Solid-phase synthesis of pyrazolopyridines from polymer-bound alkyne and azomethine imines

Kirsi Harju, Irene Kylänlahti, Timo Paananen, Mika Polamo, John Nielsen, Jari Yli-Kauhaluoma

Forskningsoutput: TidskriftsbidragArtikelPeer review

Sammanfattning

Study was made of the 1,3-dipolar cycloaddition of polymer-bound alkynes to azomethine imines generated in situ from N-aminopyridine iodides. Aromatization of the cycloadducts gives polymer-bound pyrazolo-pyridines that can be released from the resin as carboxylic acids with trifluoroacetic acid or as methyl esters with sodium methoxide.
Originalspråkengelska
TidskriftJournal of Combinatorial Chemistry
Volym8
Utgåva3
Sidor (från-till)344-349
Antal sidor6
ISSN1520-4766
DOI
StatusPublicerad - 2006
MoE-publikationstypA1 Tidskriftsartikel-refererad

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