Objectively measured physical activity profile and cognition in Finnish elderly twins

Paula Iso-Markku, Katja Waller, Eero Vuoksimaa, Henri Vähä-Ypyä, Noora Lindgren, Kauko Heikkilä, Harri Sievänen, Juha Rinne, Jaakko Kaprio, Urho M. Kujala

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review


Introduction We studied whether objectively measured physical activity (PA) and sedentary behavior (SB) are associated with cognition in Finnish elderly twins. Methods This cross-sectional study comprised twins born in Finland from 1940 to 1944 in the Older Finnish Twin Cohort (mean age, 72.9 years; 726 persons). From 2014 to 2016, cognition was assessed with a validated telephonic interview, whereas PA was measured with a waist-worn accelerometer. Results In between-family models, SB and light physical activity had significant linear associations with cognition after adjusting for age, sex, wearing time, education level, body mass index, and living condition (SB: β-estimate, −0.21 [95% confidence intervals, −0.42 to −0.003]; light physical activity: β-estimate, 0.30 [95% confidence intervals, 0.02–0.58]). In within-family models, there were no significant linear associations between objectively measured PA and cognition. Discussion Objectively measured light physical activity and SB are associated with cognition in Finnish twins in their seventies, but the associations were attributable to genetic and environmental selection.
TidskriftAlzheimer's & Dementia: Translational Research & Clinical Interventions
Sidor (från-till)263-271
Antal sidor9
StatusPublicerad - 14 jul 2018
MoE-publikationstypA1 Tidskriftsartikel-refererad


  • 3124 Neurologi och psykiatri
  • 315 Gymnastik- och idrottsvetenskap

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