TY - JOUR
T1 - Long-term results of late open conversions with partial or total removal of noninfected stent grafts after failed endovascular aneurysm repair
AU - CONFER Investigators
AU - Kaartama, Tuukka
AU - Esposito, Davide
AU - Pascucci, Maria Giulia
AU - Zacá, Sergio
AU - Angiletta, Domenico
AU - Civilini, Efrem
AU - Venermo, Maarit
AU - Pratesi, Giovanni
AU - Aho, Pekka
N1 - Publisher Copyright:
© 2025 The Author(s)
PY - 2025
Y1 - 2025
N2 - Objective: Open surgical conversion after failed EVAR has become more common. Our aim was to compare the short- and long-term results of late open conversions for noninfectious indications with partial or total stent graft removal. Methods: Our study is a retrospective, multicenter observational study of late open conversions performed in five hospitals between January 1997 and June 2024. Patients who underwent a partial or total removal of a stent graft more than 30 days after EVAR for noninfectious indications were included in the analysis and divided into two groups: partial conversion (PC) and total conversion (TC). The primary outcomes were 30-day mortality, 5-year survival, and freedom from late complications. The secondary outcomes were perioperative cardiovascular complications, length of hospital stay, and 5-year freedom from reinterventions and from aneurysm-related death. Results: The analysis included 97 patients: 57 (58.8%) in the PC group and 40 (41.2%) in the TC group. The 30-day mortality in the PC group was lower compared with the TC group (14.3% vs 24.3%; odds ratio, 0.52; P = .220), although the difference did not reach statistical significance. The estimated 5-year overall survival was similar in the PC and TC groups (58.8% vs 59.8%; P = .726). The patients in the PC group had no infections or thrombosis and a similar freedom from late complications compared with the TC group (81.2% vs 84.0%; P = .788). A subgroup analysis comparing the preoperative CTA scans and intraoperative observations revealed an occult endoleak in 22 patients (22.7%), and in the 12 patients (12.4%) who underwent surgery for a suspected endoleak, none were identified during the procedure. Conclusions: PC seems to be noninferior to TC and possibly even safer, with a trend toward lower mortality in the short term. No differences in mortality or complications were found between the groups during long-term follow-up.
AB - Objective: Open surgical conversion after failed EVAR has become more common. Our aim was to compare the short- and long-term results of late open conversions for noninfectious indications with partial or total stent graft removal. Methods: Our study is a retrospective, multicenter observational study of late open conversions performed in five hospitals between January 1997 and June 2024. Patients who underwent a partial or total removal of a stent graft more than 30 days after EVAR for noninfectious indications were included in the analysis and divided into two groups: partial conversion (PC) and total conversion (TC). The primary outcomes were 30-day mortality, 5-year survival, and freedom from late complications. The secondary outcomes were perioperative cardiovascular complications, length of hospital stay, and 5-year freedom from reinterventions and from aneurysm-related death. Results: The analysis included 97 patients: 57 (58.8%) in the PC group and 40 (41.2%) in the TC group. The 30-day mortality in the PC group was lower compared with the TC group (14.3% vs 24.3%; odds ratio, 0.52; P = .220), although the difference did not reach statistical significance. The estimated 5-year overall survival was similar in the PC and TC groups (58.8% vs 59.8%; P = .726). The patients in the PC group had no infections or thrombosis and a similar freedom from late complications compared with the TC group (81.2% vs 84.0%; P = .788). A subgroup analysis comparing the preoperative CTA scans and intraoperative observations revealed an occult endoleak in 22 patients (22.7%), and in the 12 patients (12.4%) who underwent surgery for a suspected endoleak, none were identified during the procedure. Conclusions: PC seems to be noninferior to TC and possibly even safer, with a trend toward lower mortality in the short term. No differences in mortality or complications were found between the groups during long-term follow-up.
KW - Abdominal aortic aneurysm
KW - Late open conversion
KW - Open surgical repair
KW - Partial removal
KW - Total removal
U2 - 10.1016/j.jvs.2025.02.023
DO - 10.1016/j.jvs.2025.02.023
M3 - Article
C2 - 40023263
AN - SCOPUS:105001480659
SN - 0741-5214
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
ER -