Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis

Yanjuan Tang; Camilla Halvarsson; Amanda Nordigarden; Komal Kumar; Josefine A. Ahsberg; Emma Rorby; Wan Man Wong; Jan-Ingvar Jonsson

doi:10.1016/j.exphem.2015.04.007

Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis

Yanjuan Tang, Camilla Halvarsson, Amanda Nordigarden, Komal Kumar, Josefine A. Ahsberg, Emma Rorby, Wan Man Wong, Jan-Ingvar Jonsson

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Experimental Hematology
Volym	43
Utgåva	7
Sidor (från-till)	554-564
Antal sidor	11
ISSN	0301-472X
DOI	https://doi.org/10.1016/j.exphem.2015.04.007
Status	Publicerad - jul 2015
Externt publicerad	Ja
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3121 Inre medicin

Åtkomst av dokument

10.1016/j.exphem.2015.04.007

CoexpressionSlutlig publicerad version, 1,57 MB

Citera det här

@article{697ac43c72e3404291143aa4d4e482e0,

title = "Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis",

keywords = "ACUTE MYELOID-LEUKEMIA, PROTEIN-KINASE-B, PLECKSTRIN HOMOLOGY DOMAIN, PIK3CA GENE, CYTOKINE-DEPENDENCE, FLT3 MUTATIONS, SURVIVAL, PHOSPHORYLATION, STAT5, TRANSFORMATION, 3121 Internal medicine",

author = "Yanjuan Tang and Camilla Halvarsson and Amanda Nordigarden and Komal Kumar and Ahsberg, {Josefine A.} and Emma Rorby and Wong, {Wan Man} and Jan-Ingvar Jonsson",

year = "2015",

month = jul,

doi = "10.1016/j.exphem.2015.04.007",

language = "English",

volume = "43",

pages = "554--564",

journal = "Experimental Hematology",

issn = "0301-472X",

publisher = "EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC",

number = "7",

}

Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis. / Tang, Yanjuan; Halvarsson, Camilla; Nordigarden, Amanda; Kumar, Komal; Ahsberg, Josefine A.; Rorby, Emma; Wong, Wan Man; Jonsson, Jan-Ingvar.

I: Experimental Hematology, Vol. 43, Nr. 7, 07.2015, s. 554-564.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis

AU - Tang, Yanjuan

AU - Halvarsson, Camilla

AU - Nordigarden, Amanda

AU - Kumar, Komal

AU - Ahsberg, Josefine A.

AU - Rorby, Emma

AU - Wong, Wan Man

AU - Jonsson, Jan-Ingvar

PY - 2015/7

Y1 - 2015/7

KW - ACUTE MYELOID-LEUKEMIA

KW - PROTEIN-KINASE-B

KW - PLECKSTRIN HOMOLOGY DOMAIN

KW - PIK3CA GENE

KW - CYTOKINE-DEPENDENCE

KW - FLT3 MUTATIONS

KW - SURVIVAL

KW - PHOSPHORYLATION

KW - STAT5

KW - TRANSFORMATION

KW - 3121 Internal medicine

U2 - 10.1016/j.exphem.2015.04.007

DO - 10.1016/j.exphem.2015.04.007

M3 - Article

VL - 43

SP - 554

EP - 564

JO - Experimental Hematology

JF - Experimental Hematology

SN - 0301-472X

IS - 7

ER -