Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease

Oveis Jamialahmadi; Rosellina Margherita Mancina; Ester Ciociola; Federica Tavaglione; Panu K. Luukkonen; Guido Baselli; Francesco Malvestiti; Dorothee Thuillier; Violeta Raverdy; Ville Mannisto; Rosaria Maria Pipitone; Grazia Pennisi; Daniele Prati; Rocco Spagnuolo; Salvatore Petta; Jussi Pihlajamaki; Francois Pattou; Hannele Yki-Järvinen; Luca Valenti; Stefano Romeo

doi:10.1053/j.gastro.2020.12.023

Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease

Oveis Jamialahmadi
, Rosellina Margherita Mancina
, Ester Ciociola
, Federica Tavaglione
, Panu K. Luukkonen
, Guido Baselli
, Francesco Malvestiti
, Dorothee Thuillier
, Violeta Raverdy
, Ville Mannisto
, Rosaria Maria Pipitone
, Grazia Pennisi
, Daniele Prati
, Rocco Spagnuolo
, Salvatore Petta
, Jussi Pihlajamaki
, Francois Pattou
, Hannele Yki-Järvinen
, Luca Valenti
, Stefano Romeo

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Gastroenterology
Volym	160
Nummer	5
Sidor (från-till)	1634-+
Antal sidor	20
ISSN	0016-5085
DOI	https://doi.org/10.1053/j.gastro.2020.12.023
Status	Publicerad - mars 2021
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3121 Allmänmedicin, inre medicin och annan klinisk medicin

Åtkomst av dokument

10.1053/j.gastro.2020.12.023

PIIS0016508520355621Slutlig publicerad version, 3 MBLicens: CC BY

Citera det här

Jamialahmadi, O., Mancina, R. M., Ciociola, E., Tavaglione, F., Luukkonen, P. K., Baselli, G., Malvestiti, F., Thuillier, D., Raverdy, V., Mannisto, V., Pipitone, R. M., Pennisi, G., Prati, D., Spagnuolo, R., Petta, S., Pihlajamaki, J., Pattou, F., Yki-Järvinen, H., Valenti, L., & Romeo, S. (2021). Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease. Gastroenterology, 160(5), 1634-+. https://doi.org/10.1053/j.gastro.2020.12.023

@article{bc3da21d731f44d8928b3b7185907ee6,

title = "Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease",

keywords = "Nonalcoholic Fatty Liver Disease, NAFLD, Transaminase, Metabolic Associated Fatty Liver Disease, MAFLD, RNA-SEQ DATA, ENRICHMENT ANALYSIS, CONFERS SUSCEPTIBILITY, INSULIN-RESISTANCE, HEPATIC STEATOSIS, X-RECEPTOR, GENE, GENOME, PATHOGENICITY, MUTATIONS, 3121 General medicine, internal medicine and other clinical medicine",

author = "Oveis Jamialahmadi and Mancina, \{Rosellina Margherita\} and Ester Ciociola and Federica Tavaglione and Luukkonen, \{Panu K.\} and Guido Baselli and Francesco Malvestiti and Dorothee Thuillier and Violeta Raverdy and Ville Mannisto and Pipitone, \{Rosaria Maria\} and Grazia Pennisi and Daniele Prati and Rocco Spagnuolo and Salvatore Petta and Jussi Pihlajamaki and Francois Pattou and Hannele Yki-J{\"a}rvinen and Luca Valenti and Stefano Romeo",

year = "2021",

month = mar,

doi = "10.1053/j.gastro.2020.12.023",

language = "English",

volume = "160",

pages = "1634--+",

journal = "Gastroenterology",

issn = "0016-5085",

publisher = "W.B. Saunders",

number = "5",

}

Jamialahmadi, O, Mancina, RM, Ciociola, E, Tavaglione, F, Luukkonen, PK, Baselli, G, Malvestiti, F, Thuillier, D, Raverdy, V, Mannisto, V, Pipitone, RM, Pennisi, G, Prati, D, Spagnuolo, R, Petta, S, Pihlajamaki, J, Pattou, F, Yki-Järvinen, H, Valenti, L & Romeo, S 2021, 'Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease', Gastroenterology, vol. 160, nr. 5, s. 1634-+. https://doi.org/10.1053/j.gastro.2020.12.023

TY - JOUR

T1 - Exome-Wide Association Study on Alanine Aminotransferase Identifies Sequence Variants in the GPAM and APOE Associated With Fatty Liver Disease

AU - Jamialahmadi, Oveis

AU - Mancina, Rosellina Margherita

AU - Ciociola, Ester

AU - Tavaglione, Federica

AU - Luukkonen, Panu K.

AU - Baselli, Guido

AU - Malvestiti, Francesco

AU - Thuillier, Dorothee

AU - Raverdy, Violeta

AU - Mannisto, Ville

AU - Pipitone, Rosaria Maria

AU - Pennisi, Grazia

AU - Prati, Daniele

AU - Spagnuolo, Rocco

AU - Petta, Salvatore

AU - Pihlajamaki, Jussi

AU - Pattou, Francois

AU - Yki-Järvinen, Hannele

AU - Valenti, Luca

AU - Romeo, Stefano

PY - 2021/3

Y1 - 2021/3

KW - Nonalcoholic Fatty Liver Disease

KW - NAFLD

KW - Transaminase

KW - Metabolic Associated Fatty Liver Disease

KW - MAFLD

KW - RNA-SEQ DATA

KW - ENRICHMENT ANALYSIS

KW - CONFERS SUSCEPTIBILITY

KW - INSULIN-RESISTANCE

KW - HEPATIC STEATOSIS

KW - X-RECEPTOR

KW - GENE

KW - GENOME

KW - PATHOGENICITY

KW - MUTATIONS

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1053/j.gastro.2020.12.023

DO - 10.1053/j.gastro.2020.12.023

M3 - Article

SN - 0016-5085

VL - 160

SP - 1634-+

JO - Gastroenterology

JF - Gastroenterology

IS - 5

ER -