Sammanfattning
The present invention relates to the utilization of ADAMTS3 metalloprotease. More specifically, the present invention relates to a method of producing fully processed mature VEGF-C polypeptide by a cell and a method of cleaving VEGF-C polypeptides. Furthermore, the present invention relates to different uses of ADAMTS3, ADAMTS3 inhibitors or compositions comprising ADAMTS3 or ADAMTS3 inhibitors, and a method of treating a lymphatic disorder. In addition, the invention relates to a method of producing VEGF-Cbinding molecules.
Originalspråk | engelska |
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Utgivningsår | 30 jul 2015 |
Status | Publicerad - 30 jul 2015 |
MoE-publikationstyp | H1 Beviljat patent |
Vetenskapsgrenar
- 3111 Biomedicinska vetenskaper