In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models

Michael M. Luebtow; Sabrina Oerter; Sabina Quader; Elisabeth Jeanclos; Alevtina Cubukova; Marion Krafft; Malik Salman Haider; Clemens Schulte; Laura Meier; Maximilian Rist; Oltea Sampetrean; Hiroaki Kinoh; Antje Gohla; Kazunori Kataoka; Antje Appelt-Menzel; Robert Luxenhofer

doi:10.1021/acs.molpharmaceut.9b01117

In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models

Michael M. Luebtow, Sabrina Oerter, Sabina Quader, Elisabeth Jeanclos, Alevtina Cubukova, Marion Krafft, Malik Salman Haider, Clemens Schulte, Laura Meier, Maximilian Rist, Oltea Sampetrean, Hiroaki Kinoh, Antje Gohla, Kazunori Kataoka, Antje Appelt-Menzel, Robert Luxenhofer

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Molecular Pharmaceutics
Volym	17
Nummer	6
Sidor (från-till)	1835-1847
Antal sidor	13
ISSN	1543-8384
DOI	https://doi.org/10.1021/acs.molpharmaceut.9b01117
Status	Publicerad - 1 juni 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

317 Farmaci
116 Kemi

Åtkomst av dokument

10.1021/acs.molpharmaceut.9b01117

nanoATV Luebtow_R2Accepterat manuskript från författare, 1,1 MB

Citera det här

Luebtow, M. M., Oerter, S., Quader, S., Jeanclos, E., Cubukova, A., Krafft, M., Haider, M. S., Schulte, C., Meier, L., Rist, M., Sampetrean, O., Kinoh, H., Gohla, A., Kataoka, K., Appelt-Menzel, A., & Luxenhofer, R. (2020). In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models. Molecular Pharmaceutics, 17(6), 1835-1847. https://doi.org/10.1021/acs.molpharmaceut.9b01117

@article{82d772d5f15b45ea8d81c1076f7351d4,

title = "In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models",

keywords = "drug-loaded micelles, poly(2-oxazoline), poly(2-oxazine), nanomedicine, human induced-pluripotent stem cells, cancer stem cells, CANCER STEM-CELLS, BLOCK-COPOLYMERS, SPHEROID CULTURE, DRUG-DELIVERY, STATINS, RESISTANCE, INHIBITION, TRANSPORT, GLIOMA, VIVO, 317 Pharmacy, 116 Chemical sciences",

author = "Luebtow, {Michael M.} and Sabrina Oerter and Sabina Quader and Elisabeth Jeanclos and Alevtina Cubukova and Marion Krafft and Haider, {Malik Salman} and Clemens Schulte and Laura Meier and Maximilian Rist and Oltea Sampetrean and Hiroaki Kinoh and Antje Gohla and Kazunori Kataoka and Antje Appelt-Menzel and Robert Luxenhofer",

year = "2020",

month = jun,

day = "1",

doi = "10.1021/acs.molpharmaceut.9b01117",

language = "English",

volume = "17",

pages = "1835--1847",

journal = "Molecular Pharmaceutics",

issn = "1543-8384",

publisher = "American Chemical Society",

number = "6",

}

Luebtow, MM, Oerter, S, Quader, S, Jeanclos, E, Cubukova, A, Krafft, M, Haider, MS, Schulte, C, Meier, L, Rist, M, Sampetrean, O, Kinoh, H, Gohla, A, Kataoka, K, Appelt-Menzel, A & Luxenhofer, R 2020, 'In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models', Molecular Pharmaceutics, vol. 17, nr. 6, s. 1835-1847. https://doi.org/10.1021/acs.molpharmaceut.9b01117

TY - JOUR

T1 - In Vitro Blood-Brain Barrier Permeability and Cytotoxicity of an Atorvastatin-Loaded Nanoformulation Against Glioblastoma in 2D and 3D Models

AU - Luebtow, Michael M.

AU - Oerter, Sabrina

AU - Quader, Sabina

AU - Jeanclos, Elisabeth

AU - Cubukova, Alevtina

AU - Krafft, Marion

AU - Haider, Malik Salman

AU - Schulte, Clemens

AU - Meier, Laura

AU - Rist, Maximilian

AU - Sampetrean, Oltea

AU - Kinoh, Hiroaki

AU - Gohla, Antje

AU - Kataoka, Kazunori

AU - Appelt-Menzel, Antje

AU - Luxenhofer, Robert

PY - 2020/6/1

Y1 - 2020/6/1

KW - drug-loaded micelles

KW - poly(2-oxazoline)

KW - poly(2-oxazine)

KW - nanomedicine

KW - human induced-pluripotent stem cells

KW - cancer stem cells

KW - CANCER STEM-CELLS

KW - BLOCK-COPOLYMERS

KW - SPHEROID CULTURE

KW - DRUG-DELIVERY

KW - STATINS

KW - RESISTANCE

KW - INHIBITION

KW - TRANSPORT

KW - GLIOMA

KW - VIVO

KW - 317 Pharmacy

KW - 116 Chemical sciences

U2 - 10.1021/acs.molpharmaceut.9b01117

DO - 10.1021/acs.molpharmaceut.9b01117

M3 - Article

SN - 1543-8384

VL - 17

SP - 1835

EP - 1847

JO - Molecular Pharmaceutics

JF - Molecular Pharmaceutics

IS - 6

ER -