Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions

Kristian Semjonov, Maia Salm, Tiina Lipiäinen, Karin Kogermann, Andres Lust, Ivo Laidmäe, Osmo Antikainen, Clare J. Strachan, Henrik Ehlers, Jouko Yliruusi, Jyrki Heinämäki

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Originalspråkengelska
TidskriftInternational Journal of Pharmaceutics
Volym541
Utgåva1-2
Sidor (från-till)188-197
Antal sidor10
ISSN0378-5173
DOI
StatusPublicerad - 2018
MoE-publikationstypA1 Tidskriftsartikel-refererad

Vetenskapsgrenar

  • 317 Farmaci

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@article{2982b8591dab4eaf900ba3d89106a773,
title = "Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions",
keywords = "particle properties, bulk powder behavior, dissolution, solid dispersion, polymer, HOT-MELT EXTRUSION, WATER-SOLUBLE DRUG, AMORPHOUS INDOMETHACIN, DISSOLUTION RATE, PHYSICAL STABILITY, MIXTURES, SIZE, BIOAVAILABILITY, FLOWABILITY, FORMULATION, 317 Pharmacy",
author = "Kristian Semjonov and Maia Salm and Tiina Lipi{\"a}inen and Karin Kogermann and Andres Lust and Ivo Laidm{\"a}e and Osmo Antikainen and Strachan, {Clare J.} and Henrik Ehlers and Jouko Yliruusi and Jyrki Hein{\"a}m{\"a}ki",
year = "2018",
doi = "10.1016/j.ijpharm.2018.02.039",
language = "English",
volume = "541",
pages = "188--197",
journal = "International Journal of Pharmaceutics",
issn = "0378-5173",
publisher = "Elsevier Scientific Publ. Co",
number = "1-2",

}

Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions. / Semjonov, Kristian; Salm, Maia; Lipiäinen, Tiina; Kogermann, Karin; Lust, Andres; Laidmäe, Ivo; Antikainen, Osmo; Strachan, Clare J.; Ehlers, Henrik; Yliruusi, Jouko; Heinämäki, Jyrki.

I: International Journal of Pharmaceutics, Vol. 541, Nr. 1-2, 2018, s. 188-197.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

TY - JOUR

T1 - Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions

AU - Semjonov, Kristian

AU - Salm, Maia

AU - Lipiäinen, Tiina

AU - Kogermann, Karin

AU - Lust, Andres

AU - Laidmäe, Ivo

AU - Antikainen, Osmo

AU - Strachan, Clare J.

AU - Ehlers, Henrik

AU - Yliruusi, Jouko

AU - Heinämäki, Jyrki

PY - 2018

Y1 - 2018

KW - particle properties

KW - bulk powder behavior

KW - dissolution

KW - solid dispersion

KW - polymer

KW - HOT-MELT EXTRUSION

KW - WATER-SOLUBLE DRUG

KW - AMORPHOUS INDOMETHACIN

KW - DISSOLUTION RATE

KW - PHYSICAL STABILITY

KW - MIXTURES

KW - SIZE

KW - BIOAVAILABILITY

KW - FLOWABILITY

KW - FORMULATION

KW - 317 Pharmacy

U2 - 10.1016/j.ijpharm.2018.02.039

DO - 10.1016/j.ijpharm.2018.02.039

M3 - Article

VL - 541

SP - 188

EP - 197

JO - International Journal of Pharmaceutics

JF - International Journal of Pharmaceutics

SN - 0378-5173

IS - 1-2

ER -