Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1 alpha PARylation in db/db mice

Hong Wang; Sara Kuusela; Rita Rinnankoski-Tuikka; Vincent Dumont; Rim Bouslama; Usama Abo Ramadan; Jo Waaler; Anni-Maija Linden; Nai-Wen Chi; Stefan Krauss; Eija Pirinen; Sanna Lehtonen

doi:10.1038/s41366-020-0573-z

Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1 alpha PARylation in db/db mice

Hong Wang
, Sara Kuusela
, Rita Rinnankoski-Tuikka
, Vincent Dumont
, Rim Bouslama
, Usama Abo Ramadan
, Jo Waaler
, Anni-Maija Linden
, Nai-Wen Chi
, Stefan Krauss
, Eija Pirinen
, Sanna Lehtonen

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	International Journal of Obesity
Volym	44
Nummer	8
Sidor (från-till)	1691-1702
Antal sidor	12
ISSN	0307-0565
DOI	https://doi.org/10.1038/s41366-020-0573-z
Status	Publicerad - aug. 2020
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3121 Allmänmedicin, inre medicin och annan klinisk medicin
3143 Nutrition

Åtkomst av dokument

10.1038/s41366-020-0573-z

s41366-020-0573-zSlutlig publicerad version, 2,05 MBLicens: CC BY

Citera det här

Wang, H., Kuusela, S., Rinnankoski-Tuikka, R., Dumont, V., Bouslama, R., Ramadan, U. A., Waaler, J., Linden, A.-M., Chi, N.-W., Krauss, S., Pirinen, E., & Lehtonen, S. (2020). Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1 alpha PARylation in db/db mice. International Journal of Obesity, 44(8), 1691-1702. https://doi.org/10.1038/s41366-020-0573-z

@article{905455622d394e029a73ee68446dcd1f,

title = "Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1 alpha PARylation in db/db mice",

keywords = "FATTY-ACID OXIDATION, RECEPTOR COACTIVATOR PGC-1-ALPHA, BETA-CELL FUNCTION, SKELETAL-MUSCLE, GLUCOSE-METABOLISM, ADIPOSE-TISSUE, PHARMACOLOGICAL INHIBITION, HEPATIC GLUCONEOGENESIS, MITOCHONDRIAL-FUNCTION, PGC-1 COACTIVATORS, 3121 General medicine, internal medicine and other clinical medicine, 3143 Nutrition",

author = "Hong Wang and Sara Kuusela and Rita Rinnankoski-Tuikka and Vincent Dumont and Rim Bouslama and Ramadan, \{Usama Abo\} and Jo Waaler and Anni-Maija Linden and Nai-Wen Chi and Stefan Krauss and Eija Pirinen and Sanna Lehtonen",

year = "2020",

month = aug,

doi = "10.1038/s41366-020-0573-z",

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volume = "44",

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journal = "International Journal of Obesity",

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TY - JOUR

T1 - Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1 alpha PARylation in db/db mice

AU - Wang, Hong

AU - Kuusela, Sara

AU - Rinnankoski-Tuikka, Rita

AU - Dumont, Vincent

AU - Bouslama, Rim

AU - Ramadan, Usama Abo

AU - Waaler, Jo

AU - Linden, Anni-Maija

AU - Chi, Nai-Wen

AU - Krauss, Stefan

AU - Pirinen, Eija

AU - Lehtonen, Sanna

PY - 2020/8

Y1 - 2020/8

KW - FATTY-ACID OXIDATION

KW - RECEPTOR COACTIVATOR PGC-1-ALPHA

KW - BETA-CELL FUNCTION

KW - SKELETAL-MUSCLE

KW - GLUCOSE-METABOLISM

KW - ADIPOSE-TISSUE

KW - PHARMACOLOGICAL INHIBITION

KW - HEPATIC GLUCONEOGENESIS

KW - MITOCHONDRIAL-FUNCTION

KW - PGC-1 COACTIVATORS

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3143 Nutrition

U2 - 10.1038/s41366-020-0573-z

DO - 10.1038/s41366-020-0573-z

M3 - Article

SN - 0307-0565

VL - 44

SP - 1691

EP - 1702

JO - International Journal of Obesity

JF - International Journal of Obesity

IS - 8

ER -