Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Jing Tang; Leena Karhinen; Tao Xu; Agnieszka Szwajda; Bhagwan Yadav; Krister Wennerberg; Tero Aittokallio

doi:10.1371/journal.pcbi.1003226

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Jing Tang, Leena Karhinen, Tao Xu, Agnieszka Szwajda, Bhagwan Yadav, Krister Wennerberg, Tero Aittokallio

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	PLoS Computational Biology
Volym	9
Utgåva	9
Sidor (från-till)	Article Number: e1003226
Antal sidor	16
ISSN	1553-7358
DOI	https://doi.org/10.1371/journal.pcbi.1003226
Status	Publicerad - sep 2013
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper

Åtkomst av dokument

10.1371/journal.pcbi.1003226

FIMM High Throughput Biomedicine Unit
Päivi Tammela (Chef)
Institutet för molekylärmedicin i Finland
Utrustning/facilitet: Central servicefacilitet

Citera det här

@article{63303216533240cd874ebfffbc9f5c08,

title = "Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways",

keywords = "DRUG-COMBINATIONS, GENETIC INTERACTIONS, QUANTITATIVE-ANALYSIS, SYNTHETIC LETHALITY, METABOLIC NETWORKS, PANCREATIC-CANCER, CELLS, RNAI, IDENTIFICATION, SENSITIVITY, 3111 Biomedicine",

author = "Jing Tang and Leena Karhinen and Tao Xu and Agnieszka Szwajda and Bhagwan Yadav and Krister Wennerberg and Tero Aittokallio",

year = "2013",

month = sep,

doi = "10.1371/journal.pcbi.1003226",

language = "English",

volume = "9",

pages = " Article Number: e1003226",

journal = "PLoS Computational Biology",

issn = "1553-734X",

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}

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways. / Tang, Jing ; Karhinen, Leena; Xu, Tao; Szwajda, Agnieszka; Yadav, Bhagwan ; Wennerberg, Krister ; Aittokallio, Tero.

I: PLoS Computational Biology, Vol. 9, Nr. 9, 09.2013, s. Article Number: e1003226.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

TY - JOUR

T1 - Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

AU - Tang, Jing

AU - Karhinen, Leena

AU - Xu, Tao

AU - Szwajda, Agnieszka

AU - Yadav, Bhagwan

AU - Wennerberg, Krister

AU - Aittokallio, Tero

PY - 2013/9

Y1 - 2013/9

KW - DRUG-COMBINATIONS

KW - GENETIC INTERACTIONS

KW - QUANTITATIVE-ANALYSIS

KW - SYNTHETIC LETHALITY

KW - METABOLIC NETWORKS

KW - PANCREATIC-CANCER

KW - CELLS

KW - RNAI

KW - IDENTIFICATION

KW - SENSITIVITY

KW - 3111 Biomedicine

U2 - 10.1371/journal.pcbi.1003226

DO - 10.1371/journal.pcbi.1003226

M3 - Article

VL - 9

SP - Article Number: e1003226

JO - PLoS Computational Biology

JF - PLoS Computational Biology

SN - 1553-734X

IS - 9

ER -

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

Vetenskapsgrenar

Åtkomst av dokument

FIMM High Throughput Biomedicine Unit

Citera det här