MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice

Yeawon Kim; Chuang Li; Chenjian Gu; Yili Fang; Eric Tycksen; Anuradhika Puri; Terri A. Pietka; Jothilingam Sivapackiam; Kendrah Kidd; Sun-Ji Park; Bryce G. Johnson; Stanislav Kmoch; Jeremy S. Duffield; Anthony J. Bleyer; Meredith E. Jackrel; Fumihiko Urano; Vijay Sharma; Maria Lindahl; Ying Maggie Chen

doi:10.1038/s41467-023-42154-0

MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice

Yeawon Kim, Chuang Li, Chenjian Gu, Yili Fang, Eric Tycksen, Anuradhika Puri, Terri A. Pietka, Jothilingam Sivapackiam, Kendrah Kidd, Sun-Ji Park, Bryce G. Johnson, Stanislav Kmoch, Jeremy S. Duffield, Anthony J. Bleyer, Meredith E. Jackrel, Fumihiko Urano, Vijay Sharma, Maria Lindahl, Ying Maggie Chen

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	6493
Tidskrift	Nature Communications
Volym	14
Antal sidor	22
ISSN	2041-1723
DOI	https://doi.org/10.1038/s41467-023-42154-0
Status	Publicerad - 14 okt. 2023
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

1182 Biokemi, cell- och molekylärbiologi

Åtkomst av dokument

10.1038/s41467-023-42154-0Licens: CC BY

s41467-023-42154-0Slutlig publicerad version, 6,77 MBLicens: CC BY

Citera det här

Kim, Y., Li, C., Gu, C., Fang, Y., Tycksen, E., Puri, A., Pietka, T. A., Sivapackiam, J., Kidd, K., Park, S.-J., Johnson, B. G., Kmoch, S., Duffield, J. S., Bleyer, A. J., Jackrel, M. E., Urano, F., Sharma, V., Lindahl, M., & Chen, Y. M. (2023). MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice. Nature Communications, 14, Artikel 6493. https://doi.org/10.1038/s41467-023-42154-0

@article{7a73df37fbe34d81b18dbe7c7abbc9ca,

title = "MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice",

keywords = "Endoplasmic-reticulum stress, Neurotrophic factor, Damage, Biogenesis, Protects, Mutation, 1182 Biochemistry, cell and molecular biology",

author = "Yeawon Kim and Chuang Li and Chenjian Gu and Yili Fang and Eric Tycksen and Anuradhika Puri and Pietka, {Terri A.} and Jothilingam Sivapackiam and Kendrah Kidd and Sun-Ji Park and Johnson, {Bryce G.} and Stanislav Kmoch and Duffield, {Jeremy S.} and Bleyer, {Anthony J.} and Jackrel, {Meredith E.} and Fumihiko Urano and Vijay Sharma and Maria Lindahl and Chen, {Ying Maggie}",

year = "2023",

month = oct,

day = "14",

doi = "10.1038/s41467-023-42154-0",

language = "English",

volume = "14",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

}

Kim, Y, Li, C, Gu, C, Fang, Y, Tycksen, E, Puri, A, Pietka, TA, Sivapackiam, J, Kidd, K, Park, S-J, Johnson, BG, Kmoch, S, Duffield, JS, Bleyer, AJ, Jackrel, ME, Urano, F, Sharma, V, Lindahl, M & Chen, YM 2023, 'MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice', Nature Communications, vol. 14, 6493. https://doi.org/10.1038/s41467-023-42154-0

TY - JOUR

T1 - MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice

AU - Kim, Yeawon

AU - Li, Chuang

AU - Gu, Chenjian

AU - Fang, Yili

AU - Tycksen, Eric

AU - Puri, Anuradhika

AU - Pietka, Terri A.

AU - Sivapackiam, Jothilingam

AU - Kidd, Kendrah

AU - Park, Sun-Ji

AU - Johnson, Bryce G.

AU - Kmoch, Stanislav

AU - Duffield, Jeremy S.

AU - Bleyer, Anthony J.

AU - Jackrel, Meredith E.

AU - Urano, Fumihiko

AU - Sharma, Vijay

AU - Lindahl, Maria

AU - Chen, Ying Maggie

PY - 2023/10/14

Y1 - 2023/10/14

KW - Endoplasmic-reticulum stress

KW - Neurotrophic factor

KW - Damage

KW - Biogenesis

KW - Protects

KW - Mutation

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1038/s41467-023-42154-0

DO - 10.1038/s41467-023-42154-0

M3 - Article

C2 - 37838725

SN - 2041-1723

VL - 14

JO - Nature Communications

JF - Nature Communications

M1 - 6493

ER -