The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers

Kristian Semjonov, Karin Kogermann, Ivo Laidmae, Osmo Antikainen, Clare J. Strachan, Henrik Ehlers, Jouko Yliruusi, Jyrki Heinämäki

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Originalspråkengelska
TidskriftEuropean Journal of Pharmaceutical Sciences
Volym97
Sidor (från-till)237-246
Antal sidor10
ISSN0928-0987
DOI
StatusPublicerad - 15 jan 2017
MoE-publikationstypA1 Tidskriftsartikel-refererad

Vetenskapsgrenar

  • 317 Farmaci

Citera det här

@article{d3d786de500a4ed498bc35d00fe76270,
title = "The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers",
keywords = "Solid dispersion, Two-phase systems, Supercooled molten mixture, Indomethacin, Soluplus (R), Xylitol, Solid-state stability, WATER-SOLUBLE DRUGS, AMORPHOUS INDOMETHACIN, THERMAL-ANALYSIS, CRYSTALLIZATION, DISSOLUTION, SOLUBILITY, STATE, POLY(VINYLPYRROLIDONE), AMORPHIZATION, MISCIBILITY, 317 Pharmacy",
author = "Kristian Semjonov and Karin Kogermann and Ivo Laidmae and Osmo Antikainen and Strachan, {Clare J.} and Henrik Ehlers and Jouko Yliruusi and Jyrki Hein{\"a}m{\"a}ki",
year = "2017",
month = "1",
day = "15",
doi = "10.1016/j.ejps.2016.11.019",
language = "English",
volume = "97",
pages = "237--246",
journal = "European Journal of Pharmaceutical Sciences",
issn = "0928-0987",
publisher = "Elsevier Scientific Publ. Co",

}

TY - JOUR

T1 - The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers

AU - Semjonov, Kristian

AU - Kogermann, Karin

AU - Laidmae, Ivo

AU - Antikainen, Osmo

AU - Strachan, Clare J.

AU - Ehlers, Henrik

AU - Yliruusi, Jouko

AU - Heinämäki, Jyrki

PY - 2017/1/15

Y1 - 2017/1/15

KW - Solid dispersion

KW - Two-phase systems

KW - Supercooled molten mixture

KW - Indomethacin

KW - Soluplus (R)

KW - Xylitol

KW - Solid-state stability

KW - WATER-SOLUBLE DRUGS

KW - AMORPHOUS INDOMETHACIN

KW - THERMAL-ANALYSIS

KW - CRYSTALLIZATION

KW - DISSOLUTION

KW - SOLUBILITY

KW - STATE

KW - POLY(VINYLPYRROLIDONE)

KW - AMORPHIZATION

KW - MISCIBILITY

KW - 317 Pharmacy

U2 - 10.1016/j.ejps.2016.11.019

DO - 10.1016/j.ejps.2016.11.019

M3 - Article

VL - 97

SP - 237

EP - 246

JO - European Journal of Pharmaceutical Sciences

JF - European Journal of Pharmaceutical Sciences

SN - 0928-0987

ER -