Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

Morteza Chalabi Hajkarim; Ella Karjalainen; Mikhail Osipovitch; Konstantinos Dimopoulos; Sandra L. Gordon; Francesca Ambri; Kasper Dindler Rasmussen; Kirsten Gronbaek; Kristian Helin; Krister Wennerberg; Kyoung-Jae Won

doi:10.7554/eLife.73760

Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

Morteza Chalabi Hajkarim, Ella Karjalainen, Mikhail Osipovitch, Konstantinos Dimopoulos, Sandra L. Gordon, Francesca Ambri, Kasper Dindler Rasmussen, Kirsten Gronbaek, Kristian Helin, Krister Wennerberg, Kyoung-Jae Won

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	73760
Tidskrift	eLife
Volym	11
Antal sidor	40
ISSN	2050-084X
DOI	https://doi.org/10.7554/eLife.73760
Status	Publicerad - 15 feb. 2022
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper

Åtkomst av dokument

10.7554/eLife.73760

elife-73760-v1Accepterat manuskript från författare, 34,2 MB

Citera det här

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title = "Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models",

keywords = "high-throughput screening, high-content screening, drug dose response analysis, AML, single cell, drug discovery, sample clustering, Human, Mouse, VISUALIZATION, PATHWAYS, 3111 Biomedicine",

author = "Hajkarim, {Morteza Chalabi} and Ella Karjalainen and Mikhail Osipovitch and Konstantinos Dimopoulos and Gordon, {Sandra L.} and Francesca Ambri and Rasmussen, {Kasper Dindler} and Kirsten Gronbaek and Kristian Helin and Krister Wennerberg and Kyoung-Jae Won",

year = "2022",

month = feb,

day = "15",

doi = "10.7554/eLife.73760",

language = "English",

volume = "11",

journal = "eLife",

issn = "2050-084X",

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TY - JOUR

T1 - Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

AU - Hajkarim, Morteza Chalabi

AU - Karjalainen, Ella

AU - Osipovitch, Mikhail

AU - Dimopoulos, Konstantinos

AU - Gordon, Sandra L.

AU - Ambri, Francesca

AU - Rasmussen, Kasper Dindler

AU - Gronbaek, Kirsten

AU - Helin, Kristian

AU - Wennerberg, Krister

AU - Won, Kyoung-Jae

PY - 2022/2/15

Y1 - 2022/2/15

KW - high-throughput screening

KW - high-content screening

KW - drug dose response analysis

KW - AML

KW - single cell

KW - drug discovery

KW - sample clustering

KW - Human

KW - Mouse

KW - VISUALIZATION

KW - PATHWAYS

KW - 3111 Biomedicine

U2 - 10.7554/eLife.73760

DO - 10.7554/eLife.73760

M3 - Article

VL - 11

JO - eLife

JF - eLife

SN - 2050-084X

M1 - 73760

ER -