkClassification of unknown primary tumors with a data-driven method based on a large microarray reference database
Originalspråkengelska
TidskriftGenome medicine
Volym3
Utgåva9
Sidor (från-till)63
Antal sidor12
ISSN1756-994X
DOI
StatusPublicerad - 2011
MoE-publikationstypA1 Tidskriftsartikel-refererad

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  • 3111 Biomedicinska vetenskaper

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