Synaptic, transcriptional and chromatin genes disrupted in autism

Silvia De Rubeis; Xin He; Arthur P. Goldberg; Christopher S. Poultney; Kaitlin Samocha; A. Ercument Cicek; Yan Kou; Li Liu; Menachem Fromer; Susan Walker; Tarjinder Singh; Lambertus Klei; Jack Kosmicki; Shih-Chen Fu; Branko Aleksic; Monica Biscaldi; Patrick F. Bolton; Jessica M. Brownfeld; Jinlu Cai; Nicholas G. Campbell; Angel Carracedo; Maria H. Chahrour; Andreas G. Chiocchetti; Hilary Coon; Emily L. Crawford; Lucy Crooks; Sarah R. Curran; Geraldine Dawson; Eftichia Duketis; Bridget A. Fernandez; Louise Gallagher; Evan Geller; Stephen J. Guter; R. Sean Hill; Iuliana Ionita-Laza; Patricia Jimenez Gonzalez; Helena Kilpinen; Sabine M. Klauck; Alexander Kolevzon; Irene Lee; Jing Lei; Terho Lehtimaeki; Chiao-Feng Lin; Avi Ma'ayan; Christian R. Marshall; Alison L. McInnes; Benjamin Neale; Michael J. Owen; Aarno Palotie; Mark J. Daly; DDD Study; Homozygosity Mapping Collaborative; UK10K Consortium; Autism Sequencing Consortium

doi:10.1038/nature13772

Synaptic, transcriptional and chromatin genes disrupted in autism

Silvia De Rubeis, Xin He, Arthur P. Goldberg, Christopher S. Poultney, Kaitlin Samocha, A. Ercument Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker, Tarjinder Singh, Lambertus Klei, Jack Kosmicki, Shih-Chen Fu, Branko Aleksic, Monica Biscaldi, Patrick F. Bolton, Jessica M. Brownfeld, Jinlu Cai, Nicholas G. CampbellAngel Carracedo, Maria H. Chahrour, Andreas G. Chiocchetti, Hilary Coon, Emily L. Crawford, Lucy Crooks, Sarah R. Curran, Geraldine Dawson, Eftichia Duketis, Bridget A. Fernandez, Louise Gallagher, Evan Geller, Stephen J. Guter, R. Sean Hill, Iuliana Ionita-Laza, Patricia Jimenez Gonzalez, Helena Kilpinen, Sabine M. Klauck, Alexander Kolevzon, Irene Lee, Jing Lei, Terho Lehtimaeki, Chiao-Feng Lin, Avi Ma'ayan, Christian R. Marshall, Alison L. McInnes, Benjamin Neale, Michael J. Owen, Aarno Palotie, Mark J. Daly, DDD Study, Homozygosity Mapping Collaborative, UK10K Consortium, Autism Sequencing Consortium

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Nature
Volym	515
Nummer	7526
Sidor (från-till)	209-U119
Antal sidor	16
ISSN	0028-0836
DOI	https://doi.org/10.1038/nature13772
Status	Publicerad - 13 nov. 2014
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper

Åtkomst av dokument

10.1038/nature13772

Citera det här

De Rubeis, S., He, X., Goldberg, A. P., Poultney, C. S., Samocha, K., Cicek, A. E., Kou, Y., Liu, L., Fromer, M., Walker, S., Singh, T., Klei, L., Kosmicki, J., Fu, S-C., Aleksic, B., Biscaldi, M., Bolton, P. F., Brownfeld, J. M., Cai, J., ... Autism Sequencing Consortium (2014). Synaptic, transcriptional and chromatin genes disrupted in autism. Nature, 515(7526), 209-U119. https://doi.org/10.1038/nature13772

@article{5cd4bfc1ee3d4074892073e59677ec0e,

title = "Synaptic, transcriptional and chromatin genes disrupted in autism",

keywords = "DE-NOVO MUTATIONS, COPY-NUMBER VARIATION, SPECTRUM DISORDERS, NEURODEVELOPMENTAL DISORDERS, FRAMEWORK, NETWORK, RISK, SCHIZOPHRENIA, EXPRESSION, DISCOVERY, 3111 Biomedicine",

author = "{De Rubeis}, Silvia and Xin He and Goldberg, {Arthur P.} and Poultney, {Christopher S.} and Kaitlin Samocha and Cicek, {A. Ercument} and Yan Kou and Li Liu and Menachem Fromer and Susan Walker and Tarjinder Singh and Lambertus Klei and Jack Kosmicki and Shih-Chen Fu and Branko Aleksic and Monica Biscaldi and Bolton, {Patrick F.} and Brownfeld, {Jessica M.} and Jinlu Cai and Campbell, {Nicholas G.} and Angel Carracedo and Chahrour, {Maria H.} and Chiocchetti, {Andreas G.} and Hilary Coon and Crawford, {Emily L.} and Lucy Crooks and Curran, {Sarah R.} and Geraldine Dawson and Eftichia Duketis and Fernandez, {Bridget A.} and Louise Gallagher and Evan Geller and Guter, {Stephen J.} and Hill, {R. Sean} and Iuliana Ionita-Laza and Gonzalez, {Patricia Jimenez} and Helena Kilpinen and Klauck, {Sabine M.} and Alexander Kolevzon and Irene Lee and Jing Lei and Terho Lehtimaeki and Chiao-Feng Lin and Avi Ma'ayan and Marshall, {Christian R.} and McInnes, {Alison L.} and Benjamin Neale and Owen, {Michael J.} and Aarno Palotie and Daly, {Mark J.} and {DDD Study} and {Homozygosity Mapping Collaborative} and {UK10K Consortium} and {Autism Sequencing Consortium}",

year = "2014",

month = nov,

day = "13",

doi = "10.1038/nature13772",

language = "English",

volume = "515",

pages = "209--U119",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Publishing Group",

number = "7526",

}

De Rubeis, S, He, X, Goldberg, AP, Poultney, CS, Samocha, K, Cicek, AE, Kou, Y, Liu, L, Fromer, M, Walker, S, Singh, T, Klei, L, Kosmicki, J, Fu, S-C, Aleksic, B, Biscaldi, M, Bolton, PF, Brownfeld, JM, Cai, J, Campbell, NG, Carracedo, A, Chahrour, MH, Chiocchetti, AG, Coon, H, Crawford, EL, Crooks, L, Curran, SR, Dawson, G, Duketis, E, Fernandez, BA, Gallagher, L, Geller, E, Guter, SJ, Hill, RS, Ionita-Laza, I, Gonzalez, PJ, Kilpinen, H, Klauck, SM, Kolevzon, A, Lee, I, Lei, J, Lehtimaeki, T, Lin, C-F, Ma'ayan, A, Marshall, CR, McInnes, AL, Neale, B, Owen, MJ, Palotie, A , Daly, MJ, DDD Study, Homozygosity Mapping Collaborative, UK10K Consortium & Autism Sequencing Consortium 2014, 'Synaptic, transcriptional and chromatin genes disrupted in autism', Nature, vol. 515, nr. 7526, s. 209-U119. https://doi.org/10.1038/nature13772

TY - JOUR

T1 - Synaptic, transcriptional and chromatin genes disrupted in autism

AU - De Rubeis, Silvia

AU - He, Xin

AU - Goldberg, Arthur P.

AU - Poultney, Christopher S.

AU - Samocha, Kaitlin

AU - Cicek, A. Ercument

AU - Kou, Yan

AU - Liu, Li

AU - Fromer, Menachem

AU - Walker, Susan

AU - Singh, Tarjinder

AU - Klei, Lambertus

AU - Kosmicki, Jack

AU - Fu, Shih-Chen

AU - Aleksic, Branko

AU - Biscaldi, Monica

AU - Bolton, Patrick F.

AU - Brownfeld, Jessica M.

AU - Cai, Jinlu

AU - Campbell, Nicholas G.

AU - Carracedo, Angel

AU - Chahrour, Maria H.

AU - Chiocchetti, Andreas G.

AU - Coon, Hilary

AU - Crawford, Emily L.

AU - Crooks, Lucy

AU - Curran, Sarah R.

AU - Dawson, Geraldine

AU - Duketis, Eftichia

AU - Fernandez, Bridget A.

AU - Gallagher, Louise

AU - Geller, Evan

AU - Guter, Stephen J.

AU - Hill, R. Sean

AU - Ionita-Laza, Iuliana

AU - Gonzalez, Patricia Jimenez

AU - Kilpinen, Helena

AU - Klauck, Sabine M.

AU - Kolevzon, Alexander

AU - Lee, Irene

AU - Lei, Jing

AU - Lehtimaeki, Terho

AU - Lin, Chiao-Feng

AU - Ma'ayan, Avi

AU - Marshall, Christian R.

AU - McInnes, Alison L.

AU - Neale, Benjamin

AU - Owen, Michael J.

AU - Palotie, Aarno

AU - Daly, Mark J.

AU - DDD Study

AU - Homozygosity Mapping Collaborative

AU - UK10K Consortium

AU - Autism Sequencing Consortium

PY - 2014/11/13

Y1 - 2014/11/13

KW - DE-NOVO MUTATIONS

KW - COPY-NUMBER VARIATION

KW - SPECTRUM DISORDERS

KW - NEURODEVELOPMENTAL DISORDERS

KW - FRAMEWORK

KW - NETWORK

KW - RISK

KW - SCHIZOPHRENIA

KW - EXPRESSION

KW - DISCOVERY

KW - 3111 Biomedicine

U2 - 10.1038/nature13772

DO - 10.1038/nature13772

M3 - Article

VL - 515

SP - 209-U119

JO - Nature

JF - Nature

SN - 0028-0836

IS - 7526

ER -