Methods and uses related to ADAMTS3

Kari Alitalo; Michael Jeltsch; Sawan Kumar Jha; Denis Tvorogov

Methods and uses related to ADAMTS3

Kari Alitalo, Michael Jeltsch, Sawan Kumar Jha, Denis Tvorogov

Forskningsprogramenheten

Forskningsoutput: Patent

Sammanfattning

The present invention relates to the utilization of ADAMTS3 metalloprotease. More specifically, the present invention relates to a method of producing fully processed mature VEGF-C polypeptide by a cell and a method of cleaving VEGF-C polypeptides. Furthermore, the present invention relates to different uses of ADAMTS3, ADAMTS3 inhibitors or compositions comprising ADAMTS3 or ADAMTS3 inhibitors, and a method of treating a lymphatic disorder. In addition, the invention relates to a method of producing VEGF-Cbinding molecules.

Originalspråk	engelska
Utgivningsår	30 jul 2015
Status	Publicerad - 30 jul 2015
MoE-publikationstyp	H1 Beviljat patent

Vetenskapsgrenar

3111 Biomedicinska vetenskaper

Åtkomst av dokument

https://patentscope.wipo.int/search/en/WO2015110707

Andra filer och länkar

https://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2015110707&KC=&FT=E&locale=en_EP#

Citera det här

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N2 - The present invention relates to the utilization of ADAMTS3 metalloprotease. More specifically, the present invention relates to a method of producing fully processed mature VEGF-C polypeptide by a cell and a method of cleaving VEGF-C polypeptides. Furthermore, the present invention relates to different uses of ADAMTS3, ADAMTS3 inhibitors or compositions comprising ADAMTS3 or ADAMTS3 inhibitors, and a method of treating a lymphatic disorder. In addition, the invention relates to a method of producing VEGF-Cbinding molecules.

AB - The present invention relates to the utilization of ADAMTS3 metalloprotease. More specifically, the present invention relates to a method of producing fully processed mature VEGF-C polypeptide by a cell and a method of cleaving VEGF-C polypeptides. Furthermore, the present invention relates to different uses of ADAMTS3, ADAMTS3 inhibitors or compositions comprising ADAMTS3 or ADAMTS3 inhibitors, and a method of treating a lymphatic disorder. In addition, the invention relates to a method of producing VEGF-Cbinding molecules.

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