Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Žiga Skok; Michaela Barančoková; Ondřej Benek; Cristina Durante Cruz; Päivi Tammela; Tihomir Tomašič; Nace Zidar; Lucija Peterlin Mašič; Anamarija Zega; Clare E. M. Stevenson; Julia E. A. Mundy; David M. Lawson; Anthony Maxwell; Danijel Kikelj; Janez Ilaš

doi:10.1021/acsmedchemlett.0c00416

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Žiga Skok, Michaela Barančoková, Ondřej Benek, Cristina Durante Cruz, Päivi Tammela, Tihomir Tomašič, Nace Zidar, Lucija Peterlin Mašič, Anamarija Zega, Clare E. M. Stevenson, Julia E. A. Mundy, David M. Lawson, Anthony Maxwell, Danijel Kikelj, Janez Ilaš

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	ACS Medicinal Chemistry Letters
Volym	11
Nummer	12
Sidor (från-till)	2433-2440
Antal sidor	8
ISSN	1948-5875
DOI	https://doi.org/10.1021/acsmedchemlett.0c00416
Status	Publicerad - 10 dec. 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

317 Farmaci

Åtkomst av dokument

10.1021/acsmedchemlett.0c00416

Skok et al 2020 AcceptedAccepterat manuskript från författare, 500 KB

EC-FP7-KBBE-2009-3-2-01-245137: Exploring Marine Resources for Bioactive Compounds: From Discovery to Sustainable Production and Industrial Applications (MAREX)
Kiuru, P. (Annan), Lipiäinen, T. (Annan), Tammela, P. (Annan), Montalvão, S. (Deltagare), Lillsunde, K.-E. (Deltagare), Vuorela, H. (Annan) & Yli-Kauhaluoma, J. (Annan)
01/08/2010 → 31/07/2014
Projekt: Forskningsprojekt

Citera det här

Skok, Ž., Barančoková, M., Benek, O., Cruz, C. D., Tammela, P., Tomašič, T., Zidar, N., Mašič, L. P., Zega, A., Stevenson, C. E. M., Mundy, J. E. A., Lawson, D. M., Maxwell, A., Kikelj, D., & Ilaš, J. (2020). Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors. ACS Medicinal Chemistry Letters, 11(12), 2433-2440. https://doi.org/10.1021/acsmedchemlett.0c00416

@article{d3708b4e5bc1469582fc84d142763631,

title = "Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors",

keywords = "317 Pharmacy, DNA gyrase, topoisomerase IV, GyrB, ParE, antibacterial, benzothiazole, ANTIBACTERIAL ACTIVITY, N-PHENYLINDOLAMIDES, ATPASE INHIBITORS, DRUG DISCOVERY, KIBDELOMYCIN, N-PHENYL-4,5-DIBROMOPYRROLAMIDES, TRANSLOCATION, AMYCOLAMICIN, CHALLENGES, RESISTANCE, DNA gyrase, topoisomerase IV, GyrB, ParE, antibacterial, benzothiazole, ANTIBACTERIAL ACTIVITY, N-PHENYLINDOLAMIDES, ATPASE INHIBITORS, DRUG DISCOVERY, KIBDELOMYCIN, N-PHENYL-4,5-DIBROMOPYRROLAMIDES, TRANSLOCATION, AMYCOLAMICIN, CHALLENGES, RESISTANCE",

author = "{\v Z}iga Skok and Michaela Baran{\v c}okov{\'a} and Ond{\v r}ej Benek and Cruz, {Cristina Durante} and P{\"a}ivi Tammela and Tihomir Toma{\v s}i{\v c} and Nace Zidar and Ma{\v s}i{\v c}, {Lucija Peterlin} and Anamarija Zega and Stevenson, {Clare E. M.} and Mundy, {Julia E. A.} and Lawson, {David M.} and Anthony Maxwell and Danijel Kikelj and Janez Ila{\v s}",

note = "doi: 10.1021/acsmedchemlett.0c00416",

year = "2020",

month = dec,

day = "10",

doi = "10.1021/acsmedchemlett.0c00416",

language = "English",

volume = "11",

pages = "2433--2440",

journal = "ACS Medicinal Chemistry Letters",

issn = "1948-5875",

publisher = "American Chemical Society",

number = "12",

}

Skok, Ž, Barančoková, M, Benek, O, Cruz, CD , Tammela, P, Tomašič, T, Zidar, N, Mašič, LP, Zega, A, Stevenson, CEM, Mundy, JEA, Lawson, DM, Maxwell, A, Kikelj, D & Ilaš, J 2020, 'Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors', ACS Medicinal Chemistry Letters, vol. 11, nr. 12, s. 2433-2440. https://doi.org/10.1021/acsmedchemlett.0c00416

TY - JOUR

T1 - Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

AU - Skok, Žiga

AU - Barančoková, Michaela

AU - Benek, Ondřej

AU - Cruz, Cristina Durante

AU - Tammela, Päivi

AU - Tomašič, Tihomir

AU - Zidar, Nace

AU - Mašič, Lucija Peterlin

AU - Zega, Anamarija

AU - Stevenson, Clare E. M.

AU - Mundy, Julia E. A.

AU - Lawson, David M.

AU - Maxwell, Anthony

AU - Kikelj, Danijel

AU - Ilaš, Janez

N1 - doi: 10.1021/acsmedchemlett.0c00416

PY - 2020/12/10

Y1 - 2020/12/10

KW - 317 Pharmacy

KW - DNA gyrase

KW - topoisomerase IV

KW - GyrB

KW - ParE

KW - antibacterial

KW - benzothiazole

KW - ANTIBACTERIAL ACTIVITY

KW - N-PHENYLINDOLAMIDES

KW - ATPASE INHIBITORS

KW - DRUG DISCOVERY

KW - KIBDELOMYCIN

KW - N-PHENYL-4,5-DIBROMOPYRROLAMIDES

KW - TRANSLOCATION

KW - AMYCOLAMICIN

KW - CHALLENGES

KW - RESISTANCE

KW - DNA gyrase

KW - topoisomerase IV

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KW - ParE

KW - antibacterial

KW - benzothiazole

KW - ANTIBACTERIAL ACTIVITY

KW - N-PHENYLINDOLAMIDES

KW - ATPASE INHIBITORS

KW - DRUG DISCOVERY

KW - KIBDELOMYCIN

KW - N-PHENYL-4,5-DIBROMOPYRROLAMIDES

KW - TRANSLOCATION

KW - AMYCOLAMICIN

KW - CHALLENGES

KW - RESISTANCE

U2 - 10.1021/acsmedchemlett.0c00416

DO - 10.1021/acsmedchemlett.0c00416

M3 - Article

SN - 1948-5875

VL - 11

SP - 2433

EP - 2440

JO - ACS Medicinal Chemistry Letters

JF - ACS Medicinal Chemistry Letters

IS - 12

ER -

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

Vetenskapsgrenar

Åtkomst av dokument

Projekt

EC-FP7-KBBE-2009-3-2-01-245137: Exploring Marine Resources for Bioactive Compounds: From Discovery to Sustainable Production and Industrial Applications (MAREX)

Citera det här