High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

Katja Tuomainen; Aini Hyytiäinen; Ahmed Al-Samadi; Philipp Ianevski; Aleksandr Ianevski; Swapnil Potdar; Laura Turunen; Jani Saarela; Sergey Kuznetsov; Wafa Wahbi; Maija Risteli; Antti Mäkitie; Outi Monni; Tuula Salo

doi:10.1038/s41598-021-94259-5

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

Katja Tuomainen, Aini Hyytiäinen, Ahmed Al-Samadi, Philipp Ianevski, Aleksandr Ianevski, Swapnil Potdar, Laura Turunen, Jani Saarela, Sergey Kuznetsov, Wafa Wahbi, Maija Risteli, Antti Mäkitie, Outi Monni, Tuula Salo

Forskningsoutput: Tidskriftsbidrag › Artikel › Peer review

Originalspråk	engelska
Artikelnummer	14755
Tidskrift	Scientific Reports
Volym	11
Antal sidor	10
ISSN	2045-2322
DOI	https://doi.org/10.1038/s41598-021-94259-5
Status	Publicerad - 20 jul 2021
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3122 Cancersjukdomar

Åtkomst av dokument

10.1038/s41598-021-94259-5Licens: CC BY

s41598-021-94259-5Slutlig publicerad version, 3,98 MBLicens: CC BY

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Tuomainen, K., Hyytiäinen, A., Al-Samadi, A., Ianevski, P., Ianevski, A., Potdar, S., Turunen, L., Saarela, J., Kuznetsov, S., Wahbi, W., Risteli, M., Mäkitie, A., Monni, O., & Salo, T. (2021). High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma. Scientific Reports, 11, [14755]. https://doi.org/10.1038/s41598-021-94259-5

Tuomainen, Katja ; Hyytiäinen, Aini ; Al-Samadi, Ahmed ; Ianevski, Philipp ; Ianevski, Aleksandr ; Potdar, Swapnil ; Turunen, Laura ; Saarela, Jani ; Kuznetsov, Sergey ; Wahbi, Wafa ; Risteli, Maija ; Mäkitie, Antti ; Monni, Outi ; Salo, Tuula. / High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma. I: Scientific Reports. 2021 ; Vol. 11.

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title = "High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma",

keywords = "CANCER, COMBINATION, 3122 Cancers",

author = "Katja Tuomainen and Aini Hyyti{\"a}inen and Ahmed Al-Samadi and Philipp Ianevski and Aleksandr Ianevski and Swapnil Potdar and Laura Turunen and Jani Saarela and Sergey Kuznetsov and Wafa Wahbi and Maija Risteli and Antti M{\"a}kitie and Outi Monni and Tuula Salo",

year = "2021",

month = jul,

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doi = "10.1038/s41598-021-94259-5",

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Tuomainen, K, Hyytiäinen, A, Al-Samadi, A, Ianevski, P, Ianevski, A , Potdar, S , Turunen, L , Saarela, J , Kuznetsov, S , Wahbi, W, Risteli, M, Mäkitie, A , Monni, O & Salo, T 2021, 'High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma', Scientific Reports, vol. 11, 14755. https://doi.org/10.1038/s41598-021-94259-5

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma. / Tuomainen, Katja; Hyytiäinen, Aini; Al-Samadi, Ahmed; Ianevski, Philipp; Ianevski, Aleksandr ; Potdar, Swapnil ; Turunen, Laura ; Saarela, Jani ; Kuznetsov, Sergey ; Wahbi, Wafa; Risteli, Maija; Mäkitie, Antti ; Monni, Outi ; Salo, Tuula.

I: Scientific Reports, Vol. 11, 14755, 20.07.2021.

Forskningsoutput: Tidskriftsbidrag › Artikel › Peer review

TY - JOUR

T1 - High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

AU - Tuomainen, Katja

AU - Hyytiäinen, Aini

AU - Al-Samadi, Ahmed

AU - Ianevski, Philipp

AU - Ianevski, Aleksandr

AU - Potdar, Swapnil

AU - Turunen, Laura

AU - Saarela, Jani

AU - Kuznetsov, Sergey

AU - Wahbi, Wafa

AU - Risteli, Maija

AU - Mäkitie, Antti

AU - Monni, Outi

AU - Salo, Tuula

PY - 2021/7/20

Y1 - 2021/7/20

KW - CANCER

KW - COMBINATION

KW - 3122 Cancers

U2 - 10.1038/s41598-021-94259-5

DO - 10.1038/s41598-021-94259-5

M3 - Article

VL - 11

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 14755

ER -