Concentrations of medetomidine enantiomers and vatinoxan, an α2-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs

Juhana M. Honkavaara; Marja R. Raekallio; Pernilla M. Syrja; Bruno H. Pypendop; Heather K. Knych; Ira J. Kallio-Kujala; Outi M. Vainio

doi:10.1016/j.vaa.2019.07.004

Concentrations of medetomidine enantiomers and vatinoxan, an α₂-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs

Juhana M. Honkavaara, Marja R. Raekallio, Pernilla M. Syrja, Bruno H. Pypendop, Heather K. Knych, Ira J. Kallio-Kujala, Outi M. Vainio

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Veterinary Anaesthesia and Analgesia
Volym	47
Nummer	1
Sidor (från-till)	47-52
Antal sidor	6
ISSN	1467-2987
DOI	https://doi.org/10.1016/j.vaa.2019.07.004 https://doi.org/10.1016/j.vaa.2019.07.004
Status	Publicerad - jan. 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

413 Veterinärvetenskap

Åtkomst av dokument

1-s2.0-S1467298719302004-mainAccepterat manuskript från författare, 435 KBLicens: CC BY-NC-ND

Citera det här

Honkavaara, J. M., Raekallio, M. R., Syrja, P. M., Pypendop, B. H., Knych, H. K., Kallio-Kujala, I. J., & Vainio, O. M. (2020). Concentrations of medetomidine enantiomers and vatinoxan, an α₂-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs. Veterinary Anaesthesia and Analgesia, 47(1), 47-52. https://doi.org/10.1016/j.vaa.2019.07.004, https://doi.org/10.1016/j.vaa.2019.07.004

@article{4942d2b398a64cbbb73456c7f7b3ec33,

title = "Concentrations of medetomidine enantiomers and vatinoxan, an α2-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs",

keywords = "413 Veterinary science, central nervous system, distribution, dog, medetomidine, MK-467, vatinoxan, L-659,066, CARDIOPULMONARY, PERIPHERAL ALPHA-2-ADRENOCEPTOR ANTAGONIST, DEXMEDETOMIDINE-INDUCED SEDATION, BRADYCARDIA, RECEPTOR ANTAGONIST, PHARMACOKINETICS, INFUSIONS",

author = "Honkavaara, {Juhana M.} and Raekallio, {Marja R.} and Syrja, {Pernilla M.} and Pypendop, {Bruno H.} and Knych, {Heather K.} and Kallio-Kujala, {Ira J.} and Vainio, {Outi M.}",

year = "2020",

month = jan,

doi = "10.1016/j.vaa.2019.07.004",

language = "English",

volume = "47",

pages = "47--52",

journal = "Veterinary Anaesthesia and Analgesia",

issn = "1467-2987",

publisher = "Elsevier Scientific Publ. Co",

number = "1",

}

Honkavaara, JM , Raekallio, MR , Syrja, PM, Pypendop, BH, Knych, HK, Kallio-Kujala, IJ & Vainio, OM 2020, 'Concentrations of medetomidine enantiomers and vatinoxan, an α₂-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs', Veterinary Anaesthesia and Analgesia, vol. 47, nr. 1, s. 47-52. https://doi.org/10.1016/j.vaa.2019.07.004, https://doi.org/10.1016/j.vaa.2019.07.004

Concentrations of medetomidine enantiomers and vatinoxan, an α₂-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs. / Honkavaara, Juhana M.; Raekallio, Marja R.; Syrja, Pernilla M. et al.

I: Veterinary Anaesthesia and Analgesia, Vol. 47, Nr. 1, 01.2020, s. 47-52.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Concentrations of medetomidine enantiomers and vatinoxan, an α2-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs

AU - Honkavaara, Juhana M.

AU - Raekallio, Marja R.

AU - Syrja, Pernilla M.

AU - Pypendop, Bruno H.

AU - Knych, Heather K.

AU - Kallio-Kujala, Ira J.

AU - Vainio, Outi M.

PY - 2020/1

Y1 - 2020/1

KW - 413 Veterinary science

KW - central nervous system

KW - distribution

KW - dog

KW - medetomidine

KW - MK-467

KW - vatinoxan

KW - L-659,066

KW - CARDIOPULMONARY

KW - PERIPHERAL ALPHA-2-ADRENOCEPTOR ANTAGONIST

KW - DEXMEDETOMIDINE-INDUCED SEDATION

KW - BRADYCARDIA

KW - RECEPTOR ANTAGONIST

KW - PHARMACOKINETICS

KW - INFUSIONS

U2 - 10.1016/j.vaa.2019.07.004

DO - 10.1016/j.vaa.2019.07.004

M3 - Article

VL - 47

SP - 47

EP - 52

JO - Veterinary Anaesthesia and Analgesia

JF - Veterinary Anaesthesia and Analgesia

SN - 1467-2987

IS - 1

ER -

Honkavaara JM , Raekallio MR , Syrja PM, Pypendop BH, Knych HK, Kallio-Kujala IJ et al. Concentrations of medetomidine enantiomers and vatinoxan, an α₂-adrenoceptor antagonist, in plasma and central nervous tissue after intravenous coadministration in dogs. Veterinary Anaesthesia and Analgesia. 2020 jan.;47(1):47-52. Epub 2019 aug. 29. doi: 10.1016/j.vaa.2019.07.004, 10.1016/j.vaa.2019.07.004