Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants

Cristina N. Alexandru-Crivac; Christian Umeobika; Niina Leikoski; Jouni Jokela; Kirstie A. Rickaby; Andre M. Grilo; Peter Sjö; Alleyn T. Plowright; Mohannad Idress; Eike Siebs; Ada Nneoyi-Egbe; Matti Wahlsten; Kaarina Sivonen; Marcel Jaspars; Laurent Trembleau; David P. Fewer; Wael E. Houssen

doi:10.1039/c7cc05913b

Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants

Cristina N. Alexandru-Crivac, Christian Umeobika, Niina Leikoski, Jouni Jokela, Kirstie A. Rickaby, Andre M. Grilo, Peter Sjö, Alleyn T. Plowright, Mohannad Idress, Eike Siebs, Ada Nneoyi-Egbe, Matti Wahlsten, Kaarina Sivonen, Marcel Jaspars, Laurent Trembleau, David P. Fewer, Wael E. Houssen

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Chemical Communications
Volym	53
Utgåva	77
Sidor (från-till)	10656-10659
Antal sidor	4
ISSN	1359-7345
DOI	https://doi.org/10.1039/c7cc05913b
Status	Publicerad - 4 okt 2017
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

116 Kemi
1183 Växtbiologi, mikrobiologi, virologi

Åtkomst av dokument

10.1039/c7cc05913b

Citera det här

Alexandru-Crivac, C. N., Umeobika, C., Leikoski, N., Jokela, J., Rickaby, K. A., Grilo, A. M., Sjö, P., Plowright, A. T., Idress, M., Siebs, E., Nneoyi-Egbe, A., Wahlsten, M., Sivonen, K., Jaspars, M., Trembleau, L., Fewer, D. P., & Houssen, W. E. (2017). Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants. Chemical Communications, 53(77), 10656-10659. https://doi.org/10.1039/c7cc05913b

Alexandru-Crivac, Cristina N. ; Umeobika, Christian ; Leikoski, Niina ; Jokela, Jouni ; Rickaby, Kirstie A. ; Grilo, Andre M. ; Sjö, Peter ; Plowright, Alleyn T. ; Idress, Mohannad ; Siebs, Eike ; Nneoyi-Egbe, Ada ; Wahlsten, Matti ; Sivonen, Kaarina ; Jaspars, Marcel ; Trembleau, Laurent ; Fewer, David P. ; Houssen, Wael E. / Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants. I: Chemical Communications. 2017 ; Vol. 53, Nr. 77. s. 10656-10659.

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title = "Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants",

keywords = "DRUG DISCOVERY, MACROCYCLIZATION, LIBRARIES, FAMILY, BIOSYNTHESIS, MECHANISM, SERINE, TOOLS, COLI, 116 Chemical sciences, 1183 Plant biology, microbiology, virology",

author = "Alexandru-Crivac, {Cristina N.} and Christian Umeobika and Niina Leikoski and Jouni Jokela and Rickaby, {Kirstie A.} and Grilo, {Andre M.} and Peter Sj{\"o} and Plowright, {Alleyn T.} and Mohannad Idress and Eike Siebs and Ada Nneoyi-Egbe and Matti Wahlsten and Kaarina Sivonen and Marcel Jaspars and Laurent Trembleau and Fewer, {David P.} and Houssen, {Wael E.}",

year = "2017",

month = oct,

day = "4",

doi = "10.1039/c7cc05913b",

language = "English",

volume = "53",

pages = "10656--10659",

journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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Alexandru-Crivac, CN, Umeobika, C, Leikoski, N, Jokela, J, Rickaby, KA, Grilo, AM, Sjö, P, Plowright, AT, Idress, M, Siebs, E, Nneoyi-Egbe, A, Wahlsten, M , Sivonen, K, Jaspars, M, Trembleau, L, Fewer, DP & Houssen, WE 2017, 'Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants', Chemical Communications, vol. 53, nr. 77, s. 10656-10659. https://doi.org/10.1039/c7cc05913b

Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants. / Alexandru-Crivac, Cristina N.; Umeobika, Christian; Leikoski, Niina; Jokela, Jouni; Rickaby, Kirstie A.; Grilo, Andre M.; Sjö, Peter; Plowright, Alleyn T.; Idress, Mohannad; Siebs, Eike; Nneoyi-Egbe, Ada; Wahlsten, Matti ; Sivonen, Kaarina; Jaspars, Marcel; Trembleau, Laurent; Fewer, David P.; Houssen, Wael E.

I: Chemical Communications, Vol. 53, Nr. 77, 04.10.2017, s. 10656-10659.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants

AU - Alexandru-Crivac, Cristina N.

AU - Umeobika, Christian

AU - Leikoski, Niina

AU - Jokela, Jouni

AU - Rickaby, Kirstie A.

AU - Grilo, Andre M.

AU - Sjö, Peter

AU - Plowright, Alleyn T.

AU - Idress, Mohannad

AU - Siebs, Eike

AU - Nneoyi-Egbe, Ada

AU - Wahlsten, Matti

AU - Sivonen, Kaarina

AU - Jaspars, Marcel

AU - Trembleau, Laurent

AU - Fewer, David P.

AU - Houssen, Wael E.

PY - 2017/10/4

Y1 - 2017/10/4

KW - DRUG DISCOVERY

KW - MACROCYCLIZATION

KW - LIBRARIES

KW - FAMILY

KW - BIOSYNTHESIS

KW - MECHANISM

KW - SERINE

KW - TOOLS

KW - COLI

KW - 116 Chemical sciences

KW - 1183 Plant biology, microbiology, virology

U2 - 10.1039/c7cc05913b

DO - 10.1039/c7cc05913b

M3 - Article

VL - 53

SP - 10656

EP - 10659

JO - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 77

ER -