Simultaneous p53 and p16 Immunostaining for Molecular Subclassification of Head and Neck Squamous Cell Carcinomas

Pihla Pakkanen, Antti Silvoniemi, Katri Aro, Leif Bäck, Heikki Irjala, Leena-Maija Aaltonen, Jaana Hagström, Caj Haglund, Jukka Laine, Heikki Minn, Jutta Huvila

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Sammanfattning

Purpose: Our aim was to assess the ability of simultaneous immunohistochemical staining (IHC) for p16 and p53 to accurately subclassify head and neck squamous cell carcinomas (HNSCC) as HPV-associated (HPV-A) versus HPV-independent (HPV-I) and compare p53 IHC staining patterns to TP53 mutation status, p16 IHC positivity and HPV status.

Originalspråkengelska
Artikelnummer73
Tidskrift Head and neck pathology
Volym18
Nummer1
Antal sidor10
ISSN1936-055X
DOI
StatusPublicerad - 2024
MoE-publikationstypA1 Tidskriftsartikel-refererad

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© The Author(s) 2024.

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  • 3125 Öron-, näs- och halssjukdomar, ögonsjukdomar

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