Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

Eleonora Leggiero, Giuseppe Labruna, Laura Iaffaldano, Barbara Lombardo, Adelaide Greco, Dario Fiorenza, Matteo Gramanzini, Donatella Montanaro, Alfonso Baldi, Vincenzo Cerullo, Lucia Sacchetti, Lucio Pastore

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Originalspråkengelska
TidskriftGene Therapy (Basingstoke)
Volym26
Utgåva3-4
Sidor (från-till)121-130
Antal sidor10
ISSN0969-7128
DOI
StatusPublicerad - apr 2019
MoE-publikationstypA1 Tidskriftsartikel-refererad

Vetenskapsgrenar

  • 1182 Biokemi, cell- och molekylärbiologi
  • 1183 Växtbiologi, mikrobiologi, virologi
  • 1184 Genetik, utvecklingsbiologi, fysiologi

Citera det här

Leggiero, Eleonora ; Labruna, Giuseppe ; Iaffaldano, Laura ; Lombardo, Barbara ; Greco, Adelaide ; Fiorenza, Dario ; Gramanzini, Matteo ; Montanaro, Donatella ; Baldi, Alfonso ; Cerullo, Vincenzo ; Sacchetti, Lucia ; Pastore, Lucio. / Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice. I: Gene Therapy (Basingstoke). 2019 ; Vol. 26, Nr. 3-4. s. 121-130.
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title = "Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice",
keywords = "A-I, FAMILIAL HYPERCHOLESTEROLEMIA, FUNCTIONAL-EVALUATION, IMMUNE-RESPONSES, THERAPEUTIC TOOL, FUSION PROTEIN, AAV-VECTORS, MOUSE MODEL, EXPRESSION, LIVER, 1182 Biochemistry, cell and molecular biology, 1183 Plant biology, microbiology, virology, 1184 Genetics, developmental biology, physiology",
author = "Eleonora Leggiero and Giuseppe Labruna and Laura Iaffaldano and Barbara Lombardo and Adelaide Greco and Dario Fiorenza and Matteo Gramanzini and Donatella Montanaro and Alfonso Baldi and Vincenzo Cerullo and Lucia Sacchetti and Lucio Pastore",
year = "2019",
month = "4",
doi = "10.1038/s41434-019-0061-z",
language = "English",
volume = "26",
pages = "121--130",
journal = "Gene Therapy (Basingstoke)",
issn = "0969-7128",
publisher = "Nature Publishing Group",
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}

Leggiero, E, Labruna, G, Iaffaldano, L, Lombardo, B, Greco, A, Fiorenza, D, Gramanzini, M, Montanaro, D, Baldi, A, Cerullo, V, Sacchetti, L & Pastore, L 2019, 'Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice', Gene Therapy (Basingstoke), vol. 26, nr. 3-4, s. 121-130. https://doi.org/10.1038/s41434-019-0061-z

Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice. / Leggiero, Eleonora; Labruna, Giuseppe; Iaffaldano, Laura; Lombardo, Barbara; Greco, Adelaide; Fiorenza, Dario; Gramanzini, Matteo; Montanaro, Donatella; Baldi, Alfonso; Cerullo, Vincenzo; Sacchetti, Lucia; Pastore, Lucio.

I: Gene Therapy (Basingstoke), Vol. 26, Nr. 3-4, 04.2019, s. 121-130.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

TY - JOUR

T1 - Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

AU - Leggiero, Eleonora

AU - Labruna, Giuseppe

AU - Iaffaldano, Laura

AU - Lombardo, Barbara

AU - Greco, Adelaide

AU - Fiorenza, Dario

AU - Gramanzini, Matteo

AU - Montanaro, Donatella

AU - Baldi, Alfonso

AU - Cerullo, Vincenzo

AU - Sacchetti, Lucia

AU - Pastore, Lucio

PY - 2019/4

Y1 - 2019/4

KW - A-I

KW - FAMILIAL HYPERCHOLESTEROLEMIA

KW - FUNCTIONAL-EVALUATION

KW - IMMUNE-RESPONSES

KW - THERAPEUTIC TOOL

KW - FUSION PROTEIN

KW - AAV-VECTORS

KW - MOUSE MODEL

KW - EXPRESSION

KW - LIVER

KW - 1182 Biochemistry, cell and molecular biology

KW - 1183 Plant biology, microbiology, virology

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/s41434-019-0061-z

DO - 10.1038/s41434-019-0061-z

M3 - Article

VL - 26

SP - 121

EP - 130

JO - Gene Therapy (Basingstoke)

JF - Gene Therapy (Basingstoke)

SN - 0969-7128

IS - 3-4

ER -