The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.
|Utgivningsår||27 sep 2011|
|Status||Publicerad - 27 sep 2011|
|MoE-publikationstyp||H1 Beviljat patent|