High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

Paul D. Andrews; Melissa Becroft; Anders Aspegren; Jane Gilmour; Martyn J. James; Scott McRae; Robert Kime; Robert W. Allcock; Achamma Abraham; Zhong Jiang; Raimund Strehl; Joanne C. Mountford; Graeme Milligan; Miles D. Houslay; David R. Adams; Julie A. Frearson

doi:10.1042/BJ20101022

High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

Paul D. Andrews, Melissa Becroft, Anders Aspegren, Jane Gilmour, Martyn J. James, Scott McRae, Robert Kime, Robert W. Allcock, Achamma Abraham, Zhong Jiang, Raimund Strehl, Joanne C. Mountford, Graeme Milligan, Miles D. Houslay, David R. Adams, Julie A. Frearson

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Biochemical Journal
Volym	432
Nummer	1
Sidor (från-till)	21-33
Antal sidor	13
ISSN	0264-6021
DOI	https://doi.org/10.1042/BJ20101022
Status	Publicerad - 15 nov. 2010
Externt publicerad	Ja
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Åtkomst av dokument

10.1042/BJ20101022

Citera det här

Andrews, P. D., Becroft, M., Aspegren, A., Gilmour, J., James, M. J., McRae, S., Kime, R., Allcock, R. W., Abraham, A., Jiang, Z., Strehl, R., Mountford, J. C., Milligan, G., Houslay, M. D., Adams, D. R., & Frearson, J. A. (2010). High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules. Biochemical Journal, 432(1), 21-33. https://doi.org/10.1042/BJ20101022

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title = "High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules",

keywords = "drug discovery, high-content screening, human embryonic stem cell, pinacidil, protein kinase inhibitor, Rho-associated kinase (ROCK), Y-27632, RHO-KINASE, ROCK INHIBITOR, SELF-RENEWAL, SRC FAMILY, MECHANISM, GROWTH, RECEPTOR, DESIGN",

author = "Andrews, {Paul D.} and Melissa Becroft and Anders Aspegren and Jane Gilmour and James, {Martyn J.} and Scott McRae and Robert Kime and Allcock, {Robert W.} and Achamma Abraham and Zhong Jiang and Raimund Strehl and Mountford, {Joanne C.} and Graeme Milligan and Houslay, {Miles D.} and Adams, {David R.} and Frearson, {Julie A.}",

year = "2010",

month = nov,

day = "15",

doi = "10.1042/BJ20101022",

language = "English",

volume = "432",

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journal = "Biochemical Journal",

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Andrews, PD, Becroft, M, Aspegren, A, Gilmour, J, James, MJ, McRae, S, Kime, R, Allcock, RW, Abraham, A, Jiang, Z, Strehl, R, Mountford, JC, Milligan, G, Houslay, MD, Adams, DR & Frearson, JA 2010, 'High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules', Biochemical Journal, vol. 432, nr. 1, s. 21-33. https://doi.org/10.1042/BJ20101022

TY - JOUR

T1 - High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules

AU - Andrews, Paul D.

AU - Becroft, Melissa

AU - Aspegren, Anders

AU - Gilmour, Jane

AU - James, Martyn J.

AU - McRae, Scott

AU - Kime, Robert

AU - Allcock, Robert W.

AU - Abraham, Achamma

AU - Jiang, Zhong

AU - Strehl, Raimund

AU - Mountford, Joanne C.

AU - Milligan, Graeme

AU - Houslay, Miles D.

AU - Adams, David R.

AU - Frearson, Julie A.

PY - 2010/11/15

Y1 - 2010/11/15

KW - drug discovery

KW - high-content screening

KW - human embryonic stem cell

KW - pinacidil

KW - protein kinase inhibitor

KW - Rho-associated kinase (ROCK)

KW - Y-27632

KW - RHO-KINASE

KW - ROCK INHIBITOR

KW - SELF-RENEWAL

KW - SRC FAMILY

KW - MECHANISM

KW - GROWTH

KW - RECEPTOR

KW - DESIGN

U2 - 10.1042/BJ20101022

DO - 10.1042/BJ20101022

M3 - Article

SN - 0264-6021

VL - 432

SP - 21

EP - 33

JO - Biochemical Journal

JF - Biochemical Journal

IS - 1

ER -