Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

Mikko Neuvonen; Päivi Hirvensalo; Aleksi Tornio; Brian Rago; Mark West; Sarah Lazzaro; Sumathy Mathialagan; Manthena Varma; Matthew A. Cerny; Chester Costales; Ragu Ramanathan; A. David Rodrigues; Mikko Niemi

doi:10.1002/cpt.2053

Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

Mikko Neuvonen, Päivi Hirvensalo, Aleksi Tornio, Brian Rago, Mark West, Sarah Lazzaro, Sumathy Mathialagan, Manthena Varma, Matthew A. Cerny, Chester Costales, Ragu Ramanathan, A. David Rodrigues, Mikko Niemi

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Clinical Pharmacology and Therapeutics
Antal sidor	12
ISSN	0009-9236
DOI	https://doi.org/10.1002/cpt.2053
Status	!!E-pub ahead of print - 18 okt. 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Åtkomst av dokument

10.1002/cpt.2053

Identification of Glycochenodeoxycholate 3‐O‐Glucuronide and Glycodeoxycholate 3‐O‐Glucuronide as Highly Sensitive and Specific OATP1B1 BiomarkersAccepterat manuskript från författare, 14,2 MB

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Neuvonen, M., Hirvensalo, P., Tornio, A., Rago, B., West, M., Lazzaro, S., Mathialagan, S., Varma, M., Cerny, M. A., Costales, C., Ramanathan, R., Rodrigues, A. D., & Niemi, M. (2020). Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers. Clinical Pharmacology and Therapeutics. https://doi.org/10.1002/cpt.2053

Neuvonen, Mikko ; Hirvensalo, Päivi ; Tornio, Aleksi ; Rago, Brian ; West, Mark ; Lazzaro, Sarah ; Mathialagan, Sumathy ; Varma, Manthena ; Cerny, Matthew A. ; Costales, Chester ; Ramanathan, Ragu ; Rodrigues, A. David ; Niemi, Mikko. / Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers. I: Clinical Pharmacology and Therapeutics. 2020.

@article{5baa484ecb9d4086ad5295681cf4ea48,

title = "Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers",

keywords = "ANION TRANSPORTING POLYPEPTIDE, POLYMORPHISM MARKEDLY AFFECTS, SLCO1B1 POLYMORPHISM, ENDOGENOUS BIOMARKERS, HAPLOTYPE RECONSTRUCTION, PLASMA-CONCENTRATIONS, CYNOMOLGUS MONKEYS, DRUG-INTERACTION, GENOME-WIDE, BILE-ACIDS",

author = "Mikko Neuvonen and P{\"a}ivi Hirvensalo and Aleksi Tornio and Brian Rago and Mark West and Sarah Lazzaro and Sumathy Mathialagan and Manthena Varma and Cerny, {Matthew A.} and Chester Costales and Ragu Ramanathan and Rodrigues, {A. David} and Mikko Niemi",

year = "2020",

month = oct,

day = "18",

doi = "10.1002/cpt.2053",

language = "English",

journal = "Clinical Pharmacology and Therapeutics",

issn = "0009-9236",

publisher = "Wiley",

}

Neuvonen, M, Hirvensalo, P , Tornio, A, Rago, B, West, M, Lazzaro, S, Mathialagan, S, Varma, M, Cerny, MA, Costales, C, Ramanathan, R, Rodrigues, AD & Niemi, M 2020, 'Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers', Clinical Pharmacology and Therapeutics. https://doi.org/10.1002/cpt.2053

Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers. / Neuvonen, Mikko; Hirvensalo, Päivi ; Tornio, Aleksi; Rago, Brian; West, Mark; Lazzaro, Sarah; Mathialagan, Sumathy; Varma, Manthena; Cerny, Matthew A.; Costales, Chester; Ramanathan, Ragu; Rodrigues, A. David; Niemi, Mikko.

I: Clinical Pharmacology and Therapeutics, 18.10.2020.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Identification of Glycochenodeoxycholate 3-O-glucuronide and Glycodeoxycholate 3-O-glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers

AU - Neuvonen, Mikko

AU - Hirvensalo, Päivi

AU - Tornio, Aleksi

AU - Rago, Brian

AU - West, Mark

AU - Lazzaro, Sarah

AU - Mathialagan, Sumathy

AU - Varma, Manthena

AU - Cerny, Matthew A.

AU - Costales, Chester

AU - Ramanathan, Ragu

AU - Rodrigues, A. David

AU - Niemi, Mikko

PY - 2020/10/18

Y1 - 2020/10/18

KW - ANION TRANSPORTING POLYPEPTIDE

KW - POLYMORPHISM MARKEDLY AFFECTS

KW - SLCO1B1 POLYMORPHISM

KW - ENDOGENOUS BIOMARKERS

KW - HAPLOTYPE RECONSTRUCTION

KW - PLASMA-CONCENTRATIONS

KW - CYNOMOLGUS MONKEYS

KW - DRUG-INTERACTION

KW - GENOME-WIDE

KW - BILE-ACIDS

U2 - 10.1002/cpt.2053

DO - 10.1002/cpt.2053

M3 - Article

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

SN - 0009-9236

ER -