Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood-Retinal Barrier Model for Use in Early Drug Discovery

Laura Hellinen; Heidi Hongisto; Eva Ramsay; Kai Kaarniranta; Kati-Sisko Vellonen; Heli Skottman; Marika Ruponen

doi:10.3390/pharmaceutics12020176

Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood-Retinal Barrier Model for Use in Early Drug Discovery

Laura Hellinen, Heidi Hongisto, Eva Ramsay, Kai Kaarniranta, Kati-Sisko Vellonen, Heli Skottman, Marika Ruponen

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	176
Tidskrift	Pharmaceutics
Volym	12
Nummer	2
Antal sidor	13
ISSN	1999-4923
DOI	https://doi.org/10.3390/pharmaceutics12020176
Status	Publicerad - feb. 2020
MoE-publikationstyp	Ej behörig

Bibliografisk information

Retraction published on 9 March 2022, see Pharmaceutics 2022, 14(3), 595.

Vetenskapsgrenar

317 Farmaci

Åtkomst av dokument

10.3390/pharmaceutics12020176Licens: CC BY

pharmaceutics-12-00176-v2Slutlig publicerad version, 653 KBLicens: CC BY

Citera det här

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title = "Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood-Retinal Barrier Model for Use in Early Drug Discovery",

keywords = "retinal pigment epithelium, outer blood-retinal barrier, cell models, drug permeation, differentiation, tight junctions, ocular drug delivery, PIGMENT EPITHELIUM, PLASMA-MEMBRANES, MELANIN BINDING, ARPE-19 CELLS, EXPRESSION, PERMEABILITY, PREDICTION, TISSUE, 317 Pharmacy",

author = "Laura Hellinen and Heidi Hongisto and Eva Ramsay and Kai Kaarniranta and Kati-Sisko Vellonen and Heli Skottman and Marika Ruponen",

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AU - Hongisto, Heidi

AU - Ramsay, Eva

AU - Kaarniranta, Kai

AU - Vellonen, Kati-Sisko

AU - Skottman, Heli

AU - Ruponen, Marika

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KW - differentiation

KW - tight junctions

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KW - PIGMENT EPITHELIUM

KW - PLASMA-MEMBRANES

KW - MELANIN BINDING

KW - ARPE-19 CELLS

KW - EXPRESSION

KW - PERMEABILITY

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KW - TISSUE

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