Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity

Minttu Kansikas; Laura Vähätalo; Jukka Kantelinen; Mariann Kasela; Jaana Putula; Anni Døhlen; Pauliina Paloviita; Emmi Kärkkäinen; Niklas Lahti; Philippe Arnez; Sami Kilpinen; Beatriz Alcala-Repo; Kirsi Pylvänäinen; Minna Pöyhönen; Päivi Peltomäki; Heikki J. Järvinen; Toni T. Seppälä; Laura Renkonen-Sinisalo; Anna Lepistö; Jukka-Pekka Mecklin; Minna Nyström

doi:10.1158/2767-9764.CRC-22-0384

Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity

Minttu Kansikas, Laura Vähätalo, Jukka Kantelinen, Mariann Kasela, Jaana Putula, Anni Døhlen, Pauliina Paloviita, Emmi Kärkkäinen, Niklas Lahti, Philippe Arnez, Sami Kilpinen, Beatriz Alcala-Repo, Kirsi Pylvänäinen, Minna Pöyhönen, Päivi Peltomäki, Heikki J. Järvinen, Toni T. Seppälä, Laura Renkonen-Sinisalo, Anna Lepistö, Jukka-Pekka MecklinMinna Nyström

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Originalspråk	engelska
Tidskrift	Cancer research communications
Volym	3
Nummer	3
Sidor (från-till)	361-370
Antal sidor	10
ISSN	2767-9764
DOI	https://doi.org/10.1158/2767-9764.CRC-22-0384
Status	Publicerad - mars 2023
MoE-publikationstyp	A1 Tidskriftsartikel-refererad

Vetenskapsgrenar

3122 Cancersjukdomar

Åtkomst av dokument

10.1158/2767-9764.CRC-22-0384Licens: CC BY

crc-22-0384Slutlig publicerad version, 806 KBLicens: CC BY

Citera det här

Kansikas, M., Vähätalo, L., Kantelinen, J., Kasela, M., Putula, J., Døhlen, A., Paloviita, P., Kärkkäinen, E., Lahti, N., Arnez, P., Kilpinen, S., Alcala-Repo, B., Pylvänäinen, K., Pöyhönen, M., Peltomäki, P., Järvinen, H. J., Seppälä, T. T., Renkonen-Sinisalo, L., Lepistö, A., ... Nyström, M. (2023). Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity. Cancer research communications, 3(3), 361-370. https://doi.org/10.1158/2767-9764.CRC-22-0384

@article{326673a024fd4e4a87ba4d71e759dc71,

title = "Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity",

keywords = "3122 Cancers, Nonpolyposis colorectal-cancer, Endometrial cancer, Functional-analysis, Hereditary cancer, Mutations, Variants, Criteria, Risk, Msh2, Recommendations",

author = "Minttu Kansikas and Laura V{\"a}h{\"a}talo and Jukka Kantelinen and Mariann Kasela and Jaana Putula and Anni D{\o}hlen and Pauliina Paloviita and Emmi K{\"a}rkk{\"a}inen and Niklas Lahti and Philippe Arnez and Sami Kilpinen and Beatriz Alcala-Repo and Kirsi Pylv{\"a}n{\"a}inen and Minna P{\"o}yh{\"o}nen and P{\"a}ivi Peltom{\"a}ki and J{\"a}rvinen, {Heikki J.} and Sepp{\"a}l{\"a}, {Toni T.} and Laura Renkonen-Sinisalo and Anna Lepist{\"o} and Jukka-Pekka Mecklin and Minna Nystr{\"o}m",

year = "2023",

month = mar,

doi = "10.1158/2767-9764.CRC-22-0384",

language = "English",

volume = "3",

pages = "361--370",

journal = " Cancer research communications",

issn = "2767-9764",

publisher = "American Association for Cancer Research",

number = "3",

}

Kansikas, M, Vähätalo, L, Kantelinen, J, Kasela, M, Putula, J, Døhlen, A, Paloviita, P, Kärkkäinen, E, Lahti, N, Arnez, P, Kilpinen, S, Alcala-Repo, B, Pylvänäinen, K, Pöyhönen, M , Peltomäki, P , Järvinen, HJ , Seppälä, TT, Renkonen-Sinisalo, L, Lepistö, A, Mecklin, J-P & Nyström, M 2023, 'Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity', Cancer research communications, vol. 3, nr. 3, s. 361-370. https://doi.org/10.1158/2767-9764.CRC-22-0384

TY - JOUR

T1 - Tumor-independent Detection of Inherited Mismatch Repair Deficiency for the Diagnosis of Lynch Syndrome with High Specificity and Sensitivity

AU - Kansikas, Minttu

AU - Vähätalo, Laura

AU - Kantelinen, Jukka

AU - Kasela, Mariann

AU - Putula, Jaana

AU - Døhlen, Anni

AU - Paloviita, Pauliina

AU - Kärkkäinen, Emmi

AU - Lahti, Niklas

AU - Arnez, Philippe

AU - Kilpinen, Sami

AU - Alcala-Repo, Beatriz

AU - Pylvänäinen, Kirsi

AU - Pöyhönen, Minna

AU - Peltomäki, Päivi

AU - Järvinen, Heikki J.

AU - Seppälä, Toni T.

AU - Renkonen-Sinisalo, Laura

AU - Lepistö, Anna

AU - Mecklin, Jukka-Pekka

AU - Nyström, Minna

PY - 2023/3

Y1 - 2023/3

KW - 3122 Cancers

KW - Nonpolyposis colorectal-cancer

KW - Endometrial cancer

KW - Functional-analysis

KW - Hereditary cancer

KW - Mutations

KW - Variants

KW - Criteria

KW - Risk

KW - Msh2

KW - Recommendations

U2 - 10.1158/2767-9764.CRC-22-0384

DO - 10.1158/2767-9764.CRC-22-0384

M3 - Article

SN - 2767-9764

VL - 3

SP - 361

EP - 370

JO - Cancer research communications

JF - Cancer research communications

IS - 3

ER -