Single-cell characterization of anti-LAG-3 and anti- PD-1 combination treatment in patients with melanoma

Jani Huuhtanen; Henna Kasanen; Katriina Peltola; Tapio Lönnberg; Virpi Glumoff; Oscar Bruck; Olli Dufva; Karita Peltonen; Johanna Vikkula; Emmi Jokinen; Mette Ilander; Moon Hee Lee; Siru Mäkelä; Marta Nyakas; Bin Li; Micaela Hernberg; Petri Bono; Harri Lahdesmaki; Anna Kreutzman; Satu Mustjoki

doi:10.1172/JCI164809

Single-cell characterization of anti-LAG-3 and anti- PD-1 combination treatment in patients with melanoma

Jani Huuhtanen, Henna Kasanen, Katriina Peltola, Tapio Lönnberg, Virpi Glumoff, Oscar Bruck, Olli Dufva, Karita Peltonen, Johanna Vikkula, Emmi Jokinen, Mette Ilander, Moon Hee Lee, Siru Mäkelä, Marta Nyakas, Bin Li, Micaela Hernberg, Petri Bono, Harri Lahdesmaki, Anna Kreutzman, Satu Mustjoki

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	e164809
Tidskrift	Journal of Clinical Investigation
Volym	133
Nummer	6
Antal sidor	18
ISSN	0021-9738
DOI	https://doi.org/10.1172/JCI164809
Status	Publicerad - 15 mars 2023
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3122 Cancersjukdomar

Åtkomst av dokument

10.1172/JCI164809

JCI164809.v3Slutlig publicerad version, 2,89 MBLicens: CC BY

Citera det här

Huuhtanen, J., Kasanen, H., Peltola, K., Lönnberg, T., Glumoff, V., Bruck, O., Dufva, O., Peltonen, K., Vikkula, J., Jokinen, E., Ilander, M., Lee, M. H., Mäkelä, S., Nyakas, M., Li, B., Hernberg, M., Bono, P., Lahdesmaki, H., Kreutzman, A., & Mustjoki, S. (2023). Single-cell characterization of anti-LAG-3 and anti- PD-1 combination treatment in patients with melanoma. Journal of Clinical Investigation, 133(6), Artikel e164809. https://doi.org/10.1172/JCI164809

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title = "Single-cell characterization of anti-LAG-3 and anti- PD-1 combination treatment in patients with melanoma",

keywords = "Nk cells, Responses, Blockade, Lag-3, Cd223, Immunotherapy, Resistance, Evolution, 3122 Cancers",

author = "Jani Huuhtanen and Henna Kasanen and Katriina Peltola and Tapio L{\"o}nnberg and Virpi Glumoff and Oscar Bruck and Olli Dufva and Karita Peltonen and Johanna Vikkula and Emmi Jokinen and Mette Ilander and Lee, {Moon Hee} and Siru M{\"a}kel{\"a} and Marta Nyakas and Bin Li and Micaela Hernberg and Petri Bono and Harri Lahdesmaki and Anna Kreutzman and Satu Mustjoki",

year = "2023",

month = mar,

day = "15",

doi = "10.1172/JCI164809",

language = "English",

volume = "133",

journal = "Journal of Clinical Investigation",

issn = "0021-9738",

publisher = "AMERICAN SOCIETY FOR CLINICAL INVESTIGATION",

number = "6",

}

Huuhtanen, J, Kasanen, H, Peltola, K, Lönnberg, T, Glumoff, V, Bruck, O, Dufva, O, Peltonen, K, Vikkula, J, Jokinen, E , Ilander, M, Lee, MH, Mäkelä, S, Nyakas, M, Li, B, Hernberg, M, Bono, P, Lahdesmaki, H, Kreutzman, A & Mustjoki, S 2023, 'Single-cell characterization of anti-LAG-3 and anti- PD-1 combination treatment in patients with melanoma', Journal of Clinical Investigation, vol. 133, nr. 6, e164809. https://doi.org/10.1172/JCI164809

TY - JOUR

T1 - Single-cell characterization of anti-LAG-3 and anti- PD-1 combination treatment in patients with melanoma

AU - Huuhtanen, Jani

AU - Kasanen, Henna

AU - Peltola, Katriina

AU - Lönnberg, Tapio

AU - Glumoff, Virpi

AU - Bruck, Oscar

AU - Dufva, Olli

AU - Peltonen, Karita

AU - Vikkula, Johanna

AU - Jokinen, Emmi

AU - Ilander, Mette

AU - Lee, Moon Hee

AU - Mäkelä, Siru

AU - Nyakas, Marta

AU - Li, Bin

AU - Hernberg, Micaela

AU - Bono, Petri

AU - Lahdesmaki, Harri

AU - Kreutzman, Anna

AU - Mustjoki, Satu

PY - 2023/3/15

Y1 - 2023/3/15

KW - Nk cells

KW - Responses

KW - Blockade

KW - Lag-3

KW - Cd223

KW - Immunotherapy

KW - Resistance

KW - Evolution

KW - 3122 Cancers

U2 - 10.1172/JCI164809

DO - 10.1172/JCI164809

M3 - Article

C2 - 36719749

SN - 0021-9738

VL - 133

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

IS - 6

M1 - e164809

ER -