Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

Satu Lehti; Su D. Nguyen; Ilya Belevich; Helena Vihinen; Hanna M. Heikkilä; Rabah Soliymani; Reijo Käkelä; Jani Saksi; Matti Jauhiainen; Gregory A. Grabowski; Outi Kummu; Sohvi Hörkkö; Marc Baumann; Perttu J. Lindsberg; Eija Jokitalo; Petri T. Kovanen; Katariina Öörni

doi:10.1016/j.ajpath.2017.09.019

Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

Satu Lehti, Su D. Nguyen, Ilya Belevich, Helena Vihinen, Hanna M. Heikkilä, Rabah Soliymani, Reijo Käkelä, Jani Saksi, Matti Jauhiainen, Gregory A. Grabowski, Outi Kummu, Sohvi Hörkkö, Marc Baumann, Perttu J. Lindsberg, Eija Jokitalo, Petri T. Kovanen, Katariina Öörni

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	The American Journal of Pathology
Volym	188
Nummer	2
Sidor (från-till)	525-538
Antal sidor	14
ISSN	0002-9440
DOI	https://doi.org/10.1016/j.ajpath.2017.09.019
Status	Publicerad - feb. 2018
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper

Åtkomst av dokument

10.1016/j.ajpath.2017.09.019

Lehti 2018Accepterat manuskript från författare, 3,85 MBLicens: CC BY-NC-ND

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Lehti, S., Nguyen, S. D., Belevich, I., Vihinen, H., Heikkilä, H. M., Soliymani, R., Käkelä, R., Saksi, J., Jauhiainen, M., Grabowski, G. A., Kummu, O., Hörkkö, S., Baumann, M., Lindsberg, P. J., Jokitalo, E., Kovanen, P. T., & Öörni, K. (2018). Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties. The American Journal of Pathology, 188(2), 525-538. https://doi.org/10.1016/j.ajpath.2017.09.019

@article{2e46a5928bde45ce8903133b6bc0d24b,

title = "Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties",

keywords = "LOW-DENSITY-LIPOPROTEIN, HUMAN ATHEROSCLEROTIC LESIONS, NLRP3 INFLAMMASOME ACTIVATION, FOAM CELL-FORMATION, SECRETORY SPHINGOMYELINASE, CHOLESTEROL CRYSTALS, PROTEOGLYCAN-BINDING, ELECTRON-MICROSCOPY, HUMAN MONOCYTES, DEFICIENT MICE, 3111 Biomedicine",

author = "Satu Lehti and Nguyen, \{Su D.\} and Ilya Belevich and Helena Vihinen and Heikkil{\"a}, \{Hanna M.\} and Rabah Soliymani and Reijo K{\"a}kel{\"a} and Jani Saksi and Matti Jauhiainen and Grabowski, \{Gregory A.\} and Outi Kummu and Sohvi H{\"o}rkk{\"o} and Marc Baumann and Lindsberg, \{Perttu J.\} and Eija Jokitalo and Kovanen, \{Petri T.\} and Katariina {\"O}{\"o}rni",

year = "2018",

month = feb,

doi = "10.1016/j.ajpath.2017.09.019",

language = "English",

volume = "188",

pages = "525--538",

journal = "The American Journal of Pathology",

issn = "0002-9440",

publisher = "Elsevier Inc. ",

number = "2",

}

Lehti, S, Nguyen, SD, Belevich, I , Vihinen, H, Heikkilä, HM, Soliymani, R , Käkelä, R, Saksi, J, Jauhiainen, M, Grabowski, GA, Kummu, O, Hörkkö, S, Baumann, M , Lindsberg, PJ , Jokitalo, E , Kovanen, PT & Öörni, K 2018, 'Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties', The American Journal of Pathology, vol. 188, nr. 2, s. 525-538. https://doi.org/10.1016/j.ajpath.2017.09.019

TY - JOUR

T1 - Extracellular Lipids Accumulate in Human Carotid Arteries as Distinct Three-Dimensional Structures and Have Proinflammatory Properties

AU - Lehti, Satu

AU - Nguyen, Su D.

AU - Belevich, Ilya

AU - Vihinen, Helena

AU - Heikkilä, Hanna M.

AU - Soliymani, Rabah

AU - Käkelä, Reijo

AU - Saksi, Jani

AU - Jauhiainen, Matti

AU - Grabowski, Gregory A.

AU - Kummu, Outi

AU - Hörkkö, Sohvi

AU - Baumann, Marc

AU - Lindsberg, Perttu J.

AU - Jokitalo, Eija

AU - Kovanen, Petri T.

AU - Öörni, Katariina

PY - 2018/2

Y1 - 2018/2

KW - LOW-DENSITY-LIPOPROTEIN

KW - HUMAN ATHEROSCLEROTIC LESIONS

KW - NLRP3 INFLAMMASOME ACTIVATION

KW - FOAM CELL-FORMATION

KW - SECRETORY SPHINGOMYELINASE

KW - CHOLESTEROL CRYSTALS

KW - PROTEOGLYCAN-BINDING

KW - ELECTRON-MICROSCOPY

KW - HUMAN MONOCYTES

KW - DEFICIENT MICE

KW - 3111 Biomedicine

UR - https://www.scopus.com/pages/publications/85044605874

U2 - 10.1016/j.ajpath.2017.09.019

DO - 10.1016/j.ajpath.2017.09.019

M3 - Article

SN - 0002-9440

VL - 188

SP - 525

EP - 538

JO - The American Journal of Pathology

JF - The American Journal of Pathology

IS - 2

ER -