Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity

Jurgita Paukštytė; Rosa María López Cabezas; Yuehan Feng; Kai Tong; Daniela Schnyder; Ellinoora Elomaa; Pavlina Gregorova; Matteo Doudin; Meeri Särkkä; Jesse Sarameri; Alice Lippi; Helena Vihinen; Juhana Juutila; Anni Nieminen; Petri Törönen; Liisa Holm; Eija Jokitalo; Anita Krisko; Juha Huiskonen; L. Peter Sarin; Ville Hietakangas; Paola Picotti; Yves Barral; Juha Saarikangas

doi:10.1016/j.molcel.2023.08.015

Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity

Jurgita Paukštytė, Rosa María López Cabezas, Yuehan Feng, Kai Tong, Daniela Schnyder, Ellinoora Elomaa, Pavlina Gregorova, Matteo Doudin, Meeri Särkkä, Jesse Sarameri, Alice Lippi, Helena Vihinen, Juhana Juutila, Anni Nieminen, Petri Törönen, Liisa Holm, Eija Jokitalo, Anita Krisko, Juha Huiskonen, L. Peter SarinVille Hietakangas, Paola Picotti, Yves Barral, Juha Saarikangas

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Molecular Cell
Volym	83
Nummer	18
Sidor (från-till)	3360-3376
ISSN	1097-2765
DOI	https://doi.org/10.1016/j.molcel.2023.08.015
Status	Publicerad - 21 sep. 2023
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Bibliografisk information

Publisher Copyright:
© 2023 The Authors

Vetenskapsgrenar

1182 Biokemi, cell- och molekylärbiologi

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10.1016/j.molcel.2023.08.015Licens: CC BY

GlobalSlutlig publicerad version, 5,4 MBLicens: CC BY

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Paukštytė, J., López Cabezas, R. M., Feng, Y., Tong, K., Schnyder, D., Elomaa, E., Gregorova, P., Doudin, M., Särkkä, M., Sarameri, J., Lippi, A., Vihinen, H., Juutila, J., Nieminen, A., Törönen, P., Holm, L., Jokitalo, E., Krisko, A., Huiskonen, J., ... Saarikangas, J. (2023). Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity. Molecular Cell, 83(18), 3360-3376. https://doi.org/10.1016/j.molcel.2023.08.015

@article{15e02d4624a44390850265658c06f775,

title = "Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity",

keywords = "aging, amino acid, functional proteomics, limited proteolysis, mass spectrometry, polymerization, self-assembly, structural change, structural proteomics, yeast, 1182 Biochemistry, cell and molecular biology",

author = "Jurgita Pauk{\v s}tytė and {L{\'o}pez Cabezas}, {Rosa Mar{\'i}a} and Yuehan Feng and Kai Tong and Daniela Schnyder and Ellinoora Elomaa and Pavlina Gregorova and Matteo Doudin and Meeri S{\"a}rkk{\"a} and Jesse Sarameri and Alice Lippi and Helena Vihinen and Juhana Juutila and Anni Nieminen and Petri T{\"o}r{\"o}nen and Liisa Holm and Eija Jokitalo and Anita Krisko and Juha Huiskonen and Sarin, {L. Peter} and Ville Hietakangas and Paola Picotti and Yves Barral and Juha Saarikangas",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors",

year = "2023",

month = sep,

day = "21",

doi = "10.1016/j.molcel.2023.08.015",

language = "English",

volume = "83",

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Paukštytė, J, López Cabezas, RM, Feng, Y, Tong, K, Schnyder, D, Elomaa, E , Gregorova, P, Doudin, M, Särkkä, M, Sarameri, J, Lippi, A, Vihinen, H, Juutila, J, Nieminen, A , Törönen, P , Holm, L , Jokitalo, E, Krisko, A, Huiskonen, J , Sarin, LP , Hietakangas, V, Picotti, P, Barral, Y & Saarikangas, J 2023, 'Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity', Molecular Cell, vol. 83, nr. 18, s. 3360-3376. https://doi.org/10.1016/j.molcel.2023.08.015

TY - JOUR

T1 - Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity

AU - Paukštytė, Jurgita

AU - López Cabezas, Rosa María

AU - Feng, Yuehan

AU - Tong, Kai

AU - Schnyder, Daniela

AU - Elomaa, Ellinoora

AU - Gregorova, Pavlina

AU - Doudin, Matteo

AU - Särkkä, Meeri

AU - Sarameri, Jesse

AU - Lippi, Alice

AU - Vihinen, Helena

AU - Juutila, Juhana

AU - Nieminen, Anni

AU - Törönen, Petri

AU - Holm, Liisa

AU - Jokitalo, Eija

AU - Krisko, Anita

AU - Huiskonen, Juha

AU - Sarin, L. Peter

AU - Hietakangas, Ville

AU - Picotti, Paola

AU - Barral, Yves

AU - Saarikangas, Juha

PY - 2023/9/21

Y1 - 2023/9/21

KW - aging

KW - amino acid

KW - functional proteomics

KW - limited proteolysis

KW - mass spectrometry

KW - polymerization

KW - self-assembly

KW - structural change

KW - structural proteomics

KW - yeast

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.molcel.2023.08.015

DO - 10.1016/j.molcel.2023.08.015

M3 - Article

C2 - 37699397

AN - SCOPUS:85171153307

SN - 1097-2765

VL - 83

SP - 3360

EP - 3376

JO - Molecular Cell

JF - Molecular Cell

IS - 18

ER -