Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants

Elmo Christian Saarentaus; Aki Samuli Havulinna; Nina Mars; Ari Ahola-Olli; Tuomo Tapio Johannes Kiiskinen; Juulia Partanen; Sanni Ruotsalainen; Mitja Kurki; Lea Martta Urpa; Lei Chen; Markus Perola; Veikko Salomaa; Juha Veijola; Minna Männikkö; Ira M. Hall; Olli Pietiläinen; Jaakko Kaprio; Samuli Ripatti; Mark Daly; Aarno Palotie

doi:10.1038/s41380-021-01026-z

Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants

Elmo Christian Saarentaus, Aki Samuli Havulinna, Nina Mars, Ari Ahola-Olli, Tuomo Tapio Johannes Kiiskinen, Juulia Partanen, Sanni Ruotsalainen, Mitja Kurki, Lea Martta Urpa, Lei Chen, Markus Perola, Veikko Salomaa, Juha Veijola, Minna Männikkö, Ira M. Hall, Olli Pietiläinen, Jaakko Kaprio, Samuli Ripatti, Mark Daly, Aarno Palotie

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Molecular Psychiatry
Volym	26
Nummer	9
Sidor (från-till)	4884-4895
Antal sidor	12
ISSN	1359-4184
DOI	https://doi.org/10.1038/s41380-021-01026-z
Status	Publicerad - sep. 2021
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3124 Neurologi och psykiatri
1182 Biokemi, cell- och molekylärbiologi

Åtkomst av dokument

10.1038/s41380-021-01026-zLicens: CC BY

s41380-021-01026-zSlutlig publicerad version, 1,03 MBLicens: CC BY

Citera det här

Saarentaus, E. C., Havulinna, A. S., Mars, N., Ahola-Olli, A., Kiiskinen, T. T. J., Partanen, J., Ruotsalainen, S., Kurki, M., Urpa, L. M., Chen, L., Perola, M., Salomaa, V., Veijola, J., Männikkö, M., Hall, I. M., Pietiläinen, O., Kaprio, J., Ripatti, S., Daly, M., & Palotie, A. (2021). Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants. Molecular Psychiatry, 26(9), 4884-4895. https://doi.org/10.1038/s41380-021-01026-z

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title = "Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants",

keywords = "SCHIZOPHRENIA, DISORDERS, ASSOCIATION, PHENOTYPE, MORTALITY, EDUCATION, 3124 Neurology and psychiatry, 1182 Biochemistry, cell and molecular biology",

author = "Saarentaus, {Elmo Christian} and Havulinna, {Aki Samuli} and Nina Mars and Ari Ahola-Olli and Kiiskinen, {Tuomo Tapio Johannes} and Juulia Partanen and Sanni Ruotsalainen and Mitja Kurki and Urpa, {Lea Martta} and Lei Chen and Markus Perola and Veikko Salomaa and Juha Veijola and Minna M{\"a}nnikk{\"o} and Hall, {Ira M.} and Olli Pietil{\"a}inen and Jaakko Kaprio and Samuli Ripatti and Mark Daly and Aarno Palotie",

year = "2021",

month = sep,

doi = "10.1038/s41380-021-01026-z",

language = "English",

volume = "26",

pages = "4884--4895",

journal = "Molecular Psychiatry",

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Saarentaus, EC , Havulinna, AS , Mars, N , Ahola-Olli, A , Kiiskinen, TTJ , Partanen, J , Ruotsalainen, S, Kurki, M, Urpa, LM, Chen, L, Perola, M, Salomaa, V, Veijola, J, Männikkö, M, Hall, IM, Pietiläinen, O , Kaprio, J , Ripatti, S , Daly, M & Palotie, A 2021, 'Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants', Molecular Psychiatry, vol. 26, nr. 9, s. 4884-4895. https://doi.org/10.1038/s41380-021-01026-z

TY - JOUR

T1 - Polygenic burden has broader impact on health, cognition, and socioeconomic outcomes than most rare and high-risk copy number variants

AU - Saarentaus, Elmo Christian

AU - Havulinna, Aki Samuli

AU - Mars, Nina

AU - Ahola-Olli, Ari

AU - Kiiskinen, Tuomo Tapio Johannes

AU - Partanen, Juulia

AU - Ruotsalainen, Sanni

AU - Kurki, Mitja

AU - Urpa, Lea Martta

AU - Chen, Lei

AU - Perola, Markus

AU - Salomaa, Veikko

AU - Veijola, Juha

AU - Männikkö, Minna

AU - Hall, Ira M.

AU - Pietiläinen, Olli

AU - Kaprio, Jaakko

AU - Ripatti, Samuli

AU - Daly, Mark

AU - Palotie, Aarno

PY - 2021/9

Y1 - 2021/9

KW - SCHIZOPHRENIA

KW - DISORDERS

KW - ASSOCIATION

KW - PHENOTYPE

KW - MORTALITY

KW - EDUCATION

KW - 3124 Neurology and psychiatry

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1038/s41380-021-01026-z

DO - 10.1038/s41380-021-01026-z

M3 - Article

VL - 26

SP - 4884

EP - 4895

JO - Molecular Psychiatry

JF - Molecular Psychiatry

SN - 1359-4184

IS - 9

ER -