Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes

T. A. Nissinen; J. Degerman; M. Räsänen; A. R. Poikonen; S. Koskinen; E. Mervaala; A. Pasternack; O. Ritvos; R. Kivela; J. J. Hulmi

doi:10.1038/srep32695

Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes

T. A. Nissinen, J. Degerman, M. Räsänen, A. R. Poikonen, S. Koskinen, E. Mervaala, A. Pasternack, O. Ritvos, R. Kivela, J. J. Hulmi

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	32695
Tidskrift	Scientific Reports
Volym	6
Antal sidor	16
ISSN	2045-2322
DOI	https://doi.org/10.1038/srep32695
Status	Publicerad - 26 sep. 2016
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper

Åtkomst av dokument

10.1038/srep32695

srep32695Slutlig publicerad version, 1,76 MB

Citera det här

Nissinen, T. A., Degerman, J., Räsänen, M., Poikonen, A. R., Koskinen, S., Mervaala, E., Pasternack, A., Ritvos, O., Kivela, R., & Hulmi, J. J. (2016). Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Scientific Reports, 6, [32695]. https://doi.org/10.1038/srep32695

@article{0b3efe1920414088a012fd06235118fc,

title = "Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes",

keywords = "ACUTE DOXORUBICIN CARDIOTOXICITY, SKELETAL-MUSCLE, EXERCISE PROTECTS, CANCER CACHEXIA, MDX MICE, EXPRESSION, MYOSTATIN, RECEPTOR, HEART, CARDIOMYOPATHY, 3111 Biomedicine",

author = "Nissinen, {T. A.} and J. Degerman and M. R{\"a}s{\"a}nen and Poikonen, {A. R.} and S. Koskinen and E. Mervaala and A. Pasternack and O. Ritvos and R. Kivela and Hulmi, {J. J.}",

year = "2016",

month = sep,

day = "26",

doi = "10.1038/srep32695",

language = "English",

volume = "6",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

}

Nissinen, TA, Degerman, J, Räsänen, M, Poikonen, AR, Koskinen, S, Mervaala, E , Pasternack, A , Ritvos, O , Kivela, R & Hulmi, JJ 2016, 'Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes', Scientific Reports, vol. 6, 32695. https://doi.org/10.1038/srep32695

Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. / Nissinen, T. A.; Degerman, J.; Räsänen, M.; Poikonen, A. R.; Koskinen, S.; Mervaala, E.; Pasternack, A.; Ritvos, O.; Kivela, R.; Hulmi, J. J.

I: Scientific Reports, Vol. 6, 32695, 26.09.2016.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes

AU - Nissinen, T. A.

AU - Degerman, J.

AU - Räsänen, M.

AU - Poikonen, A. R.

AU - Koskinen, S.

AU - Mervaala, E.

AU - Pasternack, A.

AU - Ritvos, O.

AU - Kivela, R.

AU - Hulmi, J. J.

PY - 2016/9/26

Y1 - 2016/9/26

KW - ACUTE DOXORUBICIN CARDIOTOXICITY

KW - SKELETAL-MUSCLE

KW - EXERCISE PROTECTS

KW - CANCER CACHEXIA

KW - MDX MICE

KW - EXPRESSION

KW - MYOSTATIN

KW - RECEPTOR

KW - HEART

KW - CARDIOMYOPATHY

KW - 3111 Biomedicine

U2 - 10.1038/srep32695

DO - 10.1038/srep32695

M3 - Article

VL - 6

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 32695

ER -