DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression

Satu Mäki-Nevala, Satu Valo, Ari Ristimaki, Virinder Sarhadi, Sakari Knuutila, Minna Nyström, Laura Renkonen-Sinisalo, Anna Lepistö, Jukka-Pekka Mecklin, Päivi Peltomäki

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Originalspråkengelska
TidskriftEBioMedicine
Volym39
Sidor (från-till)280-291
Antal sidor12
ISSN2352-3964
DOI
StatusPublicerad - jan 2019
MoE-publikationstypA1 Tidskriftsartikel-refererad

Vetenskapsgrenar

  • 3111 Biomedicinska vetenskaper
  • 3121 Inre medicin

Citera det här

@article{2979e9b47a4841c0a49bd8cd204a7fd9,
title = "DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression",
keywords = "Lynch syndrome, Colorectal adenoma, DNA methylation, DNA mismatch repair, UNE-1 methylation, Mutation, Tumotigenesis, Tumor suppressor, MICROSATELLITE INSTABILITY, COLORECTAL ADENOMAS, BRAF MUTATION, COPY NUMBER, CANCER, GENE, DEFICIENCY, PHENOTYPE, TUMORS, HYPOMETHYLATION, 3111 Biomedicine, 3121 Internal medicine",
author = "Satu M{\"a}ki-Nevala and Satu Valo and Ari Ristimaki and Virinder Sarhadi and Sakari Knuutila and Minna Nystr{\"o}m and Laura Renkonen-Sinisalo and Anna Lepist{\"o} and Jukka-Pekka Mecklin and P{\"a}ivi Peltom{\"a}ki",
year = "2019",
month = "1",
doi = "10.1016/j.ebiom.2018.12.018",
language = "English",
volume = "39",
pages = "280--291",
journal = "EBioMedicine",
issn = "2352-3964",
publisher = "Elsevier Scientific Publ. Co",

}

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression. / Mäki-Nevala, Satu; Valo, Satu; Ristimaki, Ari; Sarhadi, Virinder; Knuutila, Sakari; Nyström, Minna; Renkonen-Sinisalo, Laura; Lepistö, Anna; Mecklin, Jukka-Pekka; Peltomäki, Päivi.

I: EBioMedicine, Vol. 39, 01.2019, s. 280-291.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

TY - JOUR

T1 - DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression

AU - Mäki-Nevala, Satu

AU - Valo, Satu

AU - Ristimaki, Ari

AU - Sarhadi, Virinder

AU - Knuutila, Sakari

AU - Nyström, Minna

AU - Renkonen-Sinisalo, Laura

AU - Lepistö, Anna

AU - Mecklin, Jukka-Pekka

AU - Peltomäki, Päivi

PY - 2019/1

Y1 - 2019/1

KW - Lynch syndrome

KW - Colorectal adenoma

KW - DNA methylation

KW - DNA mismatch repair

KW - UNE-1 methylation

KW - Mutation

KW - Tumotigenesis

KW - Tumor suppressor

KW - MICROSATELLITE INSTABILITY

KW - COLORECTAL ADENOMAS

KW - BRAF MUTATION

KW - COPY NUMBER

KW - CANCER

KW - GENE

KW - DEFICIENCY

KW - PHENOTYPE

KW - TUMORS

KW - HYPOMETHYLATION

KW - 3111 Biomedicine

KW - 3121 Internal medicine

U2 - 10.1016/j.ebiom.2018.12.018

DO - 10.1016/j.ebiom.2018.12.018

M3 - Article

VL - 39

SP - 280

EP - 291

JO - EBioMedicine

JF - EBioMedicine

SN - 2352-3964

ER -