Copolymers: Drug Delivery (Book Chapter)

Kobra Rostamizadeh, Mohammad-Ali Shahbazi, Mehrdad Hamidi, Hélder A. Santos

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

Sammanfattning

Advances in the pharmaceutical field to develop novel drug delivery systems are increasing rapidly and contributing to improved drug safety and efficacy via modifications in the physicochemical properties of the drug of interest, which eventually leads to improved pharmacokinetic profiles. One important class of materials that has opened new avenues to overcome some of the limitations of the conventional drug dosage forms are copolymers. Copolymer materials comprise at least two structurally different monomers linked together in different arrangements via covalent bonds. As a consequence of the inherent variations in hydrophilicity, solubility, and other physicochemical properties of different polymeric blocks, copolymers are able to form several types of structures, mainly including micelles, polymersomes, and hydrogels. In this entry, we highlight some of the basic principles and developments of copolymers applications as therapeutic delivery systems, particularly the most common methods of synthesis of copolymers, the micellar-shaped copolymers, polymersomes, and hydrogels, while pointing out the most relevant references in the field. Finally, we will conclude with an overview of the potential of copolymers in the future of drug delivery.
Originalspråkengelska
Titel på gästpublikationEncyclopedia of Biomedical Polymers and Polymeric Biomaterials
RedaktörerM. Mishra
Antal sidor11
FörlagCRC Press, Taylor & Francis Group
Utgivningsdatum4 dec 2015
Utgåva1st
Sidor2192-2202
ISBN (elektroniskt)1-4398-9879-0
StatusPublicerad - 4 dec 2015
MoE-publikationstypA3 Del av bok eller annan forskningsbok

Vetenskapsgrenar

  • 317 Farmaci

Citera det här

Rostamizadeh, K., Shahbazi, M-A., Hamidi, M., & Santos, H. A. (2015). Copolymers: Drug Delivery (Book Chapter). I M. Mishra (Red.), Encyclopedia of Biomedical Polymers and Polymeric Biomaterials (1st red., s. 2192-2202). CRC Press, Taylor & Francis Group.
Rostamizadeh, Kobra ; Shahbazi, Mohammad-Ali ; Hamidi, Mehrdad ; Santos, Hélder A. / Copolymers: Drug Delivery (Book Chapter). Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. redaktör / M. Mishra. 1st. red. CRC Press, Taylor & Francis Group, 2015. s. 2192-2202
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Rostamizadeh, K, Shahbazi, M-A, Hamidi, M & Santos, HA 2015, Copolymers: Drug Delivery (Book Chapter). i M Mishra (red.), Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. 1st uppl, CRC Press, Taylor & Francis Group, s. 2192-2202.

Copolymers: Drug Delivery (Book Chapter). / Rostamizadeh, Kobra ; Shahbazi, Mohammad-Ali; Hamidi, Mehrdad ; Santos, Hélder A.

Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. red. / M. Mishra. 1st. red. CRC Press, Taylor & Francis Group, 2015. s. 2192-2202.

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

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Rostamizadeh K, Shahbazi M-A, Hamidi M, Santos HA. Copolymers: Drug Delivery (Book Chapter). I Mishra M, redaktör, Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. 1st red. CRC Press, Taylor & Francis Group. 2015. s. 2192-2202