NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62

Nikolas Furthmann; Verian Bader; Lena Angersbach; Alina Blusch; Simran Goel; Ana Sanchez-Vicente; Laura J. Krause; Sarah A. Chaban; Prerna Grover; Victoria A. Trinkaus; Eva M. van Well; Maximilian Jaugstetter; Kristina Tschulik; Rune Busk Damgaard; Carsten Saft; Gisa Ellrichmann; Ralf Gold; Arend Koch; Benjamin Englert; Ana Westenberger; Christine Klein; Lisa Jungbluth; Carsten Sachse; Christian Behrends; Markus Glatzel; F. Ulrich Hartl; Ken Nakamura; Chadwick W. Christine; Eric J. Huang; Jorg Tatzelt; Konstanze F. Winklhofer

doi:10.1038/s41467-023-44033-0

NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62

Nikolas Furthmann
, Verian Bader
, Lena Angersbach
, Alina Blusch
, Simran Goel
, Ana Sanchez-Vicente
, Laura J. Krause
, Sarah A. Chaban
, Prerna Grover
, Victoria A. Trinkaus
, Eva M. van Well
, Maximilian Jaugstetter
, Kristina Tschulik
, Rune Busk Damgaard
, Carsten Saft
, Gisa Ellrichmann
, Ralf Gold
, Arend Koch
, Benjamin Englert
, Ana Westenberger

Christine Klein, Lisa Jungbluth, Carsten Sachse, Christian Behrends, Markus Glatzel, F. Ulrich Hartl, Ken Nakamura, Chadwick W. Christine, Eric J. Huang, Jorg Tatzelt, Konstanze F. Winklhofer

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	8368
Tidskrift	Nature Communications
Volym	14
Nummer	1
Antal sidor	24
ISSN	2041-1723
DOI	https://doi.org/10.1038/s41467-023-44033-0
Status	Publicerad - 19 dec. 2023
Externt publicerad	Ja
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Åtkomst av dokument

10.1038/s41467-023-44033-0

s41467-023-44033-0Slutlig publicerad version, 22,2 MBLicens: CC BY

Citera det här

Furthmann, N., Bader, V., Angersbach, L., Blusch, A., Goel, S., Sanchez-Vicente, A., Krause, L. J., Chaban, S. A., Grover, P., Trinkaus, V. A., van Well, E. M., Jaugstetter, M., Tschulik, K., Damgaard, R. B., Saft, C., Ellrichmann, G., Gold, R., Koch, A., Englert, B., ... Winklhofer, K. F. (2023). NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62. Nature Communications, 14(1), Artikel 8368. https://doi.org/10.1038/s41467-023-44033-0

@article{020a4fe5aaed41a282983800ab82bcc1,

title = "NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62",

keywords = "Nf-kappa-b, Linear ubiquitin chains, Nerve growth-factor, Selective autophagy, Mediates neuroprotection, Activation, Binding, P62/sqstm1, Mechanism, Complex",

author = "Nikolas Furthmann and Verian Bader and Lena Angersbach and Alina Blusch and Simran Goel and Ana Sanchez-Vicente and Krause, \{Laura J.\} and Chaban, \{Sarah A.\} and Prerna Grover and Trinkaus, \{Victoria A.\} and \{van Well\}, \{Eva M.\} and Maximilian Jaugstetter and Kristina Tschulik and Damgaard, \{Rune Busk\} and Carsten Saft and Gisa Ellrichmann and Ralf Gold and Arend Koch and Benjamin Englert and Ana Westenberger and Christine Klein and Lisa Jungbluth and Carsten Sachse and Christian Behrends and Markus Glatzel and Hartl, \{F. Ulrich\} and Ken Nakamura and Christine, \{Chadwick W.\} and Huang, \{Eric J.\} and Jorg Tatzelt and Winklhofer, \{Konstanze F.\}",

year = "2023",

month = dec,

day = "19",

doi = "10.1038/s41467-023-44033-0",

language = "English",

volume = "14",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

number = "1",

}

Furthmann, N, Bader, V, Angersbach, L, Blusch, A, Goel, S, Sanchez-Vicente, A, Krause, LJ, Chaban, SA, Grover, P, Trinkaus, VA, van Well, EM, Jaugstetter, M, Tschulik, K, Damgaard, RB, Saft, C, Ellrichmann, G, Gold, R, Koch, A, Englert, B, Westenberger, A, Klein, C, Jungbluth, L, Sachse, C, Behrends, C, Glatzel, M, Hartl, FU, Nakamura, K, Christine, CW, Huang, EJ, Tatzelt, J & Winklhofer, KF 2023, 'NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62', Nature Communications, vol. 14, nr. 1, 8368. https://doi.org/10.1038/s41467-023-44033-0

TY - JOUR

T1 - NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62

AU - Furthmann, Nikolas

AU - Bader, Verian

AU - Angersbach, Lena

AU - Blusch, Alina

AU - Goel, Simran

AU - Sanchez-Vicente, Ana

AU - Krause, Laura J.

AU - Chaban, Sarah A.

AU - Grover, Prerna

AU - Trinkaus, Victoria A.

AU - van Well, Eva M.

AU - Jaugstetter, Maximilian

AU - Tschulik, Kristina

AU - Damgaard, Rune Busk

AU - Saft, Carsten

AU - Ellrichmann, Gisa

AU - Gold, Ralf

AU - Koch, Arend

AU - Englert, Benjamin

AU - Westenberger, Ana

AU - Klein, Christine

AU - Jungbluth, Lisa

AU - Sachse, Carsten

AU - Behrends, Christian

AU - Glatzel, Markus

AU - Hartl, F. Ulrich

AU - Nakamura, Ken

AU - Christine, Chadwick W.

AU - Huang, Eric J.

AU - Tatzelt, Jorg

AU - Winklhofer, Konstanze F.

PY - 2023/12/19

Y1 - 2023/12/19

KW - Nf-kappa-b

KW - Linear ubiquitin chains

KW - Nerve growth-factor

KW - Selective autophagy

KW - Mediates neuroprotection

KW - Activation

KW - Binding

KW - P62/sqstm1

KW - Mechanism

KW - Complex

U2 - 10.1038/s41467-023-44033-0

DO - 10.1038/s41467-023-44033-0

M3 - Article

C2 - 38114471

SN - 2041-1723

VL - 14

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 8368

ER -