Post-Operative Pancreatic Fistula After Pancreatic Surgery

Kjetil Søreide, Ville J. Sallinen, Jenny L. Rystedt, Rowan W. Parks

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

Sammanfattning

One of the most dreaded complications of pancreatic surgery is the development of a post-operative pancreatic fistula (POPF). Appropriate understanding of the underlying pathophysiology, risk factors and perioperative mechanisms may allow for better management and use of preventive measures. Several risk scores have been developed but none are perfect in predicting POPF risk. Recognized factors include those related to the patient, the pathology and perioperative care. Interventions such as use of drains, stents and various drugs to mediate risk is still debated. Emerging data suggest that both the microbiome and inflammation in the post-operative phase may play important roles in the development of POPF. Available risk scores allow for stratification of risk and mitigation strategies can be tailored to reduce this. However, accurate estimation of risk remains a challenge and mechanisms are only partially understood.
Originalspråkengelska
Titel på värdpublikationTextbook of Pancreatic Cancer: Principles and Practice of Surgical Oncology
RedaktörerKjetil Søreide, Stefan Stättner
Antal sidor25
UtgivningsortCham
FörlagSpringer International Publishing
Utgivningsdatum2021
Utgåva1
Sidor1043-1067
ISBN (tryckt)978-3-030-53785-2
ISBN (elektroniskt)978-3-030-53786-9
DOI
StatusPublicerad - 2021
MoE-publikationstypA3 Del av bok eller annan forskningsbok

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  • 3122 Cancersjukdomar

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