Evaluation of cobas® Liat® Cdiff, STANDARD™ M10 C. difficile and Xpert® C. difficile BT assays for rapid detection of toxigenic Clostridioides difficile

Juulia Suominen, Suvi Korhonen, Heini Kutvonen, Hanna Jarva, Anu Pätäri-Sampo, Raisa Loginov

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Sammanfattning

We evaluated the analytical performance of three commercial molecular assays for rapid detection of Clostridioides difficile toxin B in stool samples. The results were compared with results from the BD MAX™ Cdiff assay. We analyzed forty negative and thirty-two positive stool samples with three rapid assays: Roche cobas® Liat® Cdiff, SD Biosensor STANDARD™ M10 C. difficile and Cepheid Xpert® C. difficile BT. The assays demonstrated a sensitivity of 96.9 %, 96.9 % and 100.0 % and a specificity of 100 %, 97.5 % and 97.5 %, respectively. There is limited data available on the analytical performance of the newly introduced STANDARD™ M10 C. difficile assay. In this study, all three rapid assays demonstrated similarly high analytical performance and can be used for detection of toxigenic C. difficile.

Originalspråkengelska
Artikelnummer107043
TidskriftJournal of Microbiological Methods
Volym226
Antal sidor4
ISSN0167-7012
DOI
StatusPublicerad - nov. 2024
MoE-publikationstypA1 Tidskriftsartikel-refererad

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  • 11832 Mikrobiologi och virologi

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