Modified VEGF-A with improved angiogenic properties

Kari Kustaa Alitalo, Tuomas Leo Herman Tammela, Salla Elina Keskitalo, Katri Marianna Pajusola, Markku Michael Jeltsch, Seppo Ylä-Herttuala, Terhi Hannele Kärpänen, Ulf Eriksson, Marko Juha Tapani Uutela

Forskningsoutput: Patent

Sammanfattning

The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.
Originalspråkengelska
Utgivningsår27 sep 2011
StatusPublicerad - 27 sep 2011
MoE-publikationstypH1 Beviljat patent

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