The phylodynamics of SARS-CoV-2 during 2020 in Finland

Phuoc Truong Nguyen; Ravi Kant; Frederik Van den Broeck; Maija T. Suvanto; Hussein Alburkat; Jenni Virtanen; Ella Ahvenainen; Robert Castren; Samuel L. Hong; Guy Baele; Maarit J. Ahava; Hanna Jarva; Suvi Tuulia Jokiranta; Hannimari Kallio-Kokko; Eliisa Kekäläinen; Vesa Kirjavainen; Elisa Kortela; Satu Kurkela; Maija Lappalainen; Hanna Liimatainen; Marc A. Suchard; Sari Hannula; Pekka Ellonen; Tarja Sironen; Philippe Lemey; Olli Vapalahti; Teemu Smura

doi:10.1038/s43856-022-00130-7

The phylodynamics of SARS-CoV-2 during 2020 in Finland

Phuoc Truong Nguyen, Ravi Kant, Frederik Van den Broeck, Maija T. Suvanto, Hussein Alburkat, Jenni Virtanen, Ella Ahvenainen, Robert Castren, Samuel L. Hong, Guy Baele, Maarit J. Ahava, Hanna Jarva, Suvi Tuulia Jokiranta, Hannimari Kallio-Kokko, Eliisa Kekäläinen, Vesa Kirjavainen, Elisa Kortela, Satu Kurkela, Maija Lappalainen, Hanna LiimatainenMarc A. Suchard, Sari Hannula, Pekka Ellonen, Tarja Sironen, Philippe Lemey, Olli Vapalahti, Teemu Smura

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Sammanfattning

Finland has had a low incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections as compared to most European countries. Here we report the origins and turnover of SARS-CoV-2 lineages circulating in Finland in 2020. SARS-CoV-2 introduced to Finland in January 2020 and spread rapidly across southern Finland during spring. We observed rapid turnover among Finnish lineages during this period. Clade 20C became the most prevalent among sequenced cases and was replaced by other strains in fall 2020. Bayesian phylogeographic reconstructions suggested 42 independent introductions into Finland during spring 2020, mainly from Italy, Austria, and Spain, which might have been the source for a third of cases. The investigations of the original introductions of SARS-CoV-2 to Finland during the early stages of the pandemic and of the subsequent lineage dynamics could be utilized to assess the role of transboundary movements and effects of early intervention and public health measures.

Originalspråk	engelska
Artikelnummer	65
Tidskrift	Communication Medicine
Volym	2
Antal sidor	9
ISSN	2730-664X
DOI	https://doi.org/10.1038/s43856-022-00130-7
Status	Publicerad - 10 juni 2022
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3121 Allmänmedicin, inre medicin och annan klinisk medicin

Åtkomst av dokument

10.1038/s43856-022-00130-7Licens: CC BY

s43856-022-00130-7Slutlig publicerad version, 2 MBLicens: CC BY

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Nguyen, P. T., Kant, R., Broeck, F. V. D., Suvanto, M. T., Alburkat, H., Virtanen, J., Ahvenainen, E., Castren, R., Hong, S. L., Baele, G., Ahava, M. J., Jarva, H., Jokiranta, S. T., Kallio-Kokko, H., Kekäläinen, E., Kirjavainen, V., Kortela, E., Kurkela, S., Lappalainen, M., ... Smura, T. (2022). The phylodynamics of SARS-CoV-2 during 2020 in Finland. Communication Medicine, 2, [65]. https://doi.org/10.1038/s43856-022-00130-7

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title = "The phylodynamics of SARS-CoV-2 during 2020 in Finland",

abstract = "Finland has had a low incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections as compared to most European countries. Here we report the origins and turnover of SARS-CoV-2 lineages circulating in Finland in 2020. SARS-CoV-2 introduced to Finland in January 2020 and spread rapidly across southern Finland during spring. We observed rapid turnover among Finnish lineages during this period. Clade 20C became the most prevalent among sequenced cases and was replaced by other strains in fall 2020. Bayesian phylogeographic reconstructions suggested 42 independent introductions into Finland during spring 2020, mainly from Italy, Austria, and Spain, which might have been the source for a third of cases. The investigations of the original introductions of SARS-CoV-2 to Finland during the early stages of the pandemic and of the subsequent lineage dynamics could be utilized to assess the role of transboundary movements and effects of early intervention and public health measures.",

keywords = "3121 General medicine, internal medicine and other clinical medicine",

author = "Nguyen, {Phuoc Truong} and Ravi Kant and Broeck, {Frederik Van den} and Suvanto, {Maija T.} and Hussein Alburkat and Jenni Virtanen and Ella Ahvenainen and Robert Castren and Hong, {Samuel L.} and Guy Baele and Ahava, {Maarit J.} and Hanna Jarva and Jokiranta, {Suvi Tuulia} and Hannimari Kallio-Kokko and Eliisa Kek{\"a}l{\"a}inen and Vesa Kirjavainen and Elisa Kortela and Satu Kurkela and Maija Lappalainen and Hanna Liimatainen and Suchard, {Marc A.} and Sari Hannula and Pekka Ellonen and Tarja Sironen and Philippe Lemey and Olli Vapalahti and Teemu Smura",

year = "2022",

month = jun,

day = "10",

doi = "10.1038/s43856-022-00130-7",

language = "English",

volume = "2",

journal = "Communication Medicine",

issn = "2730-664X",

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Nguyen, PT, Kant, R, Broeck, FVD, Suvanto, MT , Alburkat, H , Virtanen, J, Ahvenainen, E, Castren, R, Hong, SL, Baele, G, Ahava, MJ , Jarva, H, Jokiranta, ST, Kallio-Kokko, H , Kekäläinen, E , Kirjavainen, V, Kortela, E, Kurkela, S , Lappalainen, M , Liimatainen, H, Suchard, MA, Hannula, S, Ellonen, P, Sironen, T, Lemey, P, Vapalahti, O & Smura, T 2022, 'The phylodynamics of SARS-CoV-2 during 2020 in Finland', Communication Medicine, vol. 2, 65. https://doi.org/10.1038/s43856-022-00130-7

TY - JOUR

T1 - The phylodynamics of SARS-CoV-2 during 2020 in Finland

AU - Nguyen, Phuoc Truong

AU - Kant, Ravi

AU - Broeck, Frederik Van den

AU - Suvanto, Maija T.

AU - Alburkat, Hussein

AU - Virtanen, Jenni

AU - Ahvenainen, Ella

AU - Castren, Robert

AU - Hong, Samuel L.

AU - Baele, Guy

AU - Ahava, Maarit J.

AU - Jarva, Hanna

AU - Jokiranta, Suvi Tuulia

AU - Kallio-Kokko, Hannimari

AU - Kekäläinen, Eliisa

AU - Kirjavainen, Vesa

AU - Kortela, Elisa

AU - Kurkela, Satu

AU - Lappalainen, Maija

AU - Liimatainen, Hanna

AU - Suchard, Marc A.

AU - Hannula, Sari

AU - Ellonen, Pekka

AU - Sironen, Tarja

AU - Lemey, Philippe

AU - Vapalahti, Olli

AU - Smura, Teemu

PY - 2022/6/10

Y1 - 2022/6/10

N2 - Finland has had a low incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections as compared to most European countries. Here we report the origins and turnover of SARS-CoV-2 lineages circulating in Finland in 2020. SARS-CoV-2 introduced to Finland in January 2020 and spread rapidly across southern Finland during spring. We observed rapid turnover among Finnish lineages during this period. Clade 20C became the most prevalent among sequenced cases and was replaced by other strains in fall 2020. Bayesian phylogeographic reconstructions suggested 42 independent introductions into Finland during spring 2020, mainly from Italy, Austria, and Spain, which might have been the source for a third of cases. The investigations of the original introductions of SARS-CoV-2 to Finland during the early stages of the pandemic and of the subsequent lineage dynamics could be utilized to assess the role of transboundary movements and effects of early intervention and public health measures.

AB - Finland has had a low incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections as compared to most European countries. Here we report the origins and turnover of SARS-CoV-2 lineages circulating in Finland in 2020. SARS-CoV-2 introduced to Finland in January 2020 and spread rapidly across southern Finland during spring. We observed rapid turnover among Finnish lineages during this period. Clade 20C became the most prevalent among sequenced cases and was replaced by other strains in fall 2020. Bayesian phylogeographic reconstructions suggested 42 independent introductions into Finland during spring 2020, mainly from Italy, Austria, and Spain, which might have been the source for a third of cases. The investigations of the original introductions of SARS-CoV-2 to Finland during the early stages of the pandemic and of the subsequent lineage dynamics could be utilized to assess the role of transboundary movements and effects of early intervention and public health measures.

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1038/s43856-022-00130-7

DO - 10.1038/s43856-022-00130-7

M3 - Article

VL - 2

JO - Communication Medicine

JF - Communication Medicine

SN - 2730-664X

M1 - 65

ER -