Maintenance pharmacotherapy for recurrent major depressive disorder: 5-year follow-up study

Irina Holma, Klaus Mikael Holma, Tarja Melartin, Erkki Isometsä

    Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

    Sammanfattning

    Practice guidelines endorse maintenance antidepressant treatment for recurrent major depressive disorder. In the Vantaa Depression Study, we followed 218 psychiatric patients with major depressive disorder for up to 5 years with a life-chart. Of these patients, 86 (39.4%) had more than three lifetime episodes and an indication for maintenance pharmacotherapy. However, of these, only 57% received treatment and only for 16% of the time indicated. Good adherence to pharmacotherapy in the acute phase independently predicted maintenance treatment. The tertiary preventive impact of maintenance treatment may remain limited, as many patients with major depressive disorder either do not receive it, or receive it for too short a period.
    Originalspråkengelska
    TidskriftBritish Journal of Psychiatry
    Volym193
    Utgåva2
    Sidor (från-till)163-164
    Antal sidor2
    ISSN0007-1250
    DOI
    StatusPublicerad - 2008
    MoE-publikationstypA1 Tidskriftsartikel-refererad

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