The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha

Vikash Chandra; Hazem Ibrahim; Clementine Halliez; Rashmi B. Prasad; Federica Vecchio; Om Prakash Dwivedi; Jouni Kvist; Diego Balboa; Jonna Saarimäki-Vire; Hossam Montaser; Tom Barsby; Väinö Lithovius; Isabella Artner; Swetha Gopalakrishnan; Leif Groop; Roberto Mallone; Decio L. Eizirik; Timo Otonkoski

doi:10.1038/s41467-022-34069-z

The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha

Vikash Chandra, Hazem Ibrahim, Clementine Halliez, Rashmi B. Prasad, Federica Vecchio, Om Prakash Dwivedi, Jouni Kvist, Diego Balboa, Jonna Saarimäki-Vire, Hossam Montaser, Tom Barsby, Väinö Lithovius, Isabella Artner, Swetha Gopalakrishnan, Leif Groop, Roberto Mallone, Decio L. Eizirik, Timo Otonkoski

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Artikelnummer	6363
Tidskrift	Nature Communications
Volym	13
Nummer	1
Antal sidor	16
ISSN	2041-1723
DOI	https://doi.org/10.1038/s41467-022-34069-z
Status	Publicerad - 26 okt. 2022
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3111 Biomedicinska vetenskaper
1184 Genetik, utvecklingsbiologi, fysiologi

Åtkomst av dokument

10.1038/s41467-022-34069-zLicens: CC BY

s41467-022-34069-zSlutlig publicerad version, 5,65 MBLicens: CC BY

Citera det här

Chandra, V., Ibrahim, H., Halliez, C., Prasad, R. B., Vecchio, F., Dwivedi, O. P., Kvist, J., Balboa, D., Saarimäki-Vire, J., Montaser, H., Barsby, T., Lithovius, V., Artner, I., Gopalakrishnan, S., Groop, L., Mallone, R., Eizirik, D. L., & Otonkoski, T. (2022). The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha. Nature Communications, 13(1), Artikel 6363. https://doi.org/10.1038/s41467-022-34069-z

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title = "The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha",

keywords = "ENDOCRINE DIFFERENTIATION, R-PACKAGE, EXPRESSION, APOPTOSIS, 3111 Biomedicine, 1184 Genetics, developmental biology, physiology",

author = "Vikash Chandra and Hazem Ibrahim and Clementine Halliez and Prasad, {Rashmi B.} and Federica Vecchio and Dwivedi, {Om Prakash} and Jouni Kvist and Diego Balboa and Jonna Saarim{\"a}ki-Vire and Hossam Montaser and Tom Barsby and V{\"a}in{\"o} Lithovius and Isabella Artner and Swetha Gopalakrishnan and Leif Groop and Roberto Mallone and Eizirik, {Decio L.} and Timo Otonkoski",

year = "2022",

month = oct,

day = "26",

doi = "10.1038/s41467-022-34069-z",

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Chandra, V , Ibrahim, H, Halliez, C, Prasad, RB, Vecchio, F, Dwivedi, OP , Kvist, J , Balboa, D , Saarimäki-Vire, J , Montaser, H, Barsby, T, Lithovius, V, Artner, I, Gopalakrishnan, S , Groop, L, Mallone, R, Eizirik, DL & Otonkoski, T 2022, 'The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha', Nature Communications, vol. 13, nr. 1, 6363. https://doi.org/10.1038/s41467-022-34069-z

TY - JOUR

T1 - The type 1 diabetes gene TYK2 regulates beta-cell development and its responses to interferon-alpha

AU - Chandra, Vikash

AU - Ibrahim, Hazem

AU - Halliez, Clementine

AU - Prasad, Rashmi B.

AU - Vecchio, Federica

AU - Dwivedi, Om Prakash

AU - Kvist, Jouni

AU - Balboa, Diego

AU - Saarimäki-Vire, Jonna

AU - Montaser, Hossam

AU - Barsby, Tom

AU - Lithovius, Väinö

AU - Artner, Isabella

AU - Gopalakrishnan, Swetha

AU - Groop, Leif

AU - Mallone, Roberto

AU - Eizirik, Decio L.

AU - Otonkoski, Timo

PY - 2022/10/26

Y1 - 2022/10/26

KW - ENDOCRINE DIFFERENTIATION

KW - R-PACKAGE

KW - EXPRESSION

KW - APOPTOSIS

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/s41467-022-34069-z

DO - 10.1038/s41467-022-34069-z

M3 - Article

SN - 2041-1723

VL - 13

JO - Nature Communications

JF - Nature Communications

IS - 1

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