Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects

Jarkko Johansson, Jussi Hirvonen, Zsofia Lovro, Laura Ekblad, Valtteri Kaasinen, Olli Rajasilta, Semi Helin, Jouni Tuisku, Saija Siren, Mirka Pennanen, Arvind Agrawal, Roger Crystal, Petri J. Vainio, Hannu Alho, Mika Scheinin

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Originalspråkengelska
TidskriftNeuropsychopharmacology
Volym44
Utgåva9
Sidor (från-till)1667-1673
Antal sidor7
ISSN0893-133X
DOI
StatusPublicerad - aug 2019
MoE-publikationstypA1 Tidskriftsartikel-refererad

Vetenskapsgrenar

  • 3112 Neurovetenskaper
  • 3124 Neurologi och psykiatri
  • 317 Farmaci

Citera det här

Johansson, J., Hirvonen, J., Lovro, Z., Ekblad, L., Kaasinen, V., Rajasilta, O., ... Scheinin, M. (2019). Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects. Neuropsychopharmacology, 44(9), 1667-1673. https://doi.org/10.1038/s41386-019-0368-x
Johansson, Jarkko ; Hirvonen, Jussi ; Lovro, Zsofia ; Ekblad, Laura ; Kaasinen, Valtteri ; Rajasilta, Olli ; Helin, Semi ; Tuisku, Jouni ; Siren, Saija ; Pennanen, Mirka ; Agrawal, Arvind ; Crystal, Roger ; Vainio, Petri J. ; Alho, Hannu ; Scheinin, Mika. / Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects. I: Neuropsychopharmacology. 2019 ; Vol. 44, Nr. 9. s. 1667-1673.
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title = "Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects",
keywords = "POSITRON-EMISSION-TOMOGRAPHY, PLACEBO-CONTROLLED TRIAL, DOUBLE-BLIND, IN-VIVO, EARLY ABSTINENCE, TEST-RETEST, NALTREXONE, BINDING, PET, OCCUPANCY, 3112 Neurosciences, 3124 Neurology and psychiatry, 317 Pharmacy",
author = "Jarkko Johansson and Jussi Hirvonen and Zsofia Lovro and Laura Ekblad and Valtteri Kaasinen and Olli Rajasilta and Semi Helin and Jouni Tuisku and Saija Siren and Mirka Pennanen and Arvind Agrawal and Roger Crystal and Vainio, {Petri J.} and Hannu Alho and Mika Scheinin",
year = "2019",
month = "8",
doi = "10.1038/s41386-019-0368-x",
language = "English",
volume = "44",
pages = "1667--1673",
journal = "Neuropsychopharmacology",
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Johansson, J, Hirvonen, J, Lovro, Z, Ekblad, L, Kaasinen, V, Rajasilta, O, Helin, S, Tuisku, J, Siren, S, Pennanen, M, Agrawal, A, Crystal, R, Vainio, PJ, Alho, H & Scheinin, M 2019, 'Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects', Neuropsychopharmacology, vol. 44, nr. 9, s. 1667-1673. https://doi.org/10.1038/s41386-019-0368-x

Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects. / Johansson, Jarkko; Hirvonen, Jussi; Lovro, Zsofia; Ekblad, Laura; Kaasinen, Valtteri; Rajasilta, Olli; Helin, Semi; Tuisku, Jouni; Siren, Saija; Pennanen, Mirka; Agrawal, Arvind; Crystal, Roger; Vainio, Petri J.; Alho, Hannu; Scheinin, Mika.

I: Neuropsychopharmacology, Vol. 44, Nr. 9, 08.2019, s. 1667-1673.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

TY - JOUR

T1 - Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects

AU - Johansson, Jarkko

AU - Hirvonen, Jussi

AU - Lovro, Zsofia

AU - Ekblad, Laura

AU - Kaasinen, Valtteri

AU - Rajasilta, Olli

AU - Helin, Semi

AU - Tuisku, Jouni

AU - Siren, Saija

AU - Pennanen, Mirka

AU - Agrawal, Arvind

AU - Crystal, Roger

AU - Vainio, Petri J.

AU - Alho, Hannu

AU - Scheinin, Mika

PY - 2019/8

Y1 - 2019/8

KW - POSITRON-EMISSION-TOMOGRAPHY

KW - PLACEBO-CONTROLLED TRIAL

KW - DOUBLE-BLIND

KW - IN-VIVO

KW - EARLY ABSTINENCE

KW - TEST-RETEST

KW - NALTREXONE

KW - BINDING

KW - PET

KW - OCCUPANCY

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

KW - 317 Pharmacy

U2 - 10.1038/s41386-019-0368-x

DO - 10.1038/s41386-019-0368-x

M3 - Article

VL - 44

SP - 1667

EP - 1673

JO - Neuropsychopharmacology

JF - Neuropsychopharmacology

SN - 0893-133X

IS - 9

ER -

Johansson J, Hirvonen J, Lovro Z, Ekblad L, Kaasinen V, Rajasilta O et al. Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects. Neuropsychopharmacology. 2019 aug;44(9):1667-1673. https://doi.org/10.1038/s41386-019-0368-x