Genetic drivers and cellular selection of female mosaic X chromosome loss

FinnGen; Estonian Biobank Research Team; Breast Cancer Association Consortium; Million Veteran Program; Aoxing Liu; Giulio Genovese; Yajie Zhao; Matti Pirinen; Seyedeh M. Zekavat; Katherine A. Kentistou; Zhiyu Yang; Kai Yu; Caitlyn Vlasschaert; Xiaoxi Liu; Derek W. Brown; Georgi Hudjashov; Bryan R. Gorman; Joe Dennis; Weiyin Zhou; Yukihide Momozawa; Saiju Pyarajan; Valdislav Tuzov; Fanny Dhelia Pajuste; Mervi Aavikko; Timo P. Sipilä; Awaisa Ghazal; Wen Yi Huang; Neal D. Freedman; Lei Song; Eugene J. Gardner; Vijay G. Sankaran; Aarno Palotie; Hanna M. Ollila; Taru Tukiainen; Stephen J. Chanock; Reedik Mägi; Pradeep Natarajan; Mark J. Daly; Alexander Bick; Steven A. McCarroll; Chikashi Terao; Po Ru Loh; Andrea Ganna; John R.B. Perry; Mitchell J. Machiela

doi:10.1038/s41586-024-07533-7

Genetic drivers and cellular selection of female mosaic X chromosome loss

FinnGen, Estonian Biobank Research Team, Breast Cancer Association Consortium, Million Veteran Program, Aoxing Liu, Giulio Genovese, Yajie Zhao, Matti Pirinen, Seyedeh M. Zekavat, Katherine A. Kentistou, Zhiyu Yang, Kai Yu, Caitlyn Vlasschaert, Xiaoxi Liu, Derek W. Brown, Georgi Hudjashov, Bryan R. Gorman, Joe Dennis, Weiyin Zhou, Yukihide MomozawaSaiju Pyarajan, Valdislav Tuzov, Fanny Dhelia Pajuste, Mervi Aavikko, Timo P. Sipilä, Awaisa Ghazal, Wen Yi Huang, Neal D. Freedman, Lei Song, Eugene J. Gardner, Vijay G. Sankaran, Aarno Palotie, Hanna M. Ollila, Taru Tukiainen, Stephen J. Chanock, Reedik Mägi, Pradeep Natarajan, Mark J. Daly, Alexander Bick, Steven A. McCarroll, Chikashi Terao, Po Ru Loh, Andrea Ganna, John R.B. Perry, Mitchell J. Machiela

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Nature
Volym	631
Nummer	8019
Sidor (från-till)	134-141
Antal sidor	23
ISSN	0028-0836
DOI	https://doi.org/10.1038/s41586-024-07533-7
Status	Publicerad - 12 juni 2024
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Bibliografisk information

Publisher Copyright:
© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

Vetenskapsgrenar

3111 Biomedicinska vetenskaper
1184 Genetik, utvecklingsbiologi, fysiologi

Åtkomst av dokument

10.1038/s41586-024-07533-7

Citera det här

FinnGen, Estonian Biobank Research Team, Breast Cancer Association Consortium, Million Veteran Program, Liu, A., Genovese, G., Zhao, Y., Pirinen, M., Zekavat, S. M., Kentistou, K. A., Yang, Z., Yu, K., Vlasschaert, C., Liu, X., Brown, D. W., Hudjashov, G., Gorman, B. R., Dennis, J., Zhou, W., ... Machiela, M. J. (2024). Genetic drivers and cellular selection of female mosaic X chromosome loss. Nature, 631(8019), 134-141. https://doi.org/10.1038/s41586-024-07533-7

@article{838c88965884404098be09abbca1e181,

title = "Genetic drivers and cellular selection of female mosaic X chromosome loss",

keywords = "3111 Biomedicine, 1184 Genetics, developmental biology, physiology",

author = "FinnGen and {Estonian Biobank Research Team} and {Breast Cancer Association Consortium} and {Million Veteran Program} and Aoxing Liu and Giulio Genovese and Yajie Zhao and Matti Pirinen and Zekavat, {Seyedeh M.} and Kentistou, {Katherine A.} and Zhiyu Yang and Kai Yu and Caitlyn Vlasschaert and Xiaoxi Liu and Brown, {Derek W.} and Georgi Hudjashov and Gorman, {Bryan R.} and Joe Dennis and Weiyin Zhou and Yukihide Momozawa and Saiju Pyarajan and Valdislav Tuzov and Pajuste, {Fanny Dhelia} and Mervi Aavikko and Sipil{\"a}, {Timo P.} and Awaisa Ghazal and Huang, {Wen Yi} and Freedman, {Neal D.} and Lei Song and Gardner, {Eugene J.} and Sankaran, {Vijay G.} and Aarno Palotie and Ollila, {Hanna M.} and Taru Tukiainen and Chanock, {Stephen J.} and Reedik M{\"a}gi and Pradeep Natarajan and Daly, {Mark J.} and Alexander Bick and McCarroll, {Steven A.} and Chikashi Terao and Loh, {Po Ru} and Andrea Ganna and Perry, {John R.B.} and Machiela, {Mitchell J.}",

note = "Correction: DOI 10.1038/s41586-024-08215-0 Publisher Copyright: {\textcopyright} 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.",

year = "2024",

month = jun,

day = "12",

doi = "10.1038/s41586-024-07533-7",

language = "English",

volume = "631",

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journal = "Nature",

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FinnGen, Estonian Biobank Research Team, Breast Cancer Association Consortium, Million Veteran Program, Liu, A, Genovese, G, Zhao, Y, Pirinen, M, Zekavat, SM, Kentistou, KA, Yang, Z, Yu, K, Vlasschaert, C, Liu, X, Brown, DW, Hudjashov, G, Gorman, BR, Dennis, J, Zhou, W, Momozawa, Y, Pyarajan, S, Tuzov, V, Pajuste, FD, Aavikko, M , Sipilä, TP , Ghazal, A, Huang, WY, Freedman, ND, Song, L, Gardner, EJ, Sankaran, VG, Palotie, A , Ollila, HM , Tukiainen, T, Chanock, SJ, Mägi, R, Natarajan, P, Daly, MJ, Bick, A, McCarroll, SA, Terao, C, Loh, PR, Ganna, A, Perry, JRB & Machiela, MJ 2024, 'Genetic drivers and cellular selection of female mosaic X chromosome loss', Nature, vol. 631, nr. 8019, s. 134-141. https://doi.org/10.1038/s41586-024-07533-7

TY - JOUR

T1 - Genetic drivers and cellular selection of female mosaic X chromosome loss

AU - FinnGen

AU - Estonian Biobank Research Team

AU - Breast Cancer Association Consortium

AU - Million Veteran Program

AU - Liu, Aoxing

AU - Genovese, Giulio

AU - Zhao, Yajie

AU - Pirinen, Matti

AU - Zekavat, Seyedeh M.

AU - Kentistou, Katherine A.

AU - Yang, Zhiyu

AU - Yu, Kai

AU - Vlasschaert, Caitlyn

AU - Liu, Xiaoxi

AU - Brown, Derek W.

AU - Hudjashov, Georgi

AU - Gorman, Bryan R.

AU - Dennis, Joe

AU - Zhou, Weiyin

AU - Momozawa, Yukihide

AU - Pyarajan, Saiju

AU - Tuzov, Valdislav

AU - Pajuste, Fanny Dhelia

AU - Aavikko, Mervi

AU - Sipilä, Timo P.

AU - Ghazal, Awaisa

AU - Huang, Wen Yi

AU - Freedman, Neal D.

AU - Song, Lei

AU - Gardner, Eugene J.

AU - Sankaran, Vijay G.

AU - Palotie, Aarno

AU - Ollila, Hanna M.

AU - Tukiainen, Taru

AU - Chanock, Stephen J.

AU - Mägi, Reedik

AU - Natarajan, Pradeep

AU - Daly, Mark J.

AU - Bick, Alexander

AU - McCarroll, Steven A.

AU - Terao, Chikashi

AU - Loh, Po Ru

AU - Ganna, Andrea

AU - Perry, John R.B.

AU - Machiela, Mitchell J.

PY - 2024/6/12

Y1 - 2024/6/12

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/s41586-024-07533-7

DO - 10.1038/s41586-024-07533-7

M3 - Article

C2 - 38867047

AN - SCOPUS:85197973294

SN - 0028-0836

VL - 631

SP - 134

EP - 141

JO - Nature

JF - Nature

IS - 8019

ER -