Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure

Stanislav Kalinin; Annika Valtari; Marika Ruponen; Elisa Toropainen; Alexander Kovalenko; Alessio Nocentini; Maxim Gureev; Dmitry Dar'in; Arto Urtti; Claudiu T. Supuran; Mikhail Krasavin

doi:10.1016/j.bmc.2019.115086

Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure

Stanislav Kalinin
, Annika Valtari
, Marika Ruponen
, Elisa Toropainen
, Alexander Kovalenko
, Alessio Nocentini
, Maxim Gureev
, Dmitry Dar'in
, Arto Urtti
, Claudiu T. Supuran
, Mikhail Krasavin

Avdelningen för farmaceutiska biovetenskaper

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	115086
Tidskrift	Bioorganic & Medicinal Chemistry
Volym	27
Nummer	21
Antal sidor	8
ISSN	0968-0896
DOI	https://doi.org/10.1016/j.bmc.2019.115086
Status	Publicerad - 1 nov. 2019
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

116 Kemi
1182 Biokemi, cell- och molekylärbiologi
317 Farmaci

Åtkomst av dokument

10.1016/j.bmc.2019.115086

Citera det här

Kalinin, S., Valtari, A., Ruponen, M., Toropainen, E., Kovalenko, A., Nocentini, A., Gureev, M., Dar'in, D., Urtti, A., Supuran, C. T., & Krasavin, M. (2019). Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure. Bioorganic & Medicinal Chemistry, 27(21), Artikel 115086. https://doi.org/10.1016/j.bmc.2019.115086

@article{2747e1c2bdda4e6f9fc22aabf124d301,

title = "Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure",

keywords = "Glaucoma, Intraocular pressure, Hydrophilicity, Intraocular delivery, Non-corneal absorption, Carbonic anhydrase inhibitors, QUANTITATIVE-EVALUATION, PICOMOLAR INHIBITORS, SYSTEMIC ABSORPTION, PILOCARPINE, PHARMACOTHERAPY, SULFONAMIDES, CONJUNCTIVA, PROTEIN, 116 Chemical sciences, 1182 Biochemistry, cell and molecular biology, 317 Pharmacy",

author = "Stanislav Kalinin and Annika Valtari and Marika Ruponen and Elisa Toropainen and Alexander Kovalenko and Alessio Nocentini and Maxim Gureev and Dmitry Dar'in and Arto Urtti and Supuran, \{Claudiu T.\} and Mikhail Krasavin",

year = "2019",

month = nov,

day = "1",

doi = "10.1016/j.bmc.2019.115086",

language = "English",

volume = "27",

journal = "Bioorganic \& Medicinal Chemistry",

issn = "0968-0896",

publisher = "Elsevier Ltd. ",

number = "21",

}

Kalinin, S, Valtari, A, Ruponen, M, Toropainen, E, Kovalenko, A, Nocentini, A, Gureev, M, Dar'in, D, Urtti, A, Supuran, CT & Krasavin, M 2019, 'Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure', Bioorganic & Medicinal Chemistry, vol. 27, nr. 21, 115086. https://doi.org/10.1016/j.bmc.2019.115086

TY - JOUR

T1 - Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure

AU - Kalinin, Stanislav

AU - Valtari, Annika

AU - Ruponen, Marika

AU - Toropainen, Elisa

AU - Kovalenko, Alexander

AU - Nocentini, Alessio

AU - Gureev, Maxim

AU - Dar'in, Dmitry

AU - Urtti, Arto

AU - Supuran, Claudiu T.

AU - Krasavin, Mikhail

PY - 2019/11/1

Y1 - 2019/11/1

KW - Glaucoma

KW - Intraocular pressure

KW - Hydrophilicity

KW - Intraocular delivery

KW - Non-corneal absorption

KW - Carbonic anhydrase inhibitors

KW - QUANTITATIVE-EVALUATION

KW - PICOMOLAR INHIBITORS

KW - SYSTEMIC ABSORPTION

KW - PILOCARPINE

KW - PHARMACOTHERAPY

KW - SULFONAMIDES

KW - CONJUNCTIVA

KW - PROTEIN

KW - 116 Chemical sciences

KW - 1182 Biochemistry, cell and molecular biology

KW - 317 Pharmacy

U2 - 10.1016/j.bmc.2019.115086

DO - 10.1016/j.bmc.2019.115086

M3 - Article

SN - 0968-0896

VL - 27

JO - Bioorganic & Medicinal Chemistry

JF - Bioorganic & Medicinal Chemistry

IS - 21

M1 - 115086

ER -