Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs

Jing Chen; Jonas Bacelis; Pol Sole-Navais; Amit Srivastava; Julius Juodakis; Amy Rouse; Mikko Hallman; Kari Teramo; Mads Melbye; Bjarke Feenstra; Rachel M. Freathy; George Davey Smith; Deborah A. Lawlor; Jeffrey C. Murray; Scott M. Williams; Bo Jacobsson; Louis J. Muglia; Ge Zhang

doi:10.1371/journal.pmed.1003305

Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs

Jing Chen, Jonas Bacelis, Pol Sole-Navais, Amit Srivastava, Julius Juodakis, Amy Rouse, Mikko Hallman, Kari Teramo, Mads Melbye, Bjarke Feenstra, Rachel M. Freathy, George Davey Smith, Deborah A. Lawlor, Jeffrey C. Murray, Scott M. Williams, Bo Jacobsson, Louis J. Muglia, Ge Zhang

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	1003305
Tidskrift	PLoS Medicine
Volym	17
Nummer	8
Antal sidor	28
ISSN	1549-1277
DOI	https://doi.org/10.1371/journal.pmed.1003305
Status	Publicerad - 25 aug. 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

1184 Genetik, utvecklingsbiologi, fysiologi
3123 Kvinno- och barnsjukdomar

Åtkomst av dokument

10.1371/journal.pmed.1003305

journal.pmed.1003305Slutlig publicerad version, 2,44 MBLicens: CC BY

Citera det här

Chen, J., Bacelis, J., Sole-Navais, P., Srivastava, A., Juodakis, J., Rouse, A., Hallman, M., Teramo, K., Melbye, M., Feenstra, B., Freathy, R. M., Smith, G. D., Lawlor, D. A., Murray, J. C., Williams, S. M., Jacobsson, B., Muglia, L. J., & Zhang, G. (2020). Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs. PLoS Medicine, 17(8), [1003305]. https://doi.org/10.1371/journal.pmed.1003305

@article{74dad2f2824b41d8a98c939d8d4afcaf,

title = "Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs",

keywords = "1184 Genetics, developmental biology, physiology, 3123 Gynaecology and paediatrics, DEVELOPMENTAL ORIGINS, BLOOD-PRESSURE, RISK-FACTORS, WEIGHT, PREGNANCY, DISEASE, TRAITS, DETERMINANTS, HYPOTHESIS, OBESITY",

author = "Jing Chen and Jonas Bacelis and Pol Sole-Navais and Amit Srivastava and Julius Juodakis and Amy Rouse and Mikko Hallman and Kari Teramo and Mads Melbye and Bjarke Feenstra and Freathy, {Rachel M.} and Smith, {George Davey} and Lawlor, {Deborah A.} and Murray, {Jeffrey C.} and Williams, {Scott M.} and Bo Jacobsson and Muglia, {Louis J.} and Ge Zhang",

year = "2020",

month = aug,

day = "25",

doi = "10.1371/journal.pmed.1003305",

language = "English",

volume = "17",

journal = "PLoS Medicine",

issn = "1549-1277",

publisher = "PUBLIC LIBRARY OF SCIENCE",

number = "8",

}

Chen, J, Bacelis, J, Sole-Navais, P, Srivastava, A, Juodakis, J, Rouse, A, Hallman, M, Teramo, K, Melbye, M, Feenstra, B, Freathy, RM, Smith, GD, Lawlor, DA, Murray, JC, Williams, SM, Jacobsson, B, Muglia, LJ & Zhang, G 2020, 'Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs', PLoS Medicine, vol. 17, nr. 8, 1003305. https://doi.org/10.1371/journal.pmed.1003305

Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs. / Chen, Jing; Bacelis, Jonas; Sole-Navais, Pol et al.

I: PLoS Medicine, Vol. 17, Nr. 8, 1003305, 25.08.2020.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs

AU - Chen, Jing

AU - Bacelis, Jonas

AU - Sole-Navais, Pol

AU - Srivastava, Amit

AU - Juodakis, Julius

AU - Rouse, Amy

AU - Hallman, Mikko

AU - Teramo, Kari

AU - Melbye, Mads

AU - Feenstra, Bjarke

AU - Freathy, Rachel M.

AU - Smith, George Davey

AU - Lawlor, Deborah A.

AU - Murray, Jeffrey C.

AU - Williams, Scott M.

AU - Jacobsson, Bo

AU - Muglia, Louis J.

AU - Zhang, Ge

PY - 2020/8/25

Y1 - 2020/8/25

KW - 1184 Genetics, developmental biology, physiology

KW - 3123 Gynaecology and paediatrics

KW - DEVELOPMENTAL ORIGINS

KW - BLOOD-PRESSURE

KW - RISK-FACTORS

KW - WEIGHT

KW - PREGNANCY

KW - DISEASE

KW - TRAITS

KW - DETERMINANTS

KW - HYPOTHESIS

KW - OBESITY

U2 - 10.1371/journal.pmed.1003305

DO - 10.1371/journal.pmed.1003305

M3 - Article

VL - 17

JO - PLoS Medicine

JF - PLoS Medicine

SN - 1549-1277

IS - 8

M1 - 1003305

ER -

Chen J, Bacelis J, Sole-Navais P, Srivastava A, Juodakis J, Rouse A et al. Dissecting maternal and fetal genetic effects underlying the associations between maternal phenotypes, birth outcomes, and adult phenotypes: A mendelian-randomization and haplotype-based genetic score analysis in 10,734 mother–infant pairs. PLoS Medicine. 2020 aug. 25;17(8):1003305. doi: 10.1371/journal.pmed.1003305